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Two losing games, when alternated in a periodic or random fashion, can produce a winning game. This paradox occurs in a family of stochastic processes: if one combines two or more dynamics where a given quantity decreases, the result can be…

Statistical Mechanics · Physics 2007-05-23 J. M. R. Parrondo , B. J. de Cisneros

A prerequisite for isolating diseased cells requires a mechanism for effective mass-based separation. This objective, however, is generally rather challenging because typically no valid correlation exists between the size of the particles…

Statistical Mechanics · Physics 2019-03-27 Aleksandra Słapik , Jerzy Łuczka , Peter Hänggi , Jakub Spiechowicz

We introduce an alternative route for obtaining reliable cyclic engines, based on interacting Brownian particles under time-periodic drivings. General expressions for the thermodynamic fluxes, such as power and heat, are obtained using the…

Statistical Mechanics · Physics 2022-02-16 Iago N. Mamede , Pedro E. Harunari , Bruno A. N. Akasaki , Karel Proesmans , Carlos E. Fiore

Molecular motors are essential to the living, they generate additional fluctuations that boost transport and assist assembly. Self-propelled colloids, that consume energy to move, hold similar potential for the man-made assembly of…

Soft Condensed Matter · Physics 2019-09-18 Sophie Ramananarivo , Etienne Ducrot , Jeremie Palacci

Uncertainties are abundant in complex systems. Mathematical models for these systems thus contain random effects or noises. The models are often in the form of stochastic differential equations, with some parameters to be determined by…

Numerical Analysis · Mathematics 2015-03-13 Jiarui Yang , Jinqiao Duan

In living cells, molecular motors convert chemical energy into mechanical work. Its thermodynamic energy efficiency, i.e. the ratio of output mechanical work to input chemical energy, is usually high. However, using two-state models, we…

Biological Physics · Physics 2015-03-06 Yunxin Zhang

Transport properties of a hard-sphere colloidal fluid are investigated by Brownian dynamics simulations. We implement a novel algorithm for the time-dependent velocity-autocorrelation function (VACF) essentially eliminating the noise of the…

Soft Condensed Matter · Physics 2020-04-23 Suvendu Mandal , Lukas Schrack , Hartmut Löwen , Matthias Sperl , Thomas Franosch

Manipulating and coupling molecule gears is the first step towards realizing molecular-scale mechanical machines. Here, we theoretically investigate the behavior of such gears using molecular dynamics simulations. Within a nearly rigid-body…

Soft Condensed Matter · Physics 2020-03-12 H. -H. Lin , A. Croy , R. Gutierrez , C. Joachim , G. Cuniberti

Microtubules and motor proteins self organize into biologically important assemblies including the mitotic spindle and the centrosomal microtubule array. Outside of cells, microtubule-motor mixtures can form novel active liquid-crystalline…

Soft Condensed Matter · Physics 2016-01-20 Tong Gao , Robert Blackwell , Matthew A. Glaser , M. D. Betterton , Michael J. Shelley

Molecular motors are found throughout the cells of the human body, and have many different and important roles. These micro-machines move along filament tracks, and have the ability to convert chemical energy into mechanical work that…

Biological Physics · Physics 2015-06-03 Nadiv Dharan , Oded Farago

We derive the distribution of particle currents for a system of interacting active Brownian particles in the long time limit using large deviation theory and a weighted many body expansion. We find the distribution is non-Gaussian, except…

Statistical Mechanics · Physics 2018-12-19 Trevor GrandPre , David T. Limmer

Using molecular dynamics simulations, we study particle-transport in a system of interacting colloidal particles on a ring, where the system is driven by a time-dependent external potential, moving along the ring. We consider two driving…

Statistical Mechanics · Physics 2018-12-06 Shubhashis Rana , Sanchari Goswami , Sakuntala Chatterjee , Punyabrata Pradhan

The purpose of this work is to present the concept of an autonomous Stirling-like engine powered by anisotropy of thermodynamic fluctuations. Specifically, simultaneous contact of a thermodynamic system with two heat baths along coupled…

Statistical Mechanics · Physics 2022-03-24 Olga Movilla Miangolarra , Amirhossein Taghvaei , Yongxin Chen , Tryphon T. Georgiou

Intracellular transport is mediated by molecular motors that pull cargos along cytoskeletal filaments. Many cargos move bidirectionally and are transported by two teams of motors which move into opposite directions along the filament. We…

Biological Physics · Physics 2008-12-16 Melanie J. I. Muller , Stefan Klumpp , Reinhard Lipowsky

Deep learning has enjoyed much recent success, and applying state-of-the-art model learning methods to controls is an exciting prospect. However, there is a strong reluctance to use these methods on safety-critical systems, which have…

Systems and Control · Electrical Eng. & Systems 2021-07-06 David D. Fan , Jennifer Nguyen , Rohan Thakker , Nikhilesh Alatur , Ali-akbar Agha-mohammadi , Evangelos A. Theodorou

While molecular machines play an increasingly significant role in nanoscience research and applications, there remains a shortage of investigations and understanding of the molecular gear (cogwheel), which is an indispensable and…

Chemical Physics · Physics 2018-02-07 Rundong Zhao , Yan-Ling Zhao , Fei Qi , Klaus Hermann , Rui-Qin Zhang , Michel A. Van Hove

Driving a quantum system periodically in time can profoundly alter its long-time dynamics and trigger topological order. Such schemes are particularly promising for generating non-trivial energy bands and gauge structures in quantum-matter…

Quantum Gases · Physics 2015-06-11 N. Goldman , J. Dalibard

Anomalously slow passive diffusion, $\langle \delta x^2(t)\rangle\simeq t^{\alpha}$, with $0<\alpha<1$, of larger tracers such as messenger RNA and endogenous submicron granules in the cytoplasm of living biological cells has been…

Biological Physics · Physics 2014-09-24 Igor Goychuk , Vasyl O. Kharchenko , Ralf Metzler

The problem of Brownian motion in a periodic potential, under the influence of external forcing, which is either random or periodic in time, is studied in this paper. Multiscale techniques are used to derive general formulae for the steady…

Statistical Mechanics · Physics 2007-05-23 G. A. Pavliotis

This work deals with the overdamped motion of a particle in a fluctuating one-dimensional periodic potential. If the potential has no inversion symmetry and its fluctuations are asymmetric and correlated in time, a net flow can be generated…

Condensed Matter · Physics 2016-10-26 Enrique Abad , Andreas Mielke