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Multiplex brightfield imaging offers the advantage of simultaneously analyzing multiple biomarkers on a single slide, as opposed to single biomarker labeling on multiple consecutive slides. To accurately analyze multiple biomarkers…
Microscopy images obtained from multiple camera lenses or sensors in biological experiments provide a comprehensive understanding of objects from diverse perspectives. However, using multiple microscope setups increases the risk of…
We present a method for simultaneously learning, in an unsupervised manner, (i) a conditional image generator, (ii) foreground extraction and segmentation, (iii) clustering into a two-level class hierarchy, and (iv) object removal and…
X-ray computed tomography (CT) uses different filter kernels to highlight different structures. Since the raw sinogram data is usually removed after the reconstruction, in case there are additional need for other types of kernel images that…
In many fields, self-supervised learning solutions are rapidly evolving and filling the gap with supervised approaches. This fact occurs for depth estimation based on either monocular or stereo, with the latter often providing a valid…
By circumventing the resolution limitations of optics, coherent diffractive imaging (CDI) and ptychography are making their way into scientific fields ranging from X-ray imaging to astronomy. Yet, the need for time consuming iterative phase…
Lightsheet microscopy is a powerful 3-D imaging technique that addresses limitations of traditional optical and confocal microscopy but suffers from a low penetration depth and reduced image quality at greater depths. Multiview lightsheet…
The availability of large-scale datasets has helped unleash the true potential of deep convolutional neural networks (CNNs). However, for the single-image denoising problem, capturing a real dataset is an unacceptably expensive and…
Neural networks are a general framework for differentiable optimization which includes many other machine learning approaches as special cases. In this paper we build a category-theoretic formalism around a neural network system called…
Image registration is a fundamental task in medical image analysis. Recently, deep learning based image registration methods have been extensively investigated due to their excellent performance despite the ultra-fast computational time.…
While the keypoint-based maps created by sparse monocular simultaneous localisation and mapping (SLAM) systems are useful for camera tracking, dense 3D reconstructions may be desired for many robotic tasks. Solutions involving depth cameras…
Real-world face super-resolution (SR) is a highly ill-posed image restoration task. The fully-cycled Cycle-GAN architecture is widely employed to achieve promising performance on face SR, but prone to produce artifacts upon challenging…
Electron microscopy (EM) images exhibit anisotropic axial resolution due to the characteristics inherent to the imaging modality, presenting challenges in analysis and downstream tasks.In this paper, we propose a diffusion-model-based…
Computed tomography (CT) is widely used in screening, diagnosis, and image-guided therapy for both clinical and research purposes. Since CT involves ionizing radiation, an overarching thrust of related technical research is development of…
Generative Adversarial Networks (GANs) triggered an increased interest in problem of image generation due to their improved output image quality and versatility for expansion towards new methods. Numerous GAN-based works attempt to improve…
Deep learning-based image reconstruction approaches have demonstrated impressive empirical performance in many imaging modalities. These approaches usually require a large amount of high-quality paired training data, which is often not…
The variation in histologic staining between different medical centers is one of the most profound challenges in the field of computer-aided diagnosis. The appearance disparity of pathological whole slide images causes algorithms to become…
Research exploring CycleGAN-based synthetic image generation has recently accelerated in the medical community, as it is able to leverage unpaired datasets effectively. However, clinical acceptance of these synthetic images pose a…
Intraoperative optical imaging is essential for surgical precision and patient safety, but current systems present anatomical and fluorescence information separately, causing delays and increasing cognitive load. A unified system for…
Convolutional Neural Networks (CNN)-based approaches have shown promising results in pansharpening of satellite images in recent years. However, they still exhibit limitations in producing high-quality pansharpening outputs. To that end, we…