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This paper presents DeepFLASH, a novel network with efficient training and inference for learning-based medical image registration. In contrast to existing approaches that learn spatial transformations from training data in the high…

Image and Video Processing · Electrical Eng. & Systems 2020-04-07 Jian Wang , Miaomiao Zhang

Purpose: To develop an algorithm for real-time volumetric image reconstruction and 3D tumor localization based on a single x-ray projection image for lung cancer radiotherapy. Methods: Given a set of volumetric images of a patient at N…

Medical Physics · Physics 2015-05-18 Ruijiang Li , Xun Jia , John H. Lewis , Xuejun Gu , Michael Folkerts , Chunhua Men , Steve B. Jiang

Due to the inter- and intra- variation of respiratory motion, it is highly desired to provide real-time volumetric images during the treatment delivery of lung stereotactic body radiation therapy (SBRT) for accurate and active motion…

We propose Deep-Motion-Net: an end-to-end graph neural network (GNN) architecture that enables 3D (volumetric) organ shape reconstruction from a single in-treatment kV planar X-ray image acquired at any arbitrary projection angle.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Isuru Wijesinghe , Michael Nix , Arezoo Zakeri , Alireza Hokmabadi , Bashar Al-Qaisieh , Ali Gooya , Zeike A. Taylor

Radiotherapy (RT) is a critical cancer treatment, with volumetric modulated arc therapy (VMAT) being a commonly used technique that enhances dose conformity by dynamically adjusting multileaf collimator (MLC) positions and monitor units…

Medical Physics · Physics 2025-06-26 Stefanos Achlatis , Efstratios Gavves , Jan-Jakob Sonke

Purpose: The FLASH effect, which reduces the radiosensitivity of healthy tissue while maintaining tumor control at high dose rates, has shown potential for improving radiation therapy. Conformal FLASH proton therapy involves advanced…

Medical Physics · Physics 2023-04-13 Sylvain Deffet , Edmond Sterpin

We propose a novel deep-learning framework for super-resolution ultrasound images and videos in terms of spatial resolution and line reconstruction. We up-sample the acquired low-resolution image through a vision-based interpolation method;…

Computer Vision and Pattern Recognition · Computer Science 2023-05-03 Simone Cammarasana , Paolo Nicolardi , Giuseppe Patanè

Treatment planning is currently a patient specific, time-consuming, and resource demanding task in radiotherapy. Dose-volume histogram (DVH) prediction plays a critical role in automating this process. The geometric relationship between…

Artificial Intelligence · Computer Science 2024-02-13 Zehao Dong , Yixin Chen , Hiram Gay , Yao Hao , Geoffrey D. Hugo , Pamela Samson , Tianyu Zhao

Purpose: In some proton therapy facilities, patient alignment relies on two 2D orthogonal kV images, taken at fixed, oblique angles, as no 3D on-the-bed imaging is available. The visibility of the tumor in kV images is limited since the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-19 Yuzhen Ding , Hongying Feng , Yunze Yang , Jason Holmes , Zhengliang Liu , David Liu , William W. Wong , Nathan Y. Yu , Terence T. Sio , Steven E. Schild , Baoxin Li , Wei Liu

Purpose: The purpose of this work was to provide a flexible platform for FLASH research with protons by adapting a former clinical pencil beam scanning gantry to irradiations with ultrahigh dose rates. Methods: PSI Gantry 1 treated patients…

We investigated the effects of scanning speed, beam configuration, and dose-rate modeling on the FLASH effect in post-mastectomy proton transmission-beam (TB) planning and evaluated whether optimizing the spot-scanning path can enhance…

Dose-Volume Histogram (DVH) prediction is fundamental in radiation therapy that facilitate treatment planning, dose evaluation, plan comparison and etc. It helps to increase the ability to deliver precise and effective radiation treatments…

Machine Learning · Computer Science 2024-02-05 Zehao Dong , Yixin Chen , Tianyu Zhao

The objective of this study was to develop a PET tumor-segmentation framework that addresses the challenges of limited spatial resolution, high image noise, and lack of clinical training data with ground-truth tumor boundaries in PET…

FLASH is a new treatment modality that requires optimization of dose, dose rate, and LET. Here we validate these three quantities under FLASH conditions, which includes the quantum uncertainty in the time-dependent instantaneous dose rate…

Early detection of lung cancer is crucial for effective treatment and relies on accurate volumetric assessment of pulmonary nodules in CT scans. Traditional methods, such as consolidation-to-tumor ratio (CTR) and spherical approximation,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Yihan Zhou , Haocheng Huang , Yue Yu , Jianhui Shang

Contemporary interventional imaging lacks the real-time 3D guidance needed for the precise localization of mobile thoracic targets. While Cone-Beam CT (CBCT) provides 3D data, it is often too slow for dynamic motion tracking. Deep learning…

Medical Physics · Physics 2025-11-19 Fawazilla Utomo , Tess Reynolds , Nicholas Hindley

Super-resolution is widely used in medical imaging to enhance low-quality data, reducing scan time and improving abnormality detection. Conventional super-resolution approaches typically rely on paired datasets of downsampled and original…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Xiaoyi Wen , Fei Jiang

Mesh reconstruction is a cornerstone process across various applications, including in-silico trials, digital twins, surgical planning, and navigation. Recent advancements in deep learning have notably enhanced mesh reconstruction speeds.…

Image and Video Processing · Electrical Eng. & Systems 2025-05-22 Fengting Zhang , Boxu Liang , Qinghao Liu , Min Liu , Xiang Chen , Yaonan Wang

Synchrotron-based X-ray computed tomography is widely used for investigating inner structures of specimens at high spatial resolutions. However, potential beam damage to samples often limits the X-ray exposure during tomography experiments.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-30 Ziling Wu , Tekin Bicer , Zhengchun Liu , Vincent De Andrade , Yunhui Zhu , Ian T. Foster

We present a Machine Learning-based method for tomographic reconstruction of dense layered objects, with range of projection angles limited to $\pm $10$^\circ$. Whereas previous approaches to phase tomography generally require two steps,…

Image and Video Processing · Electrical Eng. & Systems 2020-01-08 Alexandre Goy , Girish Rughoobur , Shuai Li , Kwabena Arthur , Akintunde I. Akinwande , George Barbastathis
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