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Mechanical ventilation (MV) is a life-saving intervention for patients with acute respiratory failure (ARF) in the ICU. However, inappropriate ventilator settings could cause ventilator-induced lung injury (VILI). Also, clinicians workload…

Machine Learning · Computer Science 2026-03-13 Hang Yu , Huidong Liu , Qingchen Zhang , William Joy , Kateryna Nikulina , Andreas A. Schuppert , Sina Saffaran , Declan Bates

Mechanical ventilation is a critical life support intervention that delivers controlled air and oxygen to a patient's lungs, assisting or replacing spontaneous breathing. While several data-driven approaches have been proposed to optimize…

Machine Learning · Computer Science 2025-01-10 Joo Seung Lee , Malini Mahendra , Anil Aswani

Invasive mechanical ventilation (MV) is a life-sustaining therapy commonly used in the intensive care unit (ICU) for patients with severe and acute conditions. These patients frequently rely on MV for breathing. Given the high risk of death…

Machine Learning · Computer Science 2026-01-16 Muhammad Hamza Yousuf , Jason Li , Sahar Vahdati , Raphael Theilen , Jakob Wittenstein , Jens Lehmann

Mechanical Ventilation (MV) is a critical life-support intervention in intensive care units (ICUs). However, optimal ventilator settings are challenging to determine because of the complexity of balancing patient-specific physiological…

Machine Learning · Computer Science 2024-12-18 Niloufar Eghbali , Tuka Alhanai , Mohammad M. Ghassemi

The management of invasive mechanical ventilation, and the regulation of sedation and analgesia during ventilation, constitutes a major part of the care of patients admitted to intensive care units. Both prolonged dependence on mechanical…

Artificial Intelligence · Computer Science 2017-04-24 Niranjani Prasad , Li-Fang Cheng , Corey Chivers , Michael Draugelis , Barbara E Engelhardt

Cost-effective asset management is an area of interest across several industries. Specifically, this paper develops a deep reinforcement learning (DRL) solution to automatically determine an optimal rehabilitation policy for continuously…

Machine Learning · Computer Science 2023-04-19 Zaharah A. Bukhsh , Nils Jansen , Hajo Molegraaf

Patients with severe Coronavirus disease 19 (COVID-19) typically require supplemental oxygen as an essential treatment. We developed a machine learning algorithm, based on a deep Reinforcement Learning (RL), for continuous management of…

Machine Learning · Computer Science 2021-11-09 Hua Zheng , Jiahao Zhu , Wei Xie , Judy Zhong

Reinforcement learning (RL) is a promising approach for optimizing HVAC control. RL offers a framework for improving system performance, reducing energy consumption, and enhancing cost efficiency. We benchmark two popular classical and deep…

Machine Learning · Computer Science 2023-08-11 Marshall Wang , John Willes , Thomas Jiralerspong , Matin Moezzi

Effective patient monitoring is vital for timely interventions and improved healthcare outcomes. Traditional monitoring systems often struggle to handle complex, dynamic environments with fluctuating vital signs, leading to delays in…

Machine Learning · Computer Science 2024-10-30 Thanveer Shaik , Xiaohui Tao , Lin Li , Haoran Xie , Hong-Ning Dai , Feng Zhao , Jianming Yong

Sepsis is a leading cause of mortality and its treatment is very expensive. Sepsis treatment is also very challenging because there is no consensus on what interventions work best and different patients respond very differently to the same…

Machine Learning · Computer Science 2022-03-29 Pramod Kaushik , Sneha Kummetha , Perusha Moodley , Raju S. Bapi

Reinforcement learning has been increasingly applied in monitoring applications because of its ability to learn from previous experiences and can make adaptive decisions. However, existing machine learning-based health monitoring…

Machine Learning · Computer Science 2024-10-28 Thanveer Shaik , Xiaohui Tao , Lin Li , Haoran Xie , U R Acharya , Raj Gururajan , Xujuan Zhou

This research study explores the applicability of Deep Reinforcement Learning (DRL) for thermal control based on Computational Fluid Dynamics. To accomplish that, the forced convection on a hot plate prone to a pulsating cooling jet with…

Numerical Analysis · Mathematics 2024-02-19 Sajad Salavatidezfouli , Giovanni Stabile , Gianluigi Rozza

Effectively leveraging large, previously collected datasets in reinforcement learning (RL) is a key challenge for large-scale real-world applications. Offline RL algorithms promise to learn effective policies from previously-collected,…

Machine Learning · Computer Science 2020-08-20 Aviral Kumar , Aurick Zhou , George Tucker , Sergey Levine

Replacing poorly performing existing controllers with smarter solutions will decrease the energy intensity of the building sector. Recently, controllers based on Deep Reinforcement Learning (DRL) have been shown to be more effective than…

Machine Learning · Computer Science 2022-03-11 Loris Di Natale , Bratislav Svetozarevic , Philipp Heer , Colin N. Jones

We develop a deep learning approach to predicting a set of ventilator parameters for a mechanically ventilated septic patient using a long and short term memory (LSTM) recurrent neural network (RNN) model. We focus on short-term predictions…

Quantitative Methods · Quantitative Biology 2022-02-23 Zhijun Zeng , Zhen Hou , Ting Li , Lei Deng , Jianguo Hou , Xinran Huang , Jun Li , Meirou Sun , Yunhan Wang , Qiyu Wu , Wenhao Zheng , Hua Jiang , Qi Wang

Attitude control of fixed-wing unmanned aerial vehicles (UAVs) is a difficult control problem in part due to uncertain nonlinear dynamics, actuator constraints, and coupled longitudinal and lateral motions. Current state-of-the-art…

Systems and Control · Electrical Eng. & Systems 2023-04-20 Eivind Bøhn , Erlend M. Coates , Dirk Reinhardt , Tor Arne Johansen

Mechanical ventilation is one of the most widely used therapies in the ICU. However, despite broad application from anaesthesia to COVID-related life support, many injurious challenges remain. We frame these as a control problem:…

Much attention has been devoted recently to the development of machine learning algorithms with the goal of improving treatment policies in healthcare. Reinforcement learning (RL) is a sub-field within machine learning that is concerned…

Clinical decision support systems (CDSS) will play an in-creasing role in improving the quality of medical care for critically ill patients. However, due to limitations in current informatics infrastructure, CDSS do not always have…

Machine Learning · Computer Science 2019-05-01 Gregory B. Rehm , Brooks T. Kuhn , Jimmy Nguyen , Nicholas R. Anderson , Chen-Nee Chuah , Jason Y. Adams

This study explores the application of deep reinforcement learning (RL) to design an airfoil pitch controller capable of minimizing lift variations in randomly disturbed flows. The controller, treated as an agent in a partially observable…

Fluid Dynamics · Physics 2024-04-03 Diederik Beckers , Jeff D. Eldredge
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