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\textbf{Motivation:} Predicting single-cell perturbation responses requires mapping between two unpaired single-cell data distributions. Optimal transport (OT) theory provides a principled framework for constructing such mappings by…

Machine Learning · Computer Science 2025-04-22 Yanshuo Chen , Zhengmian Hu , Wei Chen , Heng Huang

Operator regression provides a powerful means of constructing discretization-invariant emulators for partial-differential equations (PDEs) describing physical systems. Neural operators specifically employ deep neural networks to approximate…

Machine Learning · Computer Science 2023-04-18 Katiana Kontolati , Somdatta Goswami , George Em Karniadakis , Michael D. Shields

Wasserstein distance (WD) and the associated optimal transport plan have been proven useful in many applications where probability measures are at stake. In this paper, we propose a new proxy of the squared WD, coined min-SWGG, that is…

Machine Learning · Statistics 2023-10-31 Guillaume Mahey , Laetitia Chapel , Gilles Gasso , Clément Bonet , Nicolas Courty

Optimal transport is widely used to learn distributions, enforce distributional constraints, and model uncertainty. In applications, transport losses are often computed from samples through tractable representations, such as one-dimensional…

Optimization and Control · Mathematics 2026-05-28 Tam Le

Singularly perturbed problems present inherent difficulty due to the presence of a thin boundary layer in its solution. To overcome this difficulty, we propose using deep operator networks (DeepONets), a method previously shown to be…

Numerical Analysis · Mathematics 2023-06-30 Ting Du , Zhongyi Huang , Ye Li

Uncertainty and delayed reactions in human driving behavior lead to stop-and-go traffic congestion on freeways. The freeway traffic dynamics are governed by the Aw-Rascle-Zhang (ARZ) traffic Partial Differential Equation (PDE) models with…

Optimization and Control · Mathematics 2025-09-29 Kaijing Lv , Junmin Wang , Yihuai Zhang , Huan Yu

In this paper, we evaluate the effectiveness of deep operator networks (DeepONets) in solving both forward and inverse problems of partial differential equations (PDEs) on unknown manifolds. By unknown manifolds, we identify the manifold by…

Numerical Analysis · Mathematics 2024-07-09 Anran Jiao , Qile Yan , Jhn Harlim , Lu Lu

In machine learning, Optimal Transport (OT) theory is extensively utilized to compare probability distributions across various applications, such as graph data represented by node distributions and image data represented by pixel…

Machine Learning · Computer Science 2025-01-30 Jianming Huang , Xun Su , Zhongxi Fang , Hiroyuki Kasai

We consider a general online stochastic optimization problem with multiple budget constraints over a horizon of finite time periods. In each time period, a reward function and multiple cost functions are revealed, and the decision maker…

Machine Learning · Computer Science 2022-07-26 Jiashuo Jiang , Xiaocheng Li , Jiawei Zhang

The use of optimal transport cost for learning generative models has become popular with Wasserstein Generative Adversarial Networks (WGAN). Training of WGAN relies on a theoretical background: the calculation of the gradient of the optimal…

Machine Learning · Statistics 2024-04-04 Antoine Houdard , Arthur Leclaire , Nicolas Papadakis , Julien Rabin

Adapting large-scale foundation models to new domains with limited supervision remains a fundamental challenge due to latent distribution mismatch, unstable optimization dynamics, and miscalibrated uncertainty propagation. This paper…

Machine Learning · Computer Science 2026-03-27 Aueaphum Aueawatthanaphisut , Kuepon Auewattanapisut

Generative Adversial Networks (GANs) have made a major impact in computer vision and machine learning as generative models. Wasserstein GANs (WGANs) brought Optimal Transport (OT) theory into GANs, by minimizing the $1$-Wasserstein distance…

Machine Learning · Computer Science 2019-02-12 Anton Mallasto , Jes Frellsen , Wouter Boomsma , Aasa Feragen

Full Waveform Inversion (FWI) is an important geophysical technique considered in subsurface property prediction. It solves the inverse problem of predicting high-resolution Earth interior models from seismic data. Traditional FWI methods…

Multi-task learning (MTL) is an inductive transfer mechanism designed to leverage useful information from multiple tasks to improve generalization performance compared to single-task learning. It has been extensively explored in traditional…

Machine Learning · Computer Science 2025-01-13 Varun Kumar , Somdatta Goswami , Katiana Kontolati , Michael D. Shields , George Em Karniadakis

The deep operator networks (DeepONet), a class of neural operators that learn mappings between function spaces, have recently been developed as surrogate models for parametric partial differential equations (PDEs). In this work we propose a…

Machine Learning · Computer Science 2024-10-31 Yuan Qiu , Nolan Bridges , Peng Chen

In the realm of computational science and engineering, constructing models that reflect real-world phenomena requires solving partial differential equations (PDEs) with different conditions. Recent advancements in neural operators, such as…

Quantum Physics · Physics 2025-06-11 Pengpeng Xiao , Muqing Zheng , Anran Jiao , Xiu Yang , Lu Lu

Deep neural networks (DNNs) often produce overconfident predictions on out-of-distribution (OOD) inputs, undermining their reliability in open-world environments. Singularities in semi-discrete optimal transport (OT) mark regions of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Keke Tang , Ziyong Du , Xiaofei Wang , Weilong Peng , Peican Zhu , Zhihong Tian

This paper studies how well generative adversarial networks (GANs) learn probability distributions from finite samples. Our main results establish the convergence rates of GANs under a collection of integral probability metrics defined…

Machine Learning · Computer Science 2022-06-10 Jian Huang , Yuling Jiao , Zhen Li , Shiao Liu , Yang Wang , Yunfei Yang

Current techniques for Out-of-Distribution (OoD) detection predominantly rely on quantifying predictive uncertainty and incorporating model regularization during the training phase, using either real or synthetic OoD samples. However,…

Machine Learning · Computer Science 2023-10-13 Xiaoyang Song , Wenbo Sun , Maher Nouiehed , Raed Al Kontar , Judy Jin

Surface-based geodesic topology provides strong cues for object semantic analysis and geometric modeling. However, such connectivity information is lost in point clouds. Thus we introduce GeoNet, the first deep learning architecture trained…

Computer Vision and Pattern Recognition · Computer Science 2019-01-04 Tong He , Haibin Huang , Li Yi , Yuqian Zhou , Chihao Wu , Jue Wang , Stefano Soatto