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This paper focuses on and analyzes realistic SIR models that take stochasticity into account. The proposed systems are applicable to most incidence rates that are used in the literature including the bilinear incidence rate, the…

Probability · Mathematics 2024-07-10 Nguyen Du , Alexandru Hening , Nhu Nguyen , George Yin

We study a susceptible-infected-recovered (SIR) epidemic model on a network of $n$ interacting subpopulations. We analyze the transient and asymptotic behavior of the infection dynamics in each node of the network. In contrast to the…

Dynamical Systems · Mathematics 2024-03-18 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani

Epidemic control is of great importance for human society. Adjusting interacting partners is an effective individualized control strategy. Intuitively, it is done either by shortening the interaction time between susceptible and infected…

Populations and Evolution · Quantitative Biology 2016-12-28 Bin Wu , Shanjun Mao , Jiazeng Wang , Da Zhou

An investigation was conducted to study the robustness of the results obtained from the cellular automata model which describes the spread of the HIV infection within lymphoid tissues [R. M. Zorzenon dos Santos and S. Coutinho, Phys. Rev.…

Biological Physics · Physics 2008-07-21 P. H. Figueirêdo , S. Coutinho , R. M. Zorzenon dos Santos

An actively controlled Susceptible-Infected-Susceptible (actSIS) contagion model is presented for studying epidemic dynamics with continuous-time feedback control of infection rates. Our work is inspired by the observation that epidemics…

Physics and Society · Physics 2020-07-06 Yunxiu Zhou , Simon A. Levin , Naomi E. Leonard

We consider the dynamics of a population of organisms containing two mutually inhibitory gene regulatory networks, that can result in a bistable switch-like behaviour. We completely characterize their local and global dynamics in the…

Molecular Networks · Quantitative Biology 2016-10-07 Michael C. Mackey , Marta Tyran-Kaminska

Mathematical models are formal and simplified representations of the knowledge related to a phenomenon. In classical epidemic models, a neglected aspect is the heterogeneity of disease transmission and progression linked to the viral load…

Physics and Society · Physics 2022-05-10 Rossella Della Marca , Nadia Loy , Andrea Tosin

An epidemic model with distributed time delay is derived to describe the dynamics of infectious diseases with varying immunity. It is shown that solutions are always positive, and the model has at most two steady states: disease-free and…

Chaotic Dynamics · Physics 2012-09-21 K. B. Blyuss , Y. N. Kyrychko

An epidemic model, where the dispersal is approximated by nonlocal diffusion operator and spatial domain has one ?xed boundary and one free boundary, is considered in this paper. Firstly, using some elementary analysis instead of…

Analysis of PDEs · Mathematics 2024-05-08 Lei Li , Mingxin Wang

In recent years, classical epidemic models, which assume stationary behavior of individuals, have been extended to include an adaptive heterogeneous response of the population to the current state of the epidemic. However, it is widely…

Dynamical Systems · Mathematics 2022-01-19 Ruofei Guan , Jana Kopfová , Dmitrii Rachinskii

We consider a spatially-heterogeneous generalization of a well-established model for the dynamics of the Human Immunodeficiency Virus-type 1 (HIV) within a susceptible host. The model consists of a nonlinear system of three coupled…

Analysis of PDEs · Mathematics 2016-04-18 Stephen Pankavich , Christian Parkinson

The dynamics of strongly immunizing childhood infections is still not well understood. Although reports of successful modeling of several incidence data records can be found in the literature, the key determinants of the observed temporal…

Populations and Evolution · Quantitative Biology 2012-10-09 Ganna Rozhnova , Ana Nunes

Despite the enormous relevance of zoonotic infections to world- wide public health, and despite much effort in modeling individual zoonoses, a fundamental understanding of the disease dynamics and the nature of outbreaks arising in such…

Populations and Evolution · Quantitative Biology 2013-07-18 Sarabjeet Singh , David J. Schneider , Christopher R. Myers

Random walks and related spatial stochastic models have been used in a range of application areas including animal and plant ecology, infectious disease epidemiology, developmental biology, wound healing, and oncology. Classical random walk…

Populations and Evolution · Quantitative Biology 2025-08-22 Michael J. Plank , Matthew J. Simpson , Ruth E. Baker

Existing approaches to modelling antibody concentration data are mostly based on finite mixture models that rely on the assumption that individuals can be divided into two distinct groups: seronegative and seropositive. Here, we challenge…

Methodology · Statistics 2026-04-20 Emanuele Giorgi , Jonas Wallin

Waning immunity and reinfection are critical features of many infectious diseases, but epidemiological models often fail to capture the intricate interaction between an individual's history of immunity and their current infection status;…

Populations and Evolution · Quantitative Biology 2026-03-25 Raimund M. Kovacevic , Nikolaos I. Stilianakis , Vladimir M. Veliov

In this paper, a stochastic Gilpin-Ayala population model with regime switching and white noise is considered. All parameters are influenced by stochastic perturbations. The existence of global positive solution, asymptotic stability in…

Probability · Mathematics 2018-10-31 Kai Wang , Yanling Zhu

This paper studies the dynamics of a network-based SIRS epidemic model with vaccination and a nonmonotone incidence rate. This type of nonlinear incidence can be used to describe the psychological or inhibitory effect from the behavioral…

Populations and Evolution · Quantitative Biology 2018-11-14 Lijun Liu , Xiaodan Wei , Naimin Zhang

Cholera, a severe gastrointestinal infection caused by the bacterium Vibrio cholerae, remains a major threat to public health with a yearly estimated global burden of 2.9 million cases. Although the majority of existing models for the…

Dynamical Systems · Mathematics 2021-05-27 Beryl Musundi

We study the asymptotic behavior of stationary solutions to a quantitative genetics model with trait-dependent mortality and sexual reproduction. The infinitesimal model accounts for the mixing of parental phenotypes at birth.Our asymptotic…

Analysis of PDEs · Mathematics 2019-08-29 Vincent Calvez , Jimmy Garnier , Florian Patout
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