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To develop a new method to quantify nonperfused retinal capillaries (NPCs) by using co-registered optical coherence tomography (OCT) and OCT angiography (OCTA), and to evaluate NPCs in eyes with age-related macular degeneration (AMD) and…

Quantitative Methods · Quantitative Biology 2024-11-11 Min Gao , Yukun Guo , Tristan T. Hormel , Jie Wang , Elizabeth White , Dong-Wouk Park , Thomas S. Hwang , Steven T. Bailey , Yali Jia

In medical imaging, there are clinically relevant segmentation tasks where the output mask is a projection to a subset of input image dimensions. In this work, we propose a novel convolutional neural network architecture that can…

Image and Video Processing · Electrical Eng. & Systems 2021-08-03 Dmitrii Lachinov , Philipp Seeboeck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunovic

Optical coherence tomography (OCT) is a non-invasive, high-resolution imaging technology that provides cross-sectional images of tissues. Dense acquisition of A-scans along the fast axis is required to obtain high digital resolution images.…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Zezhao Guo , Zhanfang Zhao

Advancements in medical imaging and endovascular grafting have facilitated minimally invasive treatments for aortic diseases. Accurate 3D segmentation of the aorta and its branches is crucial for interventions, as inaccurate segmentation…

Optical coherence tomography angiography (OCTA) is a novel noninvasive imaging modality for visualization of retinal blood flow in the human retina. Using specific OCTA imaging biomarkers for the identification of pathologies, automated…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Anna Breger , Felix Goldbach , Bianca S. Gerendas , Ursula Schmidt-Erfurth , Martin Ehler

Glaucoma is one of the leading causes of irreversible blindness. Segmentation of optic disc (OD) and optic cup (OC) on fundus images is a crucial step in glaucoma screening. Although many deep learning models have been constructed for this…

Image and Video Processing · Electrical Eng. & Systems 2023-04-11 Ziyang Chen , Yongsheng Pan , Yong Xia

Diabetic Retinopathy (DR), an ocular complication of diabetes, is a leading cause of blindness worldwide. Traditionally, DR is monitored using Color Fundus Photography (CFP), a widespread 2-D imaging modality. However, DR classifications…

Purpose: Deep learning methods have shown promising results in the segmentation, and detection of diseases in medical images. However, most methods are trained and tested on data from a single source, modality, organ, or disease type,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Nchongmaje Ndipenocha , Alina Mirona , Kezhi Wanga , Yongmin Li

Optical coherence tomography (OCT) is a medical imaging modality that allows us to probe deeper substructures of skin. The state-of-the-art wound care prediction and monitoring methods are based on visual evaluation and focus on surface…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Prashant Kumar , Swatantra Dhara , Ayan Gope , Jyotirmoy Chatterjee , Subhamoy Mandal

From diagnosing neovascular diseases to detecting white matter lesions, accurate tiny vessel segmentation in fundus images is critical. Promising results for accurate vessel segmentation have been known. However, their effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2021-04-20 Suraj Mishra , Danny Z. Chen , X. Sharon Hu

Optical Coherence Tomography is a technique used to scan the Retina of the eye and check for tears. In this paper, we develop a Convolutional Neural Network Architecture for OCT scan classification. The model is trained to detect Retinal…

Computer Vision and Pattern Recognition · Computer Science 2022-12-01 Adit Magotra , Aagat Gedam , Tanush Savadi , Emily Li

Stroke is a major public health problem, affecting millions worldwide. Deep learning has recently demonstrated promise for enhancing the diagnosis and risk prediction of stroke. However, existing methods rely on costly medical imaging…

Image and Video Processing · Electrical Eng. & Systems 2025-12-17 Saeed Shurrab , Aadim Nepal , Terrence J. Lee-St. John , Nicola G. Ghazi , Bartlomiej Piechowski-Jozwiak , Farah E. Shamout

Retinal optical coherence tomography (OCT) images provide crucial insights into the health of the posterior ocular segment. Therefore, the advancement of automated image analysis methods is imperative to equip clinicians and researchers…

Image and Video Processing · Electrical Eng. & Systems 2024-02-16 Jiahao Wang , Hong Peng , Shengchao Chen , Sufen Ren

Optical coherence tomography (OCT) captures cross-sectional data and is used for the screening, monitoring, and treatment planning of retinal diseases. Technological developments to increase the speed of acquisition often results in systems…

Image and Video Processing · Electrical Eng. & Systems 2023-01-03 Timothy T. Yu , Da Ma , Jayden Cole , Myeong Jin Ju , Mirza F. Beg , Marinko V. Sarunic

Retinal image segmentation plays an important role in automatic disease diagnosis. This task is very challenging because the complex structure and texture information are mixed in a retinal image, and distinguishing the information is…

Image and Video Processing · Electrical Eng. & Systems 2020-08-04 Shihao Zhang , Huazhu Fu , Yanwu Xu , Yanxia Liu , Mingkui Tan

AI-based vascular segmentation is becoming increasingly common in enhancing the screening and treatment of ophthalmic diseases. Deep learning structures based on U-Net have achieved relatively good performance in vascular segmentation.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-07 Zhihao Zhao , Yinzheng Zhao , Junjie Yang , Kai Huang , Nassir Navab , M. Ali Nasseri

Existing multi-scale solutions lead to a risk of just increasing the receptive field sizes while neglecting small receptive fields. Thus, it is a challenging problem to effectively construct adaptive neural networks for recognizing various…

Computer Vision and Pattern Recognition · Computer Science 2022-09-22 Qingbei Guo , Xiao-Jun Wu , Zhiquan Feng , Tianyang Xu , Cong Hu

Automatic diabetic retinopathy (DR) lesions segmentation makes great sense of assisting ophthalmologists in diagnosis. Although many researches have been conducted on this task, most prior works paid too much attention to the designs of…

Image and Video Processing · Electrical Eng. & Systems 2022-01-27 Shiqi Huang , Jianan Li , Yuze Xiao , Ning Shen , Tingfa Xu

The Segment Anything Model (SAM) has gained significant attention in the field of image segmentation due to its impressive capabilities and prompt-based interface. While SAM has already been extensively evaluated in various domains, its…

Image and Video Processing · Electrical Eng. & Systems 2023-09-01 Botond Fazekas , José Morano , Dmitrii Lachinov , Guilherme Aresta , Hrvoje Bogunović

Retinal vessel segmentation is a vital step for the diagnosis of many early eye-related diseases. In this work, we propose a new deep learning model, namely Channel Attention Residual U-Net (CAR-UNet), to accurately segment retinal vascular…

Image and Video Processing · Electrical Eng. & Systems 2020-10-22 Changlu Guo , Márton Szemenyei , Yangtao Hu , Wenle Wang , Wei Zhou , Yugen Yi