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The brain effortlessly extracts latent causes of stimuli, but how it does this at the network level remains unknown. Most prior attempts at this problem proposed neural networks that implement independent component analysis which works…

Signal Processing · Electrical Eng. & Systems 2023-04-11 Bariscan Bozkurt , Ates Isfendiyaroglu , Cengiz Pehlevan , Alper T. Erdogan

Blind source separation, i.e. extraction of independent sources from a mixture, is an important problem for both artificial and natural signal processing. Here, we address a special case of this problem when sources (but not the mixing…

Neurons and Cognition · Quantitative Biology 2017-10-20 Cengiz Pehlevan , Sreyas Mohan , Dmitri B. Chklovskii

An important problem encountered by both natural and engineered signal processing systems is blind source separation. In many instances of the problem, the sources are bounded by their nature and known to be so, even though the particular…

Signal Processing · Electrical Eng. & Systems 2020-04-14 Alper T. Erdogan , Cengiz Pehlevan

Blind source separation (BSS) is a natural framework for studying how latent causes may be recovered from sensory mixtures, but deriving online and biologically plausible algorithms for structured (i.e., constrained to known domains) and…

Machine Learning · Computer Science 2026-05-22 Bariscan Bozkurt , Efe Ali Gorguner , Francesco Innocenti , Rafal Bogacz

An important problem in neuroscience is to understand how brains extract relevant signals from mixtures of unknown sources, i.e., perform blind source separation. To model how the brain performs this task, we seek a biologically plausible…

Signal Processing · Electrical Eng. & Systems 2022-03-08 David Lipshutz , Cengiz Pehlevan , Dmitri B. Chklovskii

Blind source separation (BSS) algorithms are unsupervised methods, which are the cornerstone of hyperspectral data analysis by allowing for physically meaningful data decompositions. BSS problems being ill-posed, the resolution requires…

Signal Processing · Electrical Eng. & Systems 2022-09-28 Rémi Carloni Gertosio , Jérôme Bobin , Fabio Acero

In this work, we consider the problem of blind source separation (BSS) by departing from the usual linear model and focusing on the linear-quadratic (LQ) model. We propose two provably robust and computationally tractable algorithms to…

Signal Processing · Electrical Eng. & Systems 2021-12-20 Christophe Kervazo , Nicolas Gillis , Nicolas Dobigeon

The backpropagation algorithm has experienced remarkable success in training large-scale artificial neural networks; however, its biological plausibility has been strongly criticized, and it remains an open question whether the brain…

Neural and Evolutionary Computing · Computer Science 2026-03-27 Bariscan Bozkurt , Cengiz Pehlevan , Alper T Erdogan

Humans excel at continually acquiring, consolidating, and retaining information from an ever-changing environment, whereas artificial neural networks (ANNs) exhibit catastrophic forgetting. There are considerable differences in the…

Neural and Evolutionary Computing · Computer Science 2023-04-17 Fahad Sarfraz , Elahe Arani , Bahram Zonooz

The backpropagation (BP) algorithm is often thought to be biologically implausible in the brain. One of the main reasons is that BP requires symmetric weight matrices in the feedforward and feedback pathways. To address this "weight…

Machine Learning · Computer Science 2018-12-24 Will Xiao , Honglin Chen , Qianli Liao , Tomaso Poggio

Blind source separation (BSS) aims to recover an unobserved signal $S$ from its mixture $X=f(S)$ under the condition that the effecting transformation $f$ is invertible but unknown. As this is a basic problem with many practical…

Statistics Theory · Mathematics 2023-03-20 Alexander Schell

We consider the problem of adaptive blind separation of two sources from their instantaneous mixtures. We focus on the case where the two sources are not necessarily independent. By analyzing a general form of adaptive algorithms we show…

Signal Processing · Electrical Eng. & Systems 2019-08-08 George V. Moustakides , Feeby Salib , Kalliopi Basioti

Developing biologically plausible learning algorithms that can achieve performance comparable to error backpropagation remains a longstanding challenge. Existing approaches often compromise biological plausibility by entirely avoiding the…

Neural and Evolutionary Computing · Computer Science 2026-02-12 Changze Lv , Yifei Wang , Yanxun Zhang , Yiyang Lu , Jingwen Xu , Xiaohua Wang , Di Yu , Xin Du , Xuanjing Huang , Xiaoqing Zheng

We introduce a new information maximization (infomax) approach for the blind source separation problem. The proposed framework provides an information-theoretic perspective for determinant maximization-based structured matrix factorization…

Information Theory · Computer Science 2022-05-03 Alper T. Erdogan

Backpropagation is a cornerstone algorithm in training neural networks for supervised learning, which uses a gradient descent method to update network weights by minimizing the discrepancy between actual and desired outputs. Despite its…

An important preprocessing step in most data analysis pipelines aims to extract a small set of sources that explain most of the data. Currently used algorithms for blind source separation (BSS), however, often fail to extract the desired…

Machine Learning · Statistics 2018-03-26 Alexander Böttcher , Wieland Brendel , Bernhard Englitz , Matthias Bethge

Our brain consists of biological neurons encoding information through accurate spike timing, yet both the architecture and learning rules of our brain remain largely unknown. Comparing to the recent development of backpropagation-based…

Neural and Evolutionary Computing · Computer Science 2021-11-29 Yukun Yang , Peng Li

Significant challenges exist in efficient data analysis of most advanced experimental and observational techniques because the collected signals often include unwanted contributions--such as background and signal distortions--that can…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Yuan Ni , Zhantao Chen , Alexander N. Petsch , Edmund Xu , Cheng Peng , Alexander I. Kolesnikov , Sugata Chowdhury , Arun Bansil , Jana B. Thayer , Joshua J. Turner

Background and Objective: Processing electrophysiological signals often requires blind source separation (BSS) due to the nature of mixing source signals. However, its complex computational demands make real-time BSS challenging. The…

Human-Computer Interaction · Computer Science 2024-11-28 Yao Li , Haowen Zhao , Yunfei Liu , Xu Zhang

We give under weak assumptions a complete combinatorial characterization of identifiability for linear mixtures of finite alphabet sources, with unknown mixing weights and unknown source signals, but known alphabet. This is based on a…

Methodology · Statistics 2017-09-01 Merle Behr , Axel Munk
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