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Additive manufacturing has revolutionized the building of materials direct from design, allowing high resolution rapid prototyping in complex 3D designs with many materials. 3D printing hasenabled high strength damage-tolerant structures,…
The nucleation and/or spreading of bubbles in water under tension (due to water evaporation) can be problematic for most plants along the ascending sap network from root to leaves, named xylem. Due to global warming, trees facing drought…
Wrinkling of an inextensible elastic lining of an inner-lined tube under imposed pressure is considered. A simple equation modeling the elastic properties of the lining, the pressure, and the soft-substrate forces is derived. This equation…
Gaining access to the cell interior is fundamental for many applications, such as electrical recording, drug and biomolecular delivery. A very promising technique consists of culturing cells on nano/micro pillars. The tight adhesion and…
When a drop of fluid hits a small solid target of comparable size, it expands radially until reaching a maximum diameter and subsequently recedes. In this work, we show that the expansion process of liquid sheets is controlled by a…
Oscillatory shear tests are widely used in rheology to characterize the linear and non-linear mechanical response of complex fluids, including the yielding transition. There is an increasing urge to acquire detailed knowledge of the…
Non-motile elongated bacteria confined in two-dimensional open micro-channels can exhibit collective motion and form dense monolayers with nematic order if the cells proliferate, i.e., grow and divide. Using soft molecular dynamics…
Cellulose nanocrystals (CNC) can be considered as model colloidal rods and have practical applications in the formation of soft materials with tailored anisotropy. Here, we employ two contrasting microfluidic devices to quantitatively…
, Ischial pressure ulcer is an important risk for every paraplegic person and a major public health issue. Pressure ulcers appear following excessive compression of buttock's soft tissues by bony structures, and particularly in ischial and…
Fused Filament Fabrication is an additive manufacturing technique in which molten thermoplastic polymers are extruded through a nozzle. Therefore, the interplay between the viscoelastic nature of the polymer melt, temperature, printing…
Contraction assay based on surface measurement have been widely used to evaluate cell contractility in 3D models. This method is straightforward and requires no specific equipment, but it does not provide quantitative data about contraction…
Animal cells are active, contractile objects. While bioassays address the molecular characterization of cell contractility, the mechanical characterization of the active forces in cells remains challenging. Here by confronting theoretical…
The rheological properties of biological tissues, though fundamental to many physiological and pathological processes such as embryonic development, wound healing, and tumor progression, remain poorly understood. A recent study showed that…
Accurate simulation of deformation processes at the atomic scale is critical for predicting the mechanical response of materials and particularly the calculation of directional flow stresses. This work presents a method for applying…
The mechanical behaviour and symmetry-breaking shape deformation of red blood cells subjected to shear flows is used to demonstrate that far from being random fluids, both the membrane and cytoplasm of every biological cell undergo…
Living cells respond to mechanical changes in the matrix surrounding them by applying contractile forces that are in turn transmitted to distant cells. We calculate the mechanical work that each cell performs in order to deform the matrix,…
A severe application of stress on articular cartilage can initiate a cascade of biochemical reactions that can lead to the development of osteoarthritis. We constructed a multiscale mathematical model of the process with three components:…
Blood viscosity decreases with shear stress, a property essential for an efficient perfusion of the vascular tree. Shear-thinning is intimately related to the dynamics and mutual interactions of red blood cells (RBCs), the major…
The effect of AC electric fields on the elasticity of supported lipid bilayers has been investigated at the microscopic level using grazing incidence synchrotron x-ray scattering. A strong decrease in the membrane tension up to 1mN/m and a…
Comparison of a few simple models of fluid and solid membranes illustrates how shear stresses can arise from a bending energy through a coupling between curvature and surface stresses, a feature incidental to the fluid or solid nature of…