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The RNA inverse folding problem aims to identify nucleotide sequences that preferentially adopt a given target secondary structure. While various heuristic and machine learning-based approaches have been proposed, many require a large…

Machine Learning · Computer Science 2026-02-19 Shuta Kikuchi , Shu Tanaka

Due to the importance of uncertainty quantification (UQ), Bayesian approach to inverse problems has recently gained popularity in applied mathematics, physics, and engineering. However, traditional Bayesian inference methods based on Markov…

Computation · Statistics 2022-04-26 Shiwei Lan , Shuyi Li , Babak Shahbaba

We consider optimal experimental design (OED) for Bayesian nonlinear inverse problems governed by partial differential equations (PDEs) under model uncertainty. Specifically, we consider inverse problems in which, in addition to the…

Numerical Analysis · Mathematics 2024-07-03 Alen Alexanderian , Ruanui Nicholson , Noemi Petra

One of the main challenges for arbitrary-shaped text detection is to design a good text instance representation that allows networks to learn diverse text geometry variances. Most of existing methods model text instances in image spatial…

Computer Vision and Pattern Recognition · Computer Science 2021-04-23 Yiqin Zhu , Jianyong Chen , Lingyu Liang , Zhanghui Kuang , Lianwen Jin , Wayne Zhang

Diffeomorphic image registration (DIR) is a fundamental task in 3D medical image analysis that seeks topology-preserving deformations between image pairs. To ensure diffeomorphism, a common approach is to model the deformation field as the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Mohammadjavad Matinkia , Nilanjan Ray

Data encoding is a common and central operation in most data analysis tasks. The performance of other models downstream in the computational process highly depends on the quality of data encoding. One of the most powerful ways to encode…

Machine Learning · Computer Science 2025-09-03 Teddy Lazebnik , Liron Simon-Keren

Experimental design is central to science and engineering. A ubiquitous challenge is how to maximize the value of information obtained from expensive or constrained experimental settings. Bayesian optimal experimental design (OED) provides…

Methodology · Statistics 2026-02-13 Sofia Mäkinen , Andrew B. Duncan , Tapio Helin

This work investigates in detail the performance and advantages of a new quantum Monte Carlo integrator, dubbed Quantum Fourier Iterative Amplitude Estimation (QFIAE), to numerically evaluate for the first time loop Feynman integrals in a…

High Energy Physics - Phenomenology · Physics 2024-11-20 Jorge J. Martínez de Lejarza , Leandro Cieri , Michele Grossi , Sofia Vallecorsa , Germán Rodrigo

We introduce the novel class $(E_\alpha)_{\alpha \in [-\infty,1)}$ of reverse map projection embeddings, each one defining a unique new method of encoding classical data into quantum states. Inspired by well-known map projections from the…

Quantum Physics · Physics 2024-08-20 Max Arnott , Dimitri Papaioannou , Kieran McDowall , Phalgun Lolur , Bambordé Baldé

Continuous-depth neural networks, such as Neural ODEs, have refashioned the understanding of residual neural networks in terms of non-linear vector-valued optimal control problems. The common solution is to use the adjoint sensitivity…

Machine Learning · Computer Science 2022-02-16 Andrew Corbett , Dmitry Kangin

The interior resonance problem of time domain integral equations (TDIEs) formulated to analyze acoustic field interactions on penetrable objects is investigated. Two types of TDIEs are considered: The first equation, which is termed the…

Computational Physics · Physics 2024-05-22 Rui Chen , Yifei Shi , Sadeed Bin Sayed , Mingyu Lu , Hakan Bagci

This study proposes median consensus embedding (MCE) to address variability in low-dimensional embeddings caused by random initialization in nonlinear dimensionality reduction techniques such as $t$-distributed stochastic neighbor…

Machine Learning · Statistics 2025-12-10 Yui Tomo , Daisuke Yoneoka

A memetic framework for optimal inverse design is proposed by combining a local gradient-based procedure and a robust global scheme. The procedure is based on method-of-moments matrices and does not demand full inversion of a system matrix.…

Optimization and Control · Mathematics 2023-10-10 Miloslav Capek , Lukas Jelinek , Petr Kadlec , Mats Gustafsson

We present a reduced-order model (ROM) methodology for inverse scattering problems in which the reduced-order models are data-driven, i.e. they are constructed directly from data gathered by sensors. Moreover, the entries of the ROM contain…

Numerical Analysis · Mathematics 2023-06-16 Jörn Zimmerling , Vladimir Druskin , Murthy Guddati , Elena Cherkaev , Rob Remis

Machine learning applied to computer vision and signal processing is achieving results comparable to the human brain on specific tasks due to the great improvements brought by the deep neural networks (DNN). The majority of state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2020-06-30 José Augusto Stuchi , Levy Boccato , Romis Attux

Embedding static graphs in low-dimensional vector spaces plays a key role in network analytics and inference, supporting applications like node classification, link prediction, and graph visualization. However, many real-world networks…

Machine Learning · Computer Science 2021-07-23 Claudio D. T. Barros , Matheus R. F. Mendonça , Alex B. Vieira , Artur Ziviani

We present a new fixed mesh algorithm for solving a class of interface inverse problems for the typical elliptic interface problems. These interface inverse problems are formulated as shape optimization prob- lems whose objective…

Numerical Analysis · Mathematics 2018-10-18 Ruchi Guo , Tao Lin , Yanping Lin

Inverse problems in partial differential equations (PDEs) involve estimating the physical parameters of a system from observed spatiotemporal solution fields. Neural networks are well-suited for PDE parameter estimation due to their…

Machine Learning · Computer Science 2026-05-27 Divyam Goel , Nithin Chalapathi , Sanjeev Raja , Aditi S. Krishnapriyan

The field of quantum computing has experienced a rapid expansion in recent years, with ongoing exploration of new technologies, a decrease in error rates, and a growth in the number of qubits available in quantum processors. However,…

Quantum Physics · Physics 2023-03-16 Samuel Stein , Nathan Wiebe , Yufei Ding , James Ang , Ang Li

Graph embedding has become a key component of many data mining and analysis systems. Current graph embedding approaches either sample a large number of node pairs from a graph to learn node embeddings via stochastic optimization or…

Social and Information Networks · Computer Science 2019-12-20 Artem Lutov , Dingqi Yang , Philippe Cudré-Mauroux