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Medical Image Segmentation is a useful application for medical image analysis including detecting diseases and abnormalities in imaging modalities such as MRI, CT etc. Deep learning has proven to be promising for this task but usually has a…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Soham Bhosale , Arjun Krishna , Ge Wang , Klaus Mueller

Medical image segmentation is critical for disease diagnosis and treatment assessment. However, concerns regarding the reliability of segmentation regions persist among clinicians, mainly attributed to the absence of confidence assessment,…

Image and Video Processing · Electrical Eng. & Systems 2025-09-12 Ke Zou , Yidi Chen , Ling Huang , Xuedong Yuan , Xiaojing Shen , Meng Wang , Rick Siow Mong Goh , Yong Liu , Huazhu Fu

Fully convolutional neural networks (FCNs), and in particular U-Nets, have achieved state-of-the-art results in semantic segmentation for numerous medical imaging applications. Moreover, batch normalization and Dice loss have been used…

Image and Video Processing · Electrical Eng. & Systems 2020-07-06 Alireza Mehrtash , William M. Wells , Clare M. Tempany , Purang Abolmaesumi , Tina Kapur

Medical experts often manually segment images to obtain diagnostic statistics and discard the resulting annotations. We aim to train segmentation models to alleviate this burden, but constrained to the retained summary statistics (e.g., the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Omkar Kulkarni , Edward Raff , Tim Oates

Transfer learning leverages pre-trained model features from a large dataset to save time and resources when training new models for various tasks, potentially enhancing performance. Due to the lack of large datasets in the medical imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-11-10 Gabriel Efrain Humpire-Mamani , Colin Jacobs , Mathias Prokop , Bram van Ginneken , Nikolas Lessmann

When applying a Deep Learning model to medical images, it is crucial to estimate the model uncertainty. Voxel-wise uncertainty is a useful visual marker for human experts and could be used to improve the model's voxel-wise output, such as…

Image and Video Processing · Electrical Eng. & Systems 2022-11-02 Anton Vasiliuk , Daria Frolova , Mikhail Belyaev , Boris Shirokikh

The field of medical image segmentation is hindered by the scarcity of large, publicly available annotated datasets. Not all datasets are made public for privacy reasons, and creating annotations for a large dataset is time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Iira Häkkinen , Iaroslav Melekhov , Erik Englesson , Hossein Azizpour , Juho Kannala

Imperfect labels limit the quality of predictions learned by deep neural networks. This is particularly relevant in medical image segmentation, where reference annotations are difficult to collect and vary significantly even across expert…

Computer Vision and Pattern Recognition · Computer Science 2021-07-07 Eugene Vorontsov , Samuel Kadoury

Semi-supervised learning relaxes the need of large pixel-wise labeled datasets for image segmentation by leveraging unlabeled data. A prominent way to exploit unlabeled data is to regularize model predictions. Since the predictions of…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Sukesh Adiga , Jose Dolz , Herve Lombaert

The necessity of large amounts of labeled data to train deep models, especially in medical imaging creates an implementation bottleneck in resource-constrained settings. In Insite (labelINg medical imageS usIng submodular funcTions and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Akshat Gautam , Anurag Shandilya , Akshit Srivastava , Venkatapathy Subramanian , Ganesh Ramakrishnan , Kshitij Jadhav

In microscopy image cell segmentation, it is common to train a deep neural network on source data, containing different types of microscopy images, and then fine-tune it using a support set comprising a few randomly selected and annotated…

Computer Vision and Pattern Recognition · Computer Science 2022-11-21 Youssef Dawoud , Arij Bouazizi , Katharina Ernst , Gustavo Carneiro , Vasileios Belagiannis

Clinical researchers often select among and evaluate risk prediction models using standard machine learning metrics based on confusion matrices. However, if these models are used to allocate interventions to patients, standard metrics…

Machine Learning · Statistics 2020-06-03 Alejandro Schuler , Aashish Bhardwaj , Vincent Liu

Performance measures are an important tool for assessing and comparing different medical image segmentation algorithms. Unfortunately, the current measures have their weaknesses when it comes to assessing certain edge cases. These…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Dennis Hartmann , Verena Schmid , Philip Meyer , Iñaki Soto-Rey , Dominik Müller , Frank Kramer

High-quality pixel-level annotations of medical images are essential for supervised segmentation tasks, but obtaining such annotations is costly and requires medical expertise. To address this challenge, we propose a novel coarse-to-fine…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Anghong Du , Nay Aung , Theodoros N. Arvanitis , Stefan K. Piechnik , Joao A C Lima , Steffen E. Petersen , Le Zhang

In medical image segmentation, uncertainty estimates are often reported but rarely used to guide decisions. We study the missing step: how uncertainty maps are converted into actionable policies such as accepting, flagging, or deferring…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Saket Maganti

Accurate annotation of medical image is the crucial step for image AI clinical application. However, annotating medical image will incur a great deal of annotation effort and expense due to its high complexity and needing experienced…

Machine Learning · Computer Science 2019-01-09 Yang Deng , Yao Sun , Yongpei Zhu , Yue Xu , Qianxi Yang , Shuo Zhang , Mingwang Zhu , Jirang Sun , Weiling Zhao , Xiaobo Zhou , Kehong Yuan

Manual segmentation is used as the gold-standard for evaluating neural networks on automated image segmentation tasks. Due to considerable heterogeneity in shapes, colours and textures, demarcating object boundaries is particularly…

Image and Video Processing · Electrical Eng. & Systems 2021-11-02 Michael Yeung , Guang Yang , Evis Sala , Carola-Bibiane Schönlieb , Leonardo Rundo

Purpose: An investigation of the challenge of annotating discrete segmentations of brain tumours in ultrasound, with a focus on the issue of aleatoric uncertainty along the tumour margin, particularly for diffuse tumours. A segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Alistair Weld , Luke Dixon , Alfie Roddan , Giulio Anichini , Sophie Camp , Stamatia Giannarou

Deep learning methods have been shown to be effective for the automatic segmentation of structures and pathologies in medical imaging. However, they require large annotated datasets, whose manual segmentation is a tedious and time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2022-09-27 Bella Specktor Fadida , Daphna Link Sourani , Liat Ben Sira Elka Miller , Dafna Ben Bashat , Leo Joskowicz

Image segmentation is a fundamental problem in biomedical image analysis. Recent advances in deep learning have achieved promising results on many biomedical image segmentation benchmarks. However, due to large variations in biomedical…

Computer Vision and Pattern Recognition · Computer Science 2017-06-16 Lin Yang , Yizhe Zhang , Jianxu Chen , Siyuan Zhang , Danny Z. Chen