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Optical coherence tomography (OCT) is a non-invasive imaging technique that can produce images of the eye at the microscopic level. OCT image segmentation to localise retinal layer boundaries is a fundamental procedure for diagnosing and…

Computer Vision and Pattern Recognition · Computer Science 2016-09-09 Jinming Duan , Christopher Tench , Irene Gottlob , Frank Proudlock , Li Bai

The caliber and configuration of retinal blood vessels serve as important biomarkers for various diseases and medical conditions. A thorough analysis of the retinal vasculature requires the segmentation of the blood vessels and their…

Image and Video Processing · Electrical Eng. & Systems 2025-03-13 José Morano , Guilherme Aresta , Hrvoje Bogunović

Optical coherence tomography angiography (OCTA) is a novel non-invasive imaging technique that allows visualizations of vasculature and foveal avascular zone (FAZ) across retinal layers. Clinical researches suggest that the morphology and…

Image and Video Processing · Electrical Eng. & Systems 2021-07-14 Li Lin , Zhonghua Wang , Jiewei Wu , Yijin Huang , Junyan Lyu , Pujin Cheng , Jiong Wu , Xiaoying Tang

The choroid is a key vascular layer of the eye, supplying oxygen to the retinal photoreceptors. Non-invasive enhanced depth imaging optical coherence tomography (EDI-OCT) has recently improved access and visualisation of the choroid, making…

Retinal vessel segmentation is a crucial step in diagnosing and screening various diseases, including diabetes, ophthalmologic diseases, and cardiovascular diseases. In this paper, we propose an effective and efficient method for vessel…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Zhun Fan , Jiajie Mo , Benzhang Qiu , Wenji Li , Guijie Zhu , Chong Li , Jianye Hu , Yibiao Rong , Xinjian Chen

Noisy data and the similarity in the ocular appearances caused by different ophthalmic pathologies pose significant challenges for an automated expert system to accurately detect retinal diseases. In addition, the lack of knowledge…

Image and Video Processing · Electrical Eng. & Systems 2021-10-20 Sharif Amit Kamran , Alireza Tavakkoli , Stewart Lee Zuckerbrod

Optical coherence tomography (OCT) is a non-invasive imaging technique widely used for ophthalmology. It can be extended to OCT angiography (OCT-A), which reveals the retinal vasculature with improved contrast. Recent deep learning…

Image and Video Processing · Electrical Eng. & Systems 2021-07-12 Dewei Hu , Can Cui , Hao Li , Kathleen E. Larson , Yuankai K. Tao , Ipek Oguz

Despite significant advances in artificial intelligence (AI) for computer vision, its application in medical imaging has been limited by the burden and limits of expert-generated labels. We used images from optical coherence tomography…

Computer Vision and Pattern Recognition · Computer Science 2018-02-27 Cecilia S. Lee , Ariel J. Tyring , Yue Wu , Sa Xiao , Ariel S. Rokem , Nicolaas P. Deruyter , Qinqin Zhang , Adnan Tufail , Ruikang K. Wang , Aaron Y. Lee

Optical coherence tomography angiography (OCTA) is a non-invasive imaging technique widely used to study vascular structures and micro-circulation dynamics in the retina and choroid. OCTA has been widely used in clinics for diagnosing…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Kejie Chen , Guanbing Gao , Xiaochun Yang , Wenbo Wang , Jing Na

Age-related macular degeneration (AMD) and choroidal neovascularization (CNV)-related conditions are leading causes of vision loss worldwide, with optical coherence tomography (OCT) serving as a cornerstone for early detection and…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Erfan Nourbakhsh , Nasrin Sanjari , Ali Nourbakhsh

Segmenting of clinically important retinal blood vessels into arteries and veins is a prerequisite for retinal vessel analysis. Such analysis can provide potential insights and bio-markers for identifying and diagnosing various retinal eye…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Sharan SK , Subin Sahayam , Umarani Jayaraman , Lakshmi Priya A

Automated and accurate segmentation of cystoid structures in Optical Coherence Tomography (OCT) is of interest in the early detection of retinal diseases. It is, however, a challenging task. We propose a novel method for localizing cysts in…

Computer Vision and Pattern Recognition · Computer Science 2017-08-29 Karthik Gopinath , Jayanthi Sivaswamy

Optical coherence tomography (OCT) is commonly used to analyze retinal layers for assessment of ocular diseases. In this paper, we propose a method for retinal layer segmentation and quantification of uncertainty based on Bayesian deep…

Computer Vision and Pattern Recognition · Computer Science 2018-09-13 Suman Sedai , Bhavna Antony , Dwarikanath Mahapatra , Rahil Garnavi

Retinal vessel segmentation plays an imaportant role in the field of retinal image analysis because changes in retinal vascular structure can aid in the diagnosis of diseases such as hypertension and diabetes. In recent research, numerous…

Image and Video Processing · Electrical Eng. & Systems 2020-04-09 Changlu Guo , Márton Szemenyei , Yugen Yi , Ying Xue , Wei Zhou , Yangyuan Li

Various deep learning models have been developed to segment anatomical structures from medical images, but they typically have poor performance when tested on another target domain with different data distribution. Recently, unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2022-01-21 Linkai Peng , Li Lin , Pujin Cheng , Ziqi Huang , Xiaoying Tang

Optical coherence tomography angiography (OCTA) has drawn numerous attentions in ophthalmology. However, its data acquisition is time-consuming, because it is based on temporal-decorrelation principle thus requires multiple repeated…

Medical Physics · Physics 2019-10-15 Jianlong Yang , Peng Liu , Lixin Duan , Yan Hu , Jiang Liu

Structural changes in retinal blood vessels are critical biomarkers for the onset and progression of glaucoma and other ocular diseases. However, current vessel segmentation approaches largely rely on supervised learning and extensive…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Cheng Huang , Weizheng Xie , Fan Gao , Yutong Liu , Ruoling Wu , Zeyu Han , Jingxi Qiu , Xiangxiang Wang , Zhenglin Yang , Hao Wang , Yongbin Yu

Precision in identifying and differentiating micro and macro blood vessels in the retina is crucial for the diagnosis of retinal diseases, although it poses a significant challenge. Current autoencoding-based segmentation approaches…

Image and Video Processing · Electrical Eng. & Systems 2024-03-05 Rui Yang , Shunpu Zhang

The utilisation of deep learning segmentation algorithms that learn complex organs and tissue patterns and extract essential regions of interest from the noisy background to improve the visual ability for medical image diagnosis has…

Computer Vision and Pattern Recognition · Computer Science 2023-11-03 Yanming Guo

Accurate retinal vessel segmentation is an important task for many computer-aided diagnosis systems. Yet, it is still a challenging problem due to the complex vessel structures of an eye. Numerous vessel segmentation methods have been…

Image and Video Processing · Electrical Eng. & Systems 2022-03-23 Ali Karaali , Rozenn Dahyot , Donal J. Sexton
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