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Wavefront-shaping is a promising approach for imaging fluorescent targets deep inside scattering tissue despite strong aberrations. It enables focusing an incoming illumination into a single spot inside tissue, as well as correcting the…

Optics · Physics 2024-01-23 Dror Aizik , Anat Levin

Microscopy and optical imaging are drastically limited by the inhomogeneities encountered by the light while propagating from the object of interest to the detection system. In this context, adaptive optics and wavefront manipulation are…

Optics · Physics 2017-01-23 Diego Di Battista

Optical distortions can significantly deteriorate the measurement accuracy in imaging systems. Such distortions can occur at fluctuating phase boundaries as well as multiple-phase flows and result from the accompanied refractive index…

Applied Physics · Physics 2018-02-21 M. Teich , J. Grottke , H. Radner , L. BÜttner , J. W. Czarske

Aberrations limit optical systems in many situations, for example when imaging in biological tissue. Machine learning offers novel ways to improve imaging under such conditions by learning inverse models of aberrations. Learning requires…

Optics · Physics 2021-04-30 Ivan Vishniakou , Johannes D. Seelig

Transformation optics offers an unconventional approach to the control of electromagnetic fields. A transformation optical structure is designed by first applying a form-invariant coordinate transform to Maxwell's equations, in which part…

In astronomy or biological imaging, refractive index inhomogeneities of e.g. atmosphere or tissues induce optical aberrations which degrade the desired information hidden behind the medium. A standard approach consists in measuring these…

Optics · Physics 2023-06-01 Tengfei Wu , Marc Guillon , Gilles Tessier , Pascal Berto

Brillouin spectroscopy is a powerful optical technique for viscoelastic characterization of samples without contact. However, like all optical systems, Brillouin spectroscopy performances are degraded by optical aberrations, and have…

Optics · Physics 2018-02-09 Eitan Edrei , Giuliano Scarcelli

Diffraction-limited imaging through complex scattering media is a long sought after goal with important applications in biomedical research. In recent years, high resolution wavefront-shaping has emerged as a powerful approach to generate a…

Optics · Physics 2014-10-17 Ori Katz , Eran Small , Yefeng Guan , Yaron Silberberg

Adaptive optics (AO) has revolutionized imaging in {fields} from astronomy to microscopy by correcting optical aberrations. In label-free microscopes, however, conventional AO faces limitations due to the absence of guidestar and the need…

Commonly used wavefront sensors, the Shack Hartmann wavefront sensor and the pyramid wavefront sensor, for example, have large dynamic range or high sensitivity, trading one regime for the other. A new type of wavefront sensor is being…

Instrumentation and Methods for Astrophysics · Physics 2022-08-19 Meghan Farris O'Brien , Sebastiaan Y. Haffert , Joseph D. Long , Lauren Schatz , Jared R. Males , Kyle Van Gorkom , Alex Rodack

Control of light through a microscope objective with a high numerical aperture is a common requirement in applications such as optogenetics, adaptive optics, or laser processing. Light propagation, including polarization effects, can be…

Optics · Physics 2023-03-22 Ivan Vishniakou , Johannes D. Seelig

Imaging with optical resolution through highly scattering media is a long sought-after goal with important applications in deep tissue imaging. Although being the focus of numerous works, this goal was considered impractical until recently.…

Optics · Physics 2012-02-10 Ori Katz , Eran Small , Yaron Silberberg

End-to-end optimization, which simultaneously optimizes optics and algorithms, has emerged as a powerful data-driven method for computational imaging system design. This method achieves joint optimization through backpropagation by…

Computer Vision and Pattern Recognition · Computer Science 2025-08-08 Chi-Jui Ho , Yash Belhe , Steve Rotenberg , Ravi Ramamoorthi , Tzu-Mao Li , Nicholas Antipa

Optofluidic sensors based on highly dispersive two-dimensional photonic crystal waveguides are theoretically studied. Results show that these structures are strongly sensitive to the refractive index of the infiltrated liquid (nl), which is…

Optics · Physics 2011-11-10 Sanshui Xiao , Niels Asger Mortensen

Optical focusing through/inside scattering media, like multimode fiber and biological tissues, has significant impact in biomedicine yet considered challenging due to strong scattering nature of light. Previously, promising progress has…

Adaptive optics (AO) are reconfigurable devices that compensate for wavefront distortions or aberrations in optical systems such as microscopes, telescopes and ophthalmoscopes. Aberrations have detrimental effects that can reduce imaging…

Optics · Physics 2025-06-10 Biwei Zhang , Martin J. Booth , Qi Hu

Diffraction limited resolution adaptive optics (AO) correction in visible wavelengths requires a high performance control. In this paper we investigate infinite impulse response filters that optimize the wavefront correction: we tested…

Instrumentation and Methods for Astrophysics · Physics 2015-06-05 G. Agapito , C. Arcidiacono , F. Quirós-Pacheco , A. Puglisi , S. Esposito

The ability to form images through hair-thin optical fibres promises to open up new applications from biomedical imaging to industrial inspection. Unfortunately, deployment has been limited because small changes in mechanical deformation…

Over the past fifty years, wavefront sensing technology has continuously evolved from basic techniques to high-precision systems, serving as a core methodology in adaptive optics (AO). Beyond traditional wavefront retrieval methods based on…

Optics · Physics 2025-05-13 Rundong Fan , Zichao Wang , Pei Li , Lei Huang

Adaptive optics enables the deployment of interferometer-based spectroscopy without the need for moving parts necessary for scanning the interferometer arms. Here, we employ a Michelson Interferometer in conjunction with a Spatial Light…

Optics · Physics 2025-12-05 Jesneil Lauren Lewis , Ayan Banerjee