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Related papers: Biological connectomes as a representation for the…

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This research report introduces ElegansNet, a neural network that mimics real-world neuronal network circuitry, with the goal of better understanding the interplay between connectome topology and deep learning systems. The proposed approach…

Neural and Evolutionary Computing · Computer Science 2024-04-01 Francesco Bardozzo , Andrea Terlizzi , Pietro Liò , Roberto Tagliaferri

Artificial neural networks for motor control usually adopt generic architectures like fully connected MLPs. While general, these tabula rasa architectures rely on large amounts of experience to learn, are not easily transferable to new…

Machine Learning · Computer Science 2022-11-29 Nikhil X. Bhattasali , Anthony M. Zador , Tatiana A. Engel

Biological neural networks are shaped both by evolution across generations and by individual learning within an organism's lifetime, whereas standard artificial neural networks undergo a single, large training procedure without inherited…

Machine Learning · Computer Science 2025-05-01 Klemen Kotar , Greta Tuckute

Understanding the dynamical behavior of complex systems from their underlying network architectures is a long-standing question in complexity theory. Therefore, many metrics have been devised to extract network features like motifs,…

Neurons and Cognition · Quantitative Biology 2024-09-05 Bryant Avila , Pedro Augusto , David Phillips , Tommaso Gili , Manuel Zimmer , Hernán A. Makse

Given the inner complexity of the human nervous system, insight into the dynamics of brain activity can be gained from understanding smaller and simpler organisms, such as the nematode C. Elegans. The behavioural and structural biology of…

Neurons and Cognition · Quantitative Biology 2021-07-15 Gonçalo Mestre , Ruxandra Barbulescu , Arlindo L. Oliveira , L. Miguel Silveira

We aimed to explore the capability of deep learning to approximate the function instantiated by biological neural circuits-the functional connectome. Using deep neural networks, we performed supervised learning with firing rate observations…

Neurons and Cognition · Quantitative Biology 2022-11-24 Sihao Liu , Augustine N Mavor-Parker , Caswell Barry

C. elegans locomotion is composed of switches between forward and reversal states punctuated by turns. This locomotory capability is necessary for the nematode to move towards attractive stimuli, escape noxious chemicals, and explore its…

Neurons and Cognition · Quantitative Biology 2025-01-03 Megan Morrison , Lai-Sang Young

The connectome, or the entire connectivity of a neural system represented by network, ranges various scales from synaptic connections between individual neurons to fibre tract connections between brain regions. Although the modularity they…

Neurons and Cognition · Quantitative Biology 2014-10-01 Jinseop S. Kim , Marcus Kaiser

The connectome describes the complete set of synaptic contacts through which neurons communicate. While the architecture of the $\textit{C. elegans}$ connectome has been extensively characterized, much less is known about the organization…

Neurons and Cognition · Quantitative Biology 2025-09-18 Sophie Dvali , Caio Seguin , Richard Betzel , Andrew M. Leifer

Several abilities of biological systems, such as adaptation to natural environment, or of animals to learn patterns when appropriately trained, are features that are extremely useful, if emulated by electronic circuits, in applications…

Neurons and Cognition · Quantitative Biology 2011-12-22 M. Di Ventra , Y. V. Pershin

We investigate how locomotory behavior is generated in the brain focusing on the paradigmatic connectome of nematode Caenorhabditis elegans (C. elegans) and on neuronal activity patterns that control forward locomotion. We map the neuronal…

Adaptation and Self-Organizing Systems · Physics 2020-06-17 Thomas Maertens , Eckehard Schöll , Jorge Ruiz , Philipp Hövel

Artificial and natural neural network models are a new toolkit which could be potentially have been used for clarifying of complex brain functions. To attend this goal, such models need to be neurobiologically realistic. However, although…

Neurons and Cognition · Quantitative Biology 2022-07-08 Arsenii Onuchin

While Artificial Neural Networks (ANNs) have yielded impressive results in the realm of simulated intelligent behavior, it is important to remember that they are but sparse approximations of Biological Neural Networks (BNNs). We go beyond…

Neural and Evolutionary Computing · Computer Science 2021-03-30 Krishna Katyal , Jesse Parent , Bradly Alicea

The brain's intricate connectome, a blueprint for its function, presents immense complexity, yet it arises from a compact genetic code, hinting at underlying low-dimensional organizational principles. This work bridges connectomics and…

Artificial Intelligence · Computer Science 2025-05-28 Yubin Li , Xingyu Liu , Guozhang Chen

The complete connectome of the Drosophila larva brain offers a unique opportunity to investigate whether biologically evolved circuits can support artificial intelligence. We convert this wiring diagram into a Biological Processing Unit…

Neural and Evolutionary Computing · Computer Science 2025-07-16 Siyu Yu , Zihan Qin , Tingshan Liu , Beiya Xu , R. Jacob Vogelstein , Jason Brown , Joshua T. Vogelstein

The human brain is a complex system, and understanding its mechanisms has been a long-standing challenge in neuroscience. The study of the functional connectome, which maps the functional connections between different brain regions, has…

Neural and Evolutionary Computing · Computer Science 2025-04-14 Tananun Songdechakraiwut , Yutong Wu

Neuroscience has long informed the development of artificial neural networks, but the success of modern architectures invites, in turn, the converse: can modern networks teach us lessons about brain function? Here, we examine the structure…

Neurons and Cognition · Quantitative Biology 2026-03-17 Peter Koenig , Mario Negrello

We analyse the neural dynamics and its relation with the emergent behaviour of a robotic vehicle that is controlled by a neural network numerical simulation based on the nervous system of the nematode Caenorhabditis elegans. The robot…

Neurons and Cognition · Quantitative Biology 2020-11-19 Carlos E. Valencia Urbina , Sergio A. Cannas , Pablo M. Gleiser

Brain research has been driven by enquiry for principles of brain structure organization and its control mechanisms. The neuronal wiring map of C. elegans, the only complete connectome available till date, presents an incredible opportunity…

Neurons and Cognition · Quantitative Biology 2016-11-28 Rahul Badhwar , Ganesh Bagler

We propose a data-driven approach to represent neuronal network dynamics as a Probabilistic Graphical Model (PGM). Our approach learns the PGM structure by employing dimension reduction to network response dynamics evoked by stimuli applied…

Neurons and Cognition · Quantitative Biology 2017-11-02 Hexuan Liu , Jimin Kim , Eli Shlizerman
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