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Deep learning models have achieved high performance in medical applications, however, their adoption in clinical practice is hindered due to their black-box nature. Self-explainable models, like prototype-based models, can be especially…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Shreyasi Pathak , Jörg Schlötterer , Jeroen Veltman , Jeroen Geerdink , Maurice van Keulen , Christin Seifert

Recent applications of deep convolutional neural networks in medical imaging raise concerns about their interpretability. While most explainable deep learning applications use post hoc methods (such as GradCAM) to generate feature…

Computer Vision and Pattern Recognition · Computer Science 2023-04-17 Yuanyuan Wei , Roger Tam , Xiaoying Tang

Interpretability is a key requirement for the use of machine learning models in high-stakes applications, including medical diagnosis. Explaining black-box models mostly relies on post-hoc methods that do not faithfully reflect the model's…

Artificial Intelligence · Computer Science 2024-06-25 Kerol Djoumessi , Bubacarr Bah , Laura Kühlewein , Philipp Berens , Lisa Koch

In meta-learning approaches, it is difficult for a practitioner to make sense of what kind of representations the model employs. Without this ability, it can be difficult to both understand what the model knows as well as to make meaningful…

Machine Learning · Computer Science 2022-04-05 Pedro Sandoval-Segura , Wallace Lawson

Prototypical-part models are a popular interpretable alternative to black-box deep learning models for computer vision. However, they are difficult to train, with high sensitivity to hyperparameter tuning, inhibiting their application to…

Computer Vision and Pattern Recognition · Computer Science 2024-06-24 Frank Willard , Luke Moffett , Emmanuel Mokel , Jon Donnelly , Stark Guo , Julia Yang , Giyoung Kim , Alina Jade Barnett , Cynthia Rudin

Prototypical part network (ProtoPNet) methods have been designed to achieve interpretable classification by associating predictions with a set of training prototypes, which we refer to as trivial prototypes because they are trained to lie…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Chong Wang , Yuyuan Liu , Yuanhong Chen , Fengbei Liu , Yu Tian , Davis J. McCarthy , Helen Frazer , Gustavo Carneiro

Pretrained transformer-based Language Models (LMs) are well-known for their ability to achieve significant improvement on text classification tasks with their powerful word embeddings, but their black-box nature, which leads to a lack of…

Computation and Language · Computer Science 2024-12-23 Ximing Wen , Wenjuan Tan , Rosina O. Weber

As AI systems grow more capable, it becomes increasingly important that their decisions remain understandable and aligned with human expectations. A key challenge is the limited interpretability of deep models. Post-hoc methods like GradCAM…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Mahdi Alehdaghi , Rajarshi Bhattacharya , Pourya Shamsolmoali , Rafael M. O. Cruz , Maguelonne Heritier , Eric Granger

In the context of image classification, Concept Bottleneck Models (CBMs) first embed images into a set of human-understandable concepts, followed by an intrinsically interpretable classifier that predicts labels based on these intermediate…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Haifei Zhang , Patrick Barry , Eduardo Brandao

We present a deformable prototypical part network (Deformable ProtoPNet), an interpretable image classifier that integrates the power of deep learning and the interpretability of case-based reasoning. This model classifies input images by…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Jon Donnelly , Alina Jade Barnett , Chaofan Chen

Many interpretable AI approaches have been proposed to provide plausible explanations for a model's decision-making. However, configuring an explainable model that effectively communicates among computational modules has received less…

Machine Learning · Computer Science 2023-11-09 Jinyung Hong , Keun Hee Park , Theodore P. Pavlic

One of the major challenges in machine learning nowadays is to provide predictions with not only high accuracy but also user-friendly explanations. Although in recent years we have witnessed increasingly popular use of deep neural networks…

Machine Learning · Computer Science 2019-07-24 Yao Ming , Panpan Xu , Huamin Qu , Liu Ren

Deep networks that rely on prototypes-interpretable representations that can be related to the model input-have gained significant attention for balancing high accuracy with inherent interpretability, which makes them suitable for critical…

Machine Learning · Computer Science 2026-04-20 Mohammad Mahdi Abootorabi , Parvin Mousavi , Purang Abolmaesumi , Evan Shelhamer

The interpretability of neural networks has recently received extensive attention. Previous prototype-based explainable networks involved prototype activation in both reasoning and interpretation processes, requiring specific explainable…

Computer Vision and Pattern Recognition · Computer Science 2022-11-22 Yitao Peng , Yihang Liu , Longzhen Yang , Lianghua He

Prototypical part network (ProtoPNet) has drawn wide attention and boosted many follow-up studies due to its self-explanatory property for explainable artificial intelligence (XAI). However, when directly applying ProtoPNet on vision…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Mengqi Xue , Qihan Huang , Haofei Zhang , Jingwen Hu , Jie Song , Mingli Song , Canghong Jin

Prostate cancer being one of the frequently diagnosed malignancy in men, the rising demand for biopsies places a severe workload on pathologists. The grading procedure is tedious and subjective, motivating the development of automated…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Riddhasree Bhattacharyya , Pallabi Dutta , Sushmita Mitra

Recent advancements in post-hoc and inherently interpretable methods have markedly enhanced the explanations of black box classifier models. These methods operate either through post-analysis or by integrating concept learning during model…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 Bor-Shiun Wang , Chien-Yi Wang , Wei-Chen Chiu

Automated diagnosis with artificial intelligence has emerged as a promising area in the realm of medical imaging, while the interpretability of the introduced deep neural networks still remains an urgent concern. Although contemporary…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Binghua Li , Jie Mao , Zhe Sun , Chao Li , Qibin Zhao , Toshihisa Tanaka

Remote screening of respiratory diseases has been widely studied as a non-invasive and early instrument for diagnosis purposes, especially in the pandemic. The respiratory sound classification task has been realized with numerous deep…

Sound · Computer Science 2022-02-08 Zhao Ren , Thanh Tam Nguyen , Wolfgang Nejdl

Predictive uncertainty-a model's self awareness regarding its accuracy on an input-is key for both building robust models via training interventions and for test-time applications such as selective classification. We propose a novel…

Machine Learning · Computer Science 2024-01-04 Nishant Jain , Karthikeyan Shanmugam , Pradeep Shenoy
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