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The human brain extracts complex information from visual inputs, including objects, their spatial and semantic interrelations, and their interactions with the environment. However, a quantitative approach for studying this information…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Adrien Doerig , Tim C Kietzmann , Emily Allen , Yihan Wu , Thomas Naselaris , Kendrick Kay , Ian Charest

Functional magnetic resonance imaging (fMRI) is a neuroimaging modality that captures the blood oxygen level in a subject's brain while the subject either rests or performs a variety of functional tasks under different conditions. Given…

Computer Vision and Pattern Recognition · Computer Science 2021-01-20 Sam Nguyen , Brenda Ng , Alan D. Kaplan , Priyadip Ray

Advances in neuroscience and artificial intelligence have enabled preliminary decoding of brain activity. However, despite the progress, the interpretability of neural representations remains limited. A significant challenge arises from the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Hasib Aslam , Muhammad Talal Faiz , Muhammad Imran Malik

Recent progress in brain-guided image generation has improved the quality of fMRI-based reconstructions; however, fundamental challenges remain in preserving object-level structure and semantic fidelity. Many existing approaches overlook…

Image and Video Processing · Electrical Eng. & Systems 2026-04-14 Mohammad Moradi , Morteza Moradi , Marco Grassia , Giuseppe Mangioni

A standard approach in functional neuroimaging explores how a particular cognitive task activates a set of brain regions (one task-to-many regions mapping). Importantly though, the same neural system can be activated by inherently different…

Neurons and Cognition · Quantitative Biology 2016-03-23 Romy Lorenz , Ricardo Pio Monti , Ines R. Violante , Christoforos Anagnostopoulos , Aldo A. Faisal , Giovanni Montana , Robert Leech

Magnetic Resonance Imaging (MRI) plays a vital role in diagnosis, management and monitoring of many diseases. However, it is an inherently slow imaging technique. Over the last 20 years, parallel imaging, temporal encoding and compressed…

The task of medical image segmentation commonly involves an image reconstruction step to convert acquired raw data to images before any analysis. However, noises, artifacts and loss of information due to the reconstruction process are…

Computer Vision and Pattern Recognition · Computer Science 2019-07-23 Qiaoying Huang , Xiao Chen , Dimitris Metaxas , Mariappan S. Nadar

Magnetic resonance imaging (MRI) reconstruction is an active inverse problem which can be addressed by conventional compressed sensing (CS) MRI algorithms that exploit the sparse nature of MRI in an iterative optimization-based manner.…

Computer Vision and Pattern Recognition · Computer Science 2019-06-13 Yuxiang Dai , Peixian Zhuang

Image reconstruction from undersampled k-space data has been playing an important role for fast MRI. Recently, deep learning has demonstrated tremendous success in various fields and also shown potential to significantly speed up MR…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Dong Liang , Jing Cheng , Ziwen Ke , Leslie Ying

Deciphering how visual stimuli are transformed into cortical responses is a fundamental challenge in computational neuroscience. This visual-to-neural mapping is inherently a one-to-many relationship, as identical visual inputs reliably…

Machine Learning · Computer Science 2025-11-04 Weijian Mai , Jiamin Wu , Yu Zhu , Zhouheng Yao , Dongzhan Zhou , Andrew F. Luo , Qihao Zheng , Wanli Ouyang , Chunfeng Song

Automated sample preparation and electron microscopy enables acquisition of very large image data sets. These technical advances are of special importance to the field of neuroanatomy, as 3D reconstructions of neuronal processes at the nm…

Functional magnetic resonance imaging (fMRI) is a powerful tool for investigating human brain function. However, the high cost of data acquisition and the inherent subjectivity of psychiatric rating scales often lead to datasets with small…

Machine Learning · Computer Science 2026-05-29 Jiyao Wang , Peiyu Duan , Nicha C. Dvornek , Lawrence H. Staib , Denis Sukhodolsky , Pamela Ventola , James S. Duncan

Neuroradiologists and neurosurgeons increasingly opt to use functional magnetic resonance imaging (fMRI) to map functionally relevant brain regions for noninvasive presurgical planning and intraoperative neuronavigation. This application…

Methodology · Statistics 2023-06-07 Andrew S. Whiteman , Andreas J. Bartsch , Jian Kang , Timothy D. Johnson

Functional Magnetic Resonance Imaging (fMRI) relies on multi-step data processing pipelines to accurately determine brain activity; among them, the crucial step of spatial smoothing. These pipelines are commonly suboptimal, given the local…

Computer Vision and Pattern Recognition · Computer Science 2017-10-03 Albert Vilamala , Kristoffer Hougaard Madsen , Lars Kai Hansen

Image stacks provide invaluable 3D information in various biological and pathological imaging applications. Fourier ptychographic microscopy (FPM) enables reconstructing high-resolution, wide field-of-view image stacks without z-stack…

The human brain is a complex system requiring both macroscopic and microscopic components for comprehensive understanding. However, mapping nonlinear relationships between these scales remains challenging due to technical limitations and…

Image and Video Processing · Electrical Eng. & Systems 2025-10-28 Sooyoung Kim , Joonwoo Kwon , Junbeom Kwon , Jungyoun Janice Min , Sangyoon Bae , Yuewei Lin , Shinjae Yoo , Jiook Cha

Backpropagation is the core learning mechanism underlying deep learning. However, whether and how this algorithm is implemented in the brain remains highly debated. In particular, while forward activations of pretrained models reliably map…

Here, we present a novel approach to solve the problem of reconstructing perceived stimuli from brain responses by combining probabilistic inference with deep learning. Our approach first inverts the linear transformation from latent…

Neurons and Cognition · Quantitative Biology 2017-06-16 Yağmur Güçlütürk , Umut Güçlü , Katja Seeliger , Sander Bosch , Rob van Lier , Marcel van Gerven

Following the success of deep learning in a wide range of applications, neural network-based machine learning techniques have received interest as a means of accelerating magnetic resonance imaging (MRI). A number of ideas inspired by deep…

Signal Processing · Electrical Eng. & Systems 2019-04-03 Florian Knoll , Kerstin Hammernik , Chi Zhang , Steen Moeller , Thomas Pock , Daniel K. Sodickson , Mehmet Akcakaya

Recent progress in visual brain decoding from fMRI has been enabled by large-scale datasets such as the Natural Scenes Dataset (NSD) and powerful diffusion-based generative models. While current pipelines are primarily optimized for…

Neurons and Cognition · Quantitative Biology 2026-04-20 Fabrizio Spera , Tommaso Boccato , Michal Olak , Sara Cammarota , Matteo Ciferri , Michelangelo Tronti , Nicola Toschi , Matteo Ferrante