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Approximate Bayesian Computation is widely used in systems biology for inferring parameters in stochastic gene regulatory network models. Its performance hinges critically on the ability to summarize high-dimensional system responses such…

Machine Learning · Statistics 2021-04-13 Mattias Åkesson , Prashant Singh , Fredrik Wrede , Andreas Hellander

We propose a new methodology for parameterized constrained robust optimization, an important class of optimization problems under uncertainty, based on learning with a self-supervised penalty-based loss function. Whereas supervised learning…

Optimization and Control · Mathematics 2025-03-10 Wyame Benslimane , Paul Grigas

The human brain utilizes spikes for information transmission and dynamically reorganizes its network structure to boost energy efficiency and cognitive capabilities throughout its lifespan. Drawing inspiration from this spike-based…

Human-Computer Interaction · Computer Science 2025-02-20 Jiangrong Shen , Qi Xu , Gang Pan , Badong Chen

Consider observing a collection of discrete events within a network that reflect how network nodes influence one another. Such data are common in spike trains recorded from biological neural networks, interactions within a social network,…

Machine Learning · Statistics 2018-02-15 Benjamin Mark , Garvesh Raskutti , Rebecca Willett

Parameter estimation in structural dynamics generally involves inferring the values of physical, geometric, or even customized parameters based on first principles or expert knowledge, which is challenging for complex structural systems. In…

Computational Engineering, Finance, and Science · Computer Science 2025-04-08 Mingyuan Zhou , Haoze Song , Wenjing Ye , Wei Wang , Zhilu Lai

Although evidence integration to the boundary model has successfully explained a wide range of behavioral and neural data in decision making under uncertainty, how animals learn and optimize the boundary remains unresolved. Here, we propose…

Neural and Evolutionary Computing · Computer Science 2024-08-13 Jamal Esmaily , Rani Moran , Yasser Roudi , Bahador Bahrami

In many economically relevant contexts where machine learning is deployed, multiple platforms obtain data from the same pool of users, each of whom selects the platform that best serves them. Prior work in this setting focuses exclusively…

Machine Learning · Computer Science 2026-03-02 Adhyyan Narang , Sarah Dean , Lillian J Ratliff , Maryam Fazel

Spiking Neural Networks (SNNs) are biologically inspired machine learning models that build on dynamic neuronal models processing binary and sparse spiking signals in an event-driven, online, fashion. SNNs can be implemented on neuromorphic…

Neural and Evolutionary Computing · Computer Science 2020-12-10 Hyeryung Jang , Nicolas Skatchkovsky , Osvaldo Simeone

Simulation-Grounded Neural Networks (SGNNs) are predictive models trained entirely on synthetic data from mechanistic simulations. They have achieved state-of-the-art performance in domains where real-world labels are limited or unobserved,…

Machine Learning · Computer Science 2025-10-03 Carson Dudley , Marisa Eisenberg

We introduce a method for automatically selecting the path, or syllabus, that a neural network follows through a curriculum so as to maximise learning efficiency. A measure of the amount that the network learns from each data sample is…

Neural and Evolutionary Computing · Computer Science 2017-04-12 Alex Graves , Marc G. Bellemare , Jacob Menick , Remi Munos , Koray Kavukcuoglu

Spiking Neural Networks are powerful computational modelling tools that have attracted much interest because of the bioinspired modelling of synaptic interactions between neurons. Most of the research employing spiking neurons has been…

Neural and Evolutionary Computing · Computer Science 2019-03-05 Huanneng Qiu , Matthew Garratt , David Howard , Sreenatha Anavatti

We initiate the study of biological neural networks from the perspective of streaming algorithms. Like computers, human brains suffer from memory limitations which pose a significant obstacle when processing large scale and dynamically…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-06 Yael Hitron , Cameron Musco , Merav Parter

An important characteristic of neural networks is their ability to learn representations of the input data with effective features for prediction, which is believed to be a key factor to their superior empirical performance. To better…

Machine Learning · Computer Science 2022-06-06 Zhenmei Shi , Junyi Wei , Yingyu Liang

Most normative models in computational neuroscience describe the task of learning as the optimisation of a cost function with respect to a set of parameters. However, learning as optimisation fails to account for a time varying environment…

Neurons and Cognition · Quantitative Biology 2020-08-10 Jannes Jegminat , Jean-Pascal Pfister

This work applies concepts of artificial neural networks to identify the parameters of a mathematical model based on phase fields for damage and fracture. Damage mechanics is the part of the continuum mechanics that models the effects of…

Materials Science · Physics 2021-07-21 Carlos J. G. Rojas , Marco L. Bitterncourt , José L. Boldrini

To understand how rich dynamics emerge in neural populations, we require models exhibiting a wide range of activity patterns while remaining interpretable in terms of connectivity and single-neuron dynamics. However, it has been challenging…

Neurons and Cognition · Quantitative Biology 2020-03-10 Alexandre René , André Longtin , Jakob H. Macke

Simulation is a useful tool in situations where training data for machine learning models is costly to annotate or even hard to acquire. In this work, we propose a reinforcement learning-based method for automatically adjusting the…

Machine Learning · Computer Science 2019-05-15 Nataniel Ruiz , Samuel Schulter , Manmohan Chandraker

Microstructural evolution is a key aspect of understanding and exploiting the structure-property-performance relation of materials. Modeling microstructure evolution usually relies on coarse-grained simulations with evolution principles…

Materials Science · Physics 2020-09-01 Kaiqi Yang , Yifan Cao , Youtian Zhang , Ming Tang , Daniel Aberg , Babak Sadigh , Fei Zhou

Applications that generate huge amounts of data in the form of fast streams are becoming increasingly prevalent, being therefore necessary to learn in an online manner. These conditions usually impose memory and processing time…

Neural and Evolutionary Computing · Computer Science 2019-08-22 Jesus L. Lobo , Javier Del Ser , Albert Bifet , Nikola Kasabov

We present a theoretical study aiming at model fitting for sensory neurons. Conventional neural network training approaches are not applicable to this problem due to lack of continuous data. Although the stimulus can be considered as a…

Neurons and Cognition · Quantitative Biology 2017-09-28 R. Ozgur Doruk , Kechen Zhang
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