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Molecular self-assembly is a well-known technique to create highly functional nanostructures on surfaces. Self-assembly on two-dimensional materials is a developing field and has already resulted in the discovery of several rich and…

Mesoscale and Nanoscale Physics · Physics 2017-09-04 Avijit Kumar , Kaustuv Banerjee , Peter Liljeroth

Biological systems exploit self-assembly to create complex structures whose arrangements are finely controlled from molecular to mesoscopic level. Herein we report an example of using fully synthetic systems that mimic two levels of…

Establishing precise control over the shape and the interactions of the microscopic building blocks is essential for design of macroscopic soft materials with novel structural, optical and mechanical properties. Here, we demonstrate robust…

Simple local interactions can cause primitive building blocks to self-assemble into complex and functional patterns. However, even for a small number of blocks, there exist a vast number of possible configurations that are plausible,…

Soft Condensed Matter · Physics 2024-12-31 Audrey A. Watkins , Osama R. Bilal

We introduce allostery-mimetic building blocks model for self-assembly of 3D structures. We represent the building blocks as patchy particles, where each binding site (patch) can be irreversibly activated or deactivated by binding of the…

Computational Physics · Physics 2024-03-19 Joshua Evans , Petr Šulc

Harnessing the intrinsic dynamics of physical systems for information processing opens new avenues for computation embodied in matter. Using simulations of a model system, we show that assemblies of DNA tiles capable of self-organizing into…

Soft Condensed Matter · Physics 2025-10-23 Tim E. Veenstra , René van Roij , Marjolein Dijkstra

Evolution in time-varying environments naturally leads to adaptable biological systems that can easily switch functionalities. Advances in the synthesis of environmentally-responsive materials therefore open up the possibility of creating a…

Controlling the size and shape of assembled structures is a fundamental challenge in self-assembly, and is highly relevant in material design and biology. Here, we show that specific, but promiscuous, short-range binding interactions make…

Soft Condensed Matter · Physics 2025-07-08 Maximilian C. Hübl , Carl P. Goodrich

Self-organized complex structures in nature, e.g. viral capsids, hierarchical biopolymers, and bacterial flagella, offer efficiency, adaptability, robustness, and multi-functionality. Can we program the self-assembly of three-dimensional…

Soft Condensed Matter · Physics 2022-01-11 Francesco Serafin , Jun Lu , Nicholas Kotov , Kai Sun , Xiaoming Mao

Polymer filaments form the foundation of biology from cell scaffolding to DNA. Their study and fabrication play an important role in a wide range of processes from tissue engineering to molecular machines. We present a simple method to…

We develop a multi-scale approach to simulate hydrated nanobio systems under realistic condi- tions (e.g., nanoparticles and protein solutions at physiological conditions over time-scales up to hours). We combine atomistic simulations of…

Soft Condensed Matter · Physics 2017-07-05 Oriol Vilanova , Valentino Bianco , Giancarlo Franzese

Branched molecules of deoxyribonucleic acid (DNA) can self-assemble into nanostructures through complementary cohesive strand base pairing. The production of DNA nanostructures is valuable in targeted drug delivery and biomolecular…

Combinatorics · Mathematics 2022-03-15 D. Chloe Griffin , Jessica Sorrells

DNA self-assembly is an important tool that has a wide range of applications such as building nanostructures, the transport of target virotherapies, and nano-circuitry. Tools from graph theory can be used to encode the biological process of…

Combinatorics · Mathematics 2023-10-09 Cory Johnson , Andrew Lavengood-Ryan

Self-assembly in natural and synthetic molecular systems can create complex aggregates or materials whose properties and functionality rises from their internal structure and molecular arrangement. The key microscopic features that control…

Soft Condensed Matter · Physics 2021-09-03 Alberto Scacchi , Maria Sammalkorpi , Tapio Ala-Nissila

Geometric frustration offers a pathway to soft matter self-assembly with controllable finite sizes. While the understanding of frustration in soft matter assembly derives almost exclusively from continuum elastic descriptions, a current…

Soft Condensed Matter · Physics 2023-08-08 Douglas M. Hall , Mark J. Stevens , Gregory M. Grason

DNA self-assembly is a robust and programmable approach for building structures at nanoscale. Researchers around the world have proposed and implemented different techniques to build two dimensional and three dimensional nano structures.…

Emerging Technologies · Computer Science 2014-05-19 Shikhar Kumar Gupta , Foram Joshi , Dixita Limbachiya , Manish K Gupta

Self-assembly is a process which is ubiquitous in natural, especially biological systems. It occurs when groups of relatively simple components spontaneously combine to form more complex structures. While such systems have inspired a large…

Computational Geometry · Computer Science 2018-07-19 Jerome Durand-Lose , Jacob Hendricks , Matthew J. Patitz , Ian Perkins , Michael Sharp

In living cells, proteins self-assemble into large functional structures based on specific interactions between molecularly complex patches. Due to this complexity, protein self-assembly results from a competition between a large number of…

Soft Condensed Matter · Physics 2024-12-10 Lara Koehler , Pierre Ronceray , Martin Lenz

The mechanism and driving forces of chromosome segregation in the bacterial cell cycle of E. coli is one of the least understood events in its life cycle. Using principles of entropic repulsion between polymer loops confined in a cylinder,…

Soft Condensed Matter · Physics 2021-12-24 Debarshi Mitra , Shreerang Pande , Apratim Chatterji

The design of complex materials and the formation of specific patterns often arise from the properties of the individual building blocks. In this respect, colloidal systems offer a unique opportunity because nowadays they can be synthesized…

Soft Condensed Matter · Physics 2022-03-01 Fabrizio Camerin , Emanuela Zaccarelli