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Data-driven generative modeling has made remarkable progress by leveraging the power of deep neural networks. A reoccurring challenge is how to enable a model to generate a rich variety of samples from the entire target distribution, rather…

Graphics · Computer Science 2019-09-04 Nadav Schor , Oren Katzir , Hao Zhang , Daniel Cohen-Or

Generative modeling of anatomical structures plays a crucial role in virtual imaging trials, which allow researchers to perform studies without the costs and constraints inherent to in vivo and phantom studies. For clinical relevance,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Bram de Wilde , Max T. Rietberg , Guillaume Lajoinie , Jelmer M. Wolterink

Generative modelling for shapes is a prerequisite for In-Silico Clinical Trials (ISCTs), which aim to cost-effectively validate medical device interventions using synthetic anatomical shapes, often represented as 3D surface meshes. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Soodeh Kalaie , Andy Bulpitt , Alejandro F. Frangi , Ali Gooya

Sequential assembly with geometric primitives has drawn attention in robotics and 3D vision since it yields a practical blueprint to construct a target shape. However, due to its combinatorial property, a greedy method falls short of…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Jungtaek Kim , Hyunsoo Chung , Jinhwi Lee , Minsu Cho , Jaesik Park

Congenital heart disease (CHD) encompasses a spectrum of cardiovascular structural abnormalities, often requiring customized treatment plans for individual patients. Computational modeling and analysis of these unique cardiac anatomies can…

Tissues and Organs · Quantitative Biology 2023-11-09 Fanwei Kong , Sascha Stocker , Perry S. Choi , Michael Ma , Daniel B. Ennis , Alison Marsden

Personalized image generative models are highly proficient at synthesizing images from text or a single image, yet they lack explicit control for composing objects from specific parts of multiple source images without user specified masks…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Shivam Singh , Yiming Chen , Agneet Chatterjee , Amit Raj , James Hays , Yezhou Yang , Chitta Baral

In this work, we propose a composition/decomposition framework for adversarially training generative models on composed data - data where each sample can be thought of as being constructed from a fixed number of components. In our…

Machine Learning · Computer Science 2019-01-24 Yeu-Chern Harn , Zhenghao Chen , Vladimir Jojic

Generating datasets that "look like" given real ones is an interesting tasks for healthcare applications of ML and many other fields of science and engineering. In this paper we propose a new method of general application to binary datasets…

Machine Learning · Statistics 2018-07-05 Laura Aviñó , Matteo Ruffini , Ricard Gavaldà

Image translation across domains for unpaired datasets has gained interest and great improvement lately. In medical imaging, there are multiple imaging modalities, with very different characteristics. Our goal is to use cross-modality…

Image and Video Processing · Electrical Eng. & Systems 2022-02-07 Leo Segre , Or Hirschorn , Dvir Ginzburg , Dan Raviv

The generation of virtual populations (VPs) of anatomy is essential for conducting in silico trials of medical devices. Typically, the generated VP should capture sufficient variability while remaining plausible and should reflect the…

Image and Video Processing · Electrical Eng. & Systems 2023-07-31 Haoran Dou , Nishant Ravikumar , Alejandro F. Frangi

Deep learning models for chest X-ray diagnosis are constrained by limited coverage of clinically meaningful concept combinations in publicly available training datasets. While synthetic image generation has been explored to increase data…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Amy Rafferty , Rishi Ramaesh , Ajitha Rajan

Generative modeling has recently seen many exciting developments with the advent of deep generative architectures such as Variational Auto-Encoders (VAE) or Generative Adversarial Networks (GAN). The ability to draw synthetic i.i.d.…

Machine Learning · Computer Science 2021-02-19 Johan Leduc , Nicolas Grislain

We present GenMM, a generative model that "mines" as many diverse motions as possible from a single or few example sequences. In stark contrast to existing data-driven methods, which typically require long offline training time, are prone…

Graphics · Computer Science 2023-06-02 Weiyu Li , Xuelin Chen , Peizhuo Li , Olga Sorkine-Hornung , Baoquan Chen

Quantification of anatomical shape changes currently relies on scalar global indexes which are largely insensitive to regional or asymmetric modifications. Accurate assessment of pathology-driven anatomical remodeling is a crucial step for…

Research in vertebral bone micro-structure generally requires costly procedures to obtain physical scans of real bone with a specific pathology under study, since no methods are available yet to generate realistic bone structures in-silico.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-25 Emmanuel Iarussi , Felix Thomsen , Claudio Delrieux

An ideal synthetic population, a key input to activity-based models, mimics the distribution of the individual- and household-level attributes in the actual population. Since the entire population's attributes are generally unavailable,…

Machine Learning · Statistics 2022-08-03 Eui-Jin Kim , Prateek Bansal

We present a probabilistic 3D generative model, named Generative Cellular Automata, which is able to produce diverse and high quality shapes. We formulate the shape generation process as sampling from the transition kernel of a Markov…

Computer Vision and Pattern Recognition · Computer Science 2021-03-09 Dongsu Zhang , Changwoon Choi , Jeonghwan Kim , Young Min Kim

Methods that use neural networks for synthesizing 3D shapes in the form of a part-based representation have been introduced over the last few years. These methods represent shapes as a graph or hierarchy of parts and enable a variety of…

Graphics · Computer Science 2024-09-20 Yanran Guan , Oliver van Kaick

This paper presents a comprehensive systematic review of generative models (GANs, VAEs, DMs, and LLMs) used to synthesize various medical data types, including imaging (dermoscopic, mammographic, ultrasound, CT, MRI, and X-ray), text,…

Human anatomy, morphology, and associated diseases can be studied using medical imaging data. However, access to medical imaging data is restricted by governance and privacy concerns, data ownership, and the cost of acquisition, thus…

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