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High throughput technologies have become the practice of choice for comparative studies in biomedical applications. Limited number of sample points due to sequencing cost or access to organisms of interest necessitates the development of…

Methodology · Statistics 2018-07-17 Ariana Broumand , Siamak Zamani Dadaneh

Chronic diseases are long-lasting conditions that require lifelong medical attention. Using big EMR data, we have developed early disease risk prediction models for five common chronic diseases: diabetes, hypertension, CKD, COPD, and…

Machine Learning · Computer Science 2026-03-13 Shaheer Ahmad Khan , Muhammad Usamah Shahid , Muddassar Farooq

When testing for infections, the standard method is to test each subject individually. If testing methodology is such that samples from multiple subjects can be efficiently combined and tested at once, yielding a positive results if any one…

Methodology · Statistics 2020-04-01 Anže Slosar

Contrastive Representation Learning (CRL) has achieved strong empirical success in multiple machine learning disciplines, yet its theoretical sample complexity remains poorly understood. Existing analyses usually assume that input tuples…

Machine Learning · Statistics 2026-05-29 Nong Minh Hieu , Antoine Ledent

Misclassification of binary responses, if ignored, may severely bias the maximum likelihood estimators (MLE) of regression parameters. For such data, a binary regression model incorporating misclassification probabilities is extensively…

Statistics Theory · Mathematics 2020-09-28 Arindam Chatterjee , Tathagata Bandyopadhyay , Sumanta Adhya

Spurious correlations that lead models to correct predictions for the wrong reasons pose a critical challenge for robust real-world generalization. Existing research attributes this issue to group imbalance and addresses it by maximizing…

Machine Learning · Computer Science 2025-12-02 Miaoyun Zhao , Chenrong Li , Qiang Zhang

Over the last year, the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its variants have highlighted the importance of screening tools with high diagnostic accuracy for new illnesses such as COVID-19. To that regard, deep…

Image and Video Processing · Electrical Eng. & Systems 2022-04-26 Danilo Avola , Andrea Bacciu , Luigi Cinque , Alessio Fagioli , Marco Raoul Marini , Riccardo Taiello

In Bayesian classification, it is important to establish a probabilistic model for each class for likelihood estimation. Most of the previous methods modeled the probability distribution in the whole sample space. However, real-world…

Machine Learning · Computer Science 2018-12-14 Chengsheng Mao , Lijuan Lu , Bin Hu

In this paper, we introduce a threshold-based framework for multiclass classification that generalizes the standard argmax rule. This is done by replacing the probabilistic interpretation of softmax outputs with a geometric one on the…

Machine Learning · Computer Science 2025-12-02 Francesco Marchetti , Edoardo Legnaro , Sabrina Guastavino

Binary classification involves predicting the label of an instance based on whether the model score for the positive class exceeds a threshold chosen based on the application requirements (e.g., maximizing recall for a precision bound).…

Machine Learning · Computer Science 2023-11-21 Gundeep Arora , Srujana Merugu , Anoop Saladi , Rajeev Rastogi

When presented with a binary classification problem where the data exhibits severe class imbalance, most standard predictive methods may fail to accurately model the minority class. We present a model based on Generative Adversarial…

Machine Learning · Computer Science 2022-04-20 Jonathan Gradstein , Moshe Salhov , Yoav Tulpan , Ofir Lindenbaum , Amir Averbuch

Subject selection plays a critical role in experimental studies, especially ones with human subjects. Anecdotal evidence suggests that many such studies, done at or near university campus settings suffer from selection bias, i.e., the…

Machine Learning · Computer Science 2020-12-21 Tahereh Arabghalizi , Alexandros Labrinidis

A common approach to aggregate classification estimates in an ensemble of decision trees is to either use voting or to average the probabilities for each class. The latter takes uncertainty into account, but not the reliability of the…

Machine Learning · Computer Science 2022-08-17 Florian Busch , Moritz Kulessa , Eneldo Loza Mencía , Hendrik Blockeel

Within the machine learning community, the widely-used uniform convergence framework has been used to answer the question of how complex, over-parameterized models can generalize well to new data. This approach bounds the test error of the…

Machine Learning · Statistics 2021-03-05 Ryan Theisen , Jason M. Klusowski , Michael W. Mahoney

In a broad range of classification and decision making problems, one is given the advice or predictions of several classifiers, of unknown reliability, over multiple questions or queries. This scenario is different from the standard…

Machine Learning · Statistics 2014-02-07 Fabio Parisi , Francesco Strino , Boaz Nadler , Yuval Kluger

Classification is a fundamental task in supervised learning, while achieving valid misclassification rate control remains challenging due to possibly the limited predictive capability of the classifiers or the intrinsic complexity of the…

Methodology · Statistics 2025-09-16 Yinrui Sun , Yin Xia

Selective inference methods are developed for group lasso estimators for use with a wide class of distributions and loss functions. The method includes the use of exponential family distributions, as well as quasi-likelihood modeling for…

Methodology · Statistics 2024-03-28 Yiling Huang , Sarah Pirenne , Snigdha Panigrahi , Gerda Claeskens

Class distribution plays an important role in learning deep classifiers. When the proportion of each class in the test set differs from the training set, the performance of classification nets usually degrades. Such a label distribution…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Wenao Ma , Cheng Chen , Shuang Zheng , Jing Qin , Huimao Zhang , Qi Dou

We analyze the methodological approach and validity of interpretation of using national-level time-series regression analyses relating epidemic outcomes to policies that estimate many models involving permutations of analytic choices (i.e.,…

Other Quantitative Biology · Quantitative Biology 2024-09-12 Jeremy D. Goldhaber-Fiebert

Checklists are simple decision aids that are often used to promote safety and reliability in clinical applications. In this paper, we present a method to learn checklists for clinical decision support. We represent predictive checklists as…

Machine Learning · Computer Science 2022-01-19 Haoran Zhang , Quaid Morris , Berk Ustun , Marzyeh Ghassemi
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