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Related papers: Developing a Knowledge Graph Framework for Pharmac…

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Biomedical knowledge graphs (KGs) are widely used across research and translational settings, yet their design decisions and implementation are often opaque. Unlike ontologies that more frequently adhere to established creation principles,…

Large language models (LLMs) offer new opportunities for constructing knowledge graphs (KGs) from unstructured clinical narratives. However, existing approaches often rely on structured inputs and lack robust validation of factual accuracy…

Artificial Intelligence · Computer Science 2026-01-06 Udiptaman Das , Krishnasai B. Atmakuri , Duy Ho , Chi Lee , Yugyung Lee

Knowledge graphs (KGs) are important products of the semantic web, which are widely used in various application domains. Healthcare is one of such domains where KGs are intensively used, due to the high requirement for knowledge accuracy…

Artificial Intelligence · Computer Science 2025-07-31 Yuzhang Xie , Xu Han , Ran Xu , Xiao Hu , Jiaying Lu , Carl Yang

Knowledge graphs (KGs) have become the preferred technology for representing, sharing and adding knowledge to modern AI applications. While KGs have become a mainstream technology, the RDF/SPARQL-centric toolset for operating with them at…

Knowledge graph (KG) enhanced recommendation has demonstrated improved performance in the recommendation system (RecSys) and attracted considerable research interest. Recently the literature has adopted neural graph networks (GNNs) on the…

Information Retrieval · Computer Science 2022-11-15 Liangwei Yang , Shen Wang , Jibing Gong , Shaojie Zheng , Shuying Du , Zhiwei Liu , Philip S. Yu

This comprehensive review aims to provide an overview of the current state of Healthcare Knowledge Graphs (HKGs), including their construction, utilization models, and applications across various healthcare and biomedical research domains.…

Patient-Centric Knowledge Graphs (PCKGs) represent an important shift in healthcare that focuses on individualized patient care by mapping the patient's health information in a holistic and multi-dimensional way. PCKGs integrate various…

This paper presents an ecosystem for personal knowledge graphs (PKGs), commonly defined as resources of structured information about entities related to an individual, their attributes, and the relations between them. PKGs are a key enabler…

Artificial Intelligence · Computer Science 2024-03-18 Martin G. Skjæveland , Krisztian Balog , Nolwenn Bernard , Weronika Łajewska , Trond Linjordet

Knowledge Graphs (KGs), as structured knowledge bases that organize relational information across diverse domains, provide a unified semantic foundation for cross-domain recommendation (CDR). By integrating symbolic knowledge with user-item…

Information Retrieval · Computer Science 2025-11-05 Yuhan Wang , Qing Xie , Zhifeng Bao , Mengzi Tang , Lin Li , Yongjian Liu

Much of human knowledge in cybersecurity is encapsulated within the ever-growing volume of scientific papers. As this textual data continues to expand, the importance of document organization methods becomes increasingly crucial for…

Accurate prediction of drug-target interaction (DTI) is essential for in silico drug design. For the purpose, we propose a novel approach for predicting DTI using a GNN that directly incorporates the 3D structure of a protein-ligand…

Machine Learning · Computer Science 2019-04-18 Jaechang Lim , Seongok Ryu , Kyubyong Park , Yo Joong Choe , Jiyeon Ham , Woo Youn Kim

Personal Knowledge Graphs (PKGs) are introduced by the semantic web community as small-sized user-centric knowledge graphs (KGs). PKGs fill the gap of personalised representation of user data and interests on the top of big,…

Information Retrieval · Computer Science 2022-03-17 Eleni Ilkou

Motivation: Computational prediction of multiple-type drug-drug interaction (DDI) helps reduce unexpected side effects in poly-drug treatments. Although existing computational approaches achieve inspiring results, they ignore that the…

Machine Learning · Computer Science 2021-12-07 Hui Yu , ShiYu Zhao , JianYu Shi

Conversational Question Answering over Knowledge Graphs (KGs) combines the factual grounding of KG-based QA with the interactive nature of dialogue systems. KGs are widely used in enterprise and domain applications to provide structured,…

Computation and Language · Computer Science 2025-11-27 Reham Omar , Abdelghny Orogat , Ibrahim Abdelaziz , Omij Mangukiya , Panos Kalnis , Essam Mansour

Gene/protein interactions provide critical information for a thorough understanding of cellular processes. Recently, considerable interest and effort has been focused on the construction and analysis of genome-wide gene networks. The large…

Molecular Networks · Quantitative Biology 2022-04-25 Xin Li , Hsinchun Chen , Zan Huang , Hua Su , Jesse D. Martinez

Protein-ligand interactions (PLIs) are fundamental to biochemical research and their identification is crucial for estimating biophysical and biochemical properties for rational therapeutic design. Currently, experimental characterization…

Machine Learning · Statistics 2021-12-01 Carter Knutson , Mridula Bontha , Jenna A. Bilbrey , Neeraj Kumar

With the advance of natural language inference (NLI), a rising demand for NLI is to handle scientific texts. Existing methods depend on pre-trained models (PTM) which lack domain-specific knowledge. To tackle this drawback, we introduce a…

Computation and Language · Computer Science 2022-10-31 Chenglin Wang , Yucheng Zhou , Guodong Long , Xiaodong Wang , Xiaowei Xu

Knowledge graphs (KGs) contain rich information about world knowledge, entities and relations. Thus, they can be great supplements to existing pre-trained language models. However, it remains a challenge to efficiently integrate information…

Computation and Language · Computer Science 2020-10-05 Donghan Yu , Chenguang Zhu , Yiming Yang , Michael Zeng

Predicting signed interactions in biological networks is crucial for understanding drug mechanisms and facilitating drug repurposing. While deep graph models have demonstrated success in modeling complex biological systems, existing…

Machine Learning · Computer Science 2025-03-19 Shuyi Jin , Mengji Zhang , Meijie Wang , Lun Yu

PubMed is an essential resource for the medical domain, but useful concepts are either difficult to extract or are ambiguated, which has significantly hindered knowledge discovery. To address this issue, we constructed a PubMed knowledge…