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We propose an unsupervised deep learning method for atlas based registration to achieve segmentation and spatial alignment of the embryonic brain in a single framework. Our approach consists of two sequential networks with a specifically…

Image and Video Processing · Electrical Eng. & Systems 2020-05-14 Wietske A. P. Bastiaansen , Melek Rousian , Régine P. M. Steegers-Theunissen , Wiro J. Niessen , Anton Koning , Stefan Klein

Automatic analyses and comparisons of different stages of embryonic development largely depend on a highly accurate spatiotemporal alignment of the investigated data sets. In this contribution, we assess multiple approaches for automatic…

Image and Video Processing · Electrical Eng. & Systems 2020-07-30 Manuel Traub , Johannes Stegmaier

Mortality prediction in intensive care units is considered one of the critical steps for efficiently treating patients in serious condition. As a result, various prediction models have been developed to address this problem based on modern…

Machine Learning · Computer Science 2020-12-15 Huachuan Wang , Yuanfei Bi

Infertility is a major global health issue, and while in-vitro fertilization has improved treatment outcomes, embryo selection remains a critical bottleneck. Time-lapse imaging enables continuous, non-invasive monitoring of embryo…

Automatic fetal brain tissue segmentation can enhance the quantitative assessment of brain development at this critical stage. Deep learning methods represent the state of the art in medical image segmentation and have also achieved…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Davood Karimi , Caitlin K. Rollins , Clemente Velasco-Annis , Abdelhakim Ouaalam , Ali Gholipour

Diffusion MRI (dMRI) provides unique insights into fetal brain microstructure in utero. Longitudinal and cross-sectional fetal dMRI studies can reveal crucial neurodevelopmental changes but require precise spatial alignment across scans and…

Image and Video Processing · Electrical Eng. & Systems 2025-05-13 Bo Li , Qi Zeng , Simon K. Warfield , Davood Karimi

Dynamic assessment of patient status (e.g. by an automated, continuously updated assessment of outcome) in the Intensive Care Unit (ICU) is of paramount importance for early alerting, decision support and resource allocation. Extraction and…

Machine Learning · Computer Science 2019-09-20 Jacob Deasy , Ari Ercole , Pietro Liò

Fetal brain imaging is a cornerstone of prenatal screening and early diagnosis of congenital anomalies. Knowledge of fetal gestational age is the key to the accurate assessment of brain development. This study develops an attention-based…

Computer Vision and Pattern Recognition · Computer Science 2018-12-19 Liyue Shen , Katie Shpanskaya , Edward Lee , Emily McKenna , Maryam Maleki , Quin Lu , Safwan Halabi , John Pauly , Kristen Yeom

Macroscopic, phenomenological models have proven useful as concise framings of our understandings in fields from statistical physics to economics to biology. Constructing a phenomenological model for development would provide a framework…

Cell Behavior · Quantitative Biology 2021-03-24 Brian D Leahy , Catherine Racowsky , Daniel Needleman

Early identification of patients at risk for clinical deterioration in the intensive care unit (ICU) remains a critical challenge. Delayed recognition of impending adverse events, including mortality, vasopressor initiation, and mechanical…

Machine Learning · Computer Science 2026-03-17 Binesh Sadanandan

Hypoxic-Ischemic Encephalopathy (HIE) affects 1 to 5 out of every 1,000 newborns, with 30% to 50% of cases resulting in adverse neurocognitive outcomes. However, these outcomes can only be reliably assessed as early as age 2. Therefore,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-11 Rina Bao , Sheng He , Ellen Grant , Yangming Ou

The International Society of Ultrasound advocates Intrapartum Ultrasound (US) Imaging in Obstetrics and Gynecology (ISUOG) to monitor labour progression through changes in fetal head position. Two reliable ultrasound-derived parameters that…

International Classification of Diseases(ICD) is an authoritative health care classification system of different diseases and conditions for clinical and management purposes. Considering the complicated and dedicated process to assign…

Computation and Language · Computer Science 2022-01-13 Haoran Shi , Pengtao Xie , Zhiting Hu , Ming Zhang , Eric P. Xing

The timing of cell divisions in early embryos during the In-Vitro Fertilization (IVF) process is a key predictor of embryo viability. However, observing cell divisions in Time-Lapse Monitoring (TLM) is a time-consuming process and highly…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Tien-Phat Nguyen , Trong-Thang Pham , Tri Nguyen , Hieu Le , Dung Nguyen , Hau Lam , Phong Nguyen , Jennifer Fowler , Minh-Triet Tran , Ngan Le

To improve the performance of Intensive Care Units (ICUs), the field of bio-statistics has developed scores which try to predict the likelihood of negative outcomes. These help evaluate the effectiveness of treatments and clinical practice,…

Machine Learning · Computer Science 2019-08-23 William Caicedo-Torres , Jairo Gutierrez

Preterm infants (born between 28 and 37 weeks of gestation) face elevated risks of neurodevelopmental delays, making early identification crucial for timely intervention. While deep learning-based volumetric segmentation of brain MRI scans…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Lexin Ren , Jiamiao Lu , Weichuan Zhang , Benqing Wu , Tuo Wang , Yi Liao , Jiapan Guo , Changming Sun , Liang Guo

We present a novel method for identification of the boundary of embryonic cells (blastomeres) in Hoffman Modulation Contrast (HMC) microscopic images that are taken between day one to day three. Identification of boundaries of blastomeres…

Computer Vision and Pattern Recognition · Computer Science 2019-10-15 Shakiba Kheradmand , Parvaneh Saeedi , Jason Au , John Havelock

A large number of children experience preventable developmental delays each year, yet the deployment of machine learning in new countries has been stymied by a data bottleneck: reliable models require thousands of samples, while new…

Machine Learning · Computer Science 2026-01-30 Md Muhtasim Munif Fahim , Md Rezaul Karim

Machine learning and deep learning methods have become essential for computer-assisted prediction in medicine, with a growing number of applications also in the field of mammography. Typically these algorithms are trained for a specific…

Image and Video Processing · Electrical Eng. & Systems 2021-12-03 Maria Wimmer , Gert Sluiter , David Major , Dimitrios Lenis , Astrid Berg , Theresa Neubauer , Katja Bühler