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The processes taking place inside the living cell are now understood to the point where predictive computational models can be used to gain detailed understanding of important biological phenomena. A key challenge is to extrapolate this…

Tissues and Organs · Quantitative Biology 2018-10-26 Stefan Engblom Daniel B. Wilson , Ruth E. Baker

Conditional medical image generation plays an important role in many clinically relevant imaging tasks. However, existing methods still face a fundamental challenge in balancing inference efficiency, patient-specific fidelity, and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Zirong Li , Siyuan Mei , Weiwen Wu , Andreas Maier , Lina Gölz , Yan Xia

In recent years hypergraphs have emerged as a powerful tool to study systems with multi-body interactions which cannot be trivially reduced to pairs. While highly structured methods to generate synthetic data have proved fundamental for the…

Social and Information Networks · Computer Science 2024-10-10 Nicolò Ruggeri , Federico Battiston , Caterina De Bacco

To make 3D human avatars widely available, we must be able to generate a variety of 3D virtual humans with varied identities and shapes in arbitrary poses. This task is challenging due to the diversity of clothed body shapes, their complex…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Xu Chen , Tianjian Jiang , Jie Song , Jinlong Yang , Michael J. Black , Andreas Geiger , Otmar Hilliges

Noninvasive reconstruction of cardiac transmembrane potential (TMP) from surface electrocardiograms (ECG) involves an ill-posed inverse problem. Model-constrained regularization is powerful for incorporating rich physiological knowledge…

Image and Video Processing · Electrical Eng. & Systems 2019-05-14 Sandesh Ghimire , Jwala Dhamala , Prashnna Kumar Gyawali , John L Sapp , B. Milan Horacek , Linwei Wang

Background: Heart failure (HF) research is constrained by limited access to large, shareable datasets due to privacy regulations and institutional barriers. Synthetic data generation offers a promising solution to overcome these challenges…

The shape of many objects in the built environment is dictated by their relationships to the human body: how will a person interact with this object? Existing data-driven generative models of 3D shapes produce plausible objects but do not…

Graphics · Computer Science 2022-01-24 Bryce Blinn , Alexander Ding , R. Kenny Jones , Manolis Savva , Srinath Sridhar , Daniel Ritchie

Anatomy shape modeling is a fundamental problem in medical data analysis. However, the geometric complexity and topological variability of anatomical structures pose significant challenges to accurate anatomical shape generation. In this…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Guoqing Zhang , Jingyun Yang , Siqi Chen , Anping Zhang , Yang Li

This work investigates whether time series of natural phenomena can be understood as being generated by sequences of latent states which are ordered in systematic and regular ways. We focus on clinical time series and ask whether clinical…

Machine Learning · Computer Science 2025-08-29 Michael Hagmann , Michael Staniek , Stefan Riezler

We introduce materiomusic as a generative framework linking the hierarchical structures of matter with the compositional logic of music. Across proteins, spider webs and flame dynamics, vibrational and architectural principles recur as…

Machine Learning · Computer Science 2026-01-06 Markus J. Buehler

Augmentation by generative modelling yields a promising alternative to the accumulation of surgical data, where ethical, organisational and regulatory aspects must be considered. Yet, the joint synthesis of (image, mask) pairs for…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Yannik Frisch , Christina Bornberg , Moritz Fuchs , Anirban Mukhopadhyay

Currently, a central challenge and bottleneck in the deployment and validation of computer-aided diagnosis (CAD) models within the field of medical imaging is data scarcity. For lung cancer, one of the most prevalent types worldwide,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 António Cardoso , Pedro Sousa , Tania Pereira , Hélder P. Oliveira

We present a novel framework that learns to predict human anatomy from body surface. Specifically, our approach generates a synthetic X-ray image of a person only from the person's surface geometry. Furthermore, the synthetic X-ray image is…

Computer Vision and Pattern Recognition · Computer Science 2018-05-15 Brian Teixeira , Vivek Singh , Terrence Chen , Kai Ma , Birgi Tamersoy , Yifan Wu , Elena Balashova , Dorin Comaniciu

Effectively medication recommendation with complex multimorbidity conditions is a critical task in healthcare. Most existing works predicted medications based on longitudinal records, which assumed the information transmitted patterns of…

Machine Learning · Computer Science 2023-09-13 Sicen Liu , Xiaolong Wang , JIngcheng Du , Yongshuai Hou , Xianbing Zhao , Hui Xu , Hui Wang , Yang Xiang , Buzhou Tang

Facial composites are graphical representations of an eyewitness's memory of a face. Many digital systems are available for the creation of such composites but are either unable to reproduce features unless previously designed or do not…

Computer Vision and Pattern Recognition · Computer Science 2019-12-12 Nicola Zaltron , Luisa Zurlo , Sebastian Risi

Biomarker discovery is vital in advancing personalized medicine, offering insights into disease diagnosis, prognosis, and therapeutic efficacy. Traditionally, the identification and validation of biomarkers heavily depend on extensive…

Machine Learning · Computer Science 2024-09-25 Wangyang Ying , Dongjie Wang , Xuanming Hu , Ji Qiu , Jin Park , Yanjie Fu

Recent advances in generative AI offer promising solutions for synthetic data generation but often rely on large datasets for effective training. To address this limitation, we propose a novel generative model that learns from limited data…

Machine Learning · Statistics 2025-05-27 Michail Spitieris , Massimiliano Ruocco , Abdulmajid Murad , Alessandro Nocente

Based on a combined data set of 4000 high resolution facial scans, we introduce a non-linear morphable face model, capable of producing multifarious face geometry of pore-level resolution, coupled with material attributes for use in…

Computer Vision and Pattern Recognition · Computer Science 2020-04-27 Ruilong Li , Karl Bladin , Yajie Zhao , Chinmay Chinara , Owen Ingraham , Pengda Xiang , Xinglei Ren , Pratusha Prasad , Bipin Kishore , Jun Xing , Hao Li

In recent years, convolutional neural networks have demonstrated promising performance in a variety of medical image segmentation tasks. However, when a trained segmentation model is deployed into the real clinical world, the model may not…

Image and Video Processing · Electrical Eng. & Systems 2020-12-24 Shuo Wang , Giacomo Tarroni , Chen Qin , Yuanhan Mo , Chengliang Dai , Chen Chen , Ben Glocker , Yike Guo , Daniel Rueckert , Wenjia Bai

Anatomy evaluation is crucial for understanding the physiological state, diagnosing abnormalities, and guiding medical interventions. Statistical shape modeling (SSM) is vital in this process. By enabling the extraction of quantitative…

Computer Vision and Pattern Recognition · Computer Science 2025-02-12 Krithika Iyer , Mokshagna Sai Teja Karanam , Shireen Elhabian