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Related papers: Nonparametric clustering of RNA-sequencing data

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Missing values frequently arise in modern biomedical studies due to various reasons, including missing tests or complex profiling technologies for different omics measurements. Missing values can complicate the application of clustering…

Machine Learning · Statistics 2019-02-27 Shahin Boluki , Siamak Zamani Dadaneh , Xiaoning Qian , Edward R. Dougherty

A mixture of joint generalized hyperbolic distributions (MJGHD) is introduced for asymmetric clustering for high-dimensional data. The MJGHD approach takes into account the cluster-specific subspace, thereby limiting the number of…

Methodology · Statistics 2018-11-02 Yang Tang , Ryan P. Browne , Paul D. McNicholas

In the context of clustering, we assume a generative model where each cluster is the result of sampling points in the neighborhood of an embedded smooth surface; the sample may be contaminated with outliers, which are modeled as points…

Machine Learning · Statistics 2011-11-30 Ery Arias-Castro , Guangliang Chen , Gilad Lerman

We study the problem of applying spectral clustering to cluster multi-scale data, which is data whose clusters are of various sizes and densities. Traditional spectral clustering techniques discover clusters by processing a similarity…

Machine Learning · Computer Science 2020-06-09 Xiang Li , Ben Kao , Caihua Shan , Dawei Yin , Martin Ester

A probabilistic clustering algorithm is proposed for the analysis of forensic DNA mixtures in which individual cells are isolated and short tandem repeats are amplified using the polymerase chain reaction to generate single cell…

Applications · Statistics 2025-10-14 Robert G. Cowell

In this article, we propose two classes of semiparametric mixture regression models with single-index for model based clustering. Unlike many semiparametric/nonparametric mixture regression models that can only be applied to low dimensional…

Methodology · Statistics 2017-08-15 Sijia Xiang , Weixin Yao

The interpretation of unlabeled acoustic emission (AE) data classically relies on general-purpose clustering methods. While several external criteria have been used in the past to select the hyperparameters of those algorithms, few studies…

Machine Learning · Statistics 2022-11-29 Emmanuel Ramasso , Thierry Denoeux , Gael Chevallier

Modern network analysis often involves multi-layer network data in which the nodes are aligned, and the edges on each layer represent one of the multiple relations among the nodes. Current literature on multi-layer network data is mostly…

Statistics Theory · Mathematics 2024-06-18 Wenqing Su , Xiao Guo , Xiangyu Chang , Ying Yang

Clustering is a widely deployed unsupervised learning tool. Model-based clustering is a flexible framework to tackle data heterogeneity when the clusters have different shapes. Likelihood-based inference for mixture distributions often…

Machine Learning · Statistics 2023-05-30 Yubo Zhuang , Xiaohui Chen , Yun Yang

Mixture of autoregressions (MoAR) models provide a model-based approach to the clustering of time series data. The maximum likelihood (ML) estimation of MoAR models requires the evaluation of products of large numbers of densities of normal…

Computation · Statistics 2016-10-19 Hien D Nguyen , Geoffrey J McLachlan , Pierre Orban , Pierre Bellec , Andrew L Janke

As in other estimation scenarios, likelihood based estimation in the normal mixture set-up is highly non-robust against model misspecification and presence of outliers (apart from being an ill-posed optimization problem). A robust…

Methodology · Statistics 2023-12-20 Soumya Chakraborty , Ayanendranath Basu , Abhik Ghosh

The increasing availability of multiple network data has highlighted the need for statistical models for heterogeneous populations of networks. A convenient framework makes use of metrics to measure similarity between networks. In this…

Methodology · Statistics 2026-03-09 Francesco Barile , Simón Lunagómez , Bernardo Nipoti

Although distance measures are used in many machine learning algorithms, the literature on the context-independent selection and evaluation of distance measures is limited in the sense that prior knowledge is used. In cluster analysis,…

Machine Learning · Computer Science 2021-08-24 Michael C. Thrun

Clustering is one of the widely used data mining techniques for medical diagnosis. Clustering can be considered as the most important unsupervised learning technique. Most of the clustering methods group data based on distance and few…

Machine Learning · Computer Science 2012-12-24 K. Dhanalakshmi , H. Hannah Inbarani

We propose a joint channel estimation and signal detection technique for the uplink non-orthogonal multiple access using an unsupervised clustering approach. We apply the Gaussian mixture model to cluster received signals and accordingly…

Signal Processing · Electrical Eng. & Systems 2020-10-08 Ayoob Salari , Mahyar Shirvanimoghaddam , Muhammad Basit Shahab , Reza Arablouei , Sarah Johnson

Cut-based directed graph (digraph) clustering often focuses on finding dense within-cluster or sparse between-cluster connections, similar to cut-based undirected graph clustering methods. In contrast, for flow-based clusterings the edges…

Machine Learning · Computer Science 2022-03-04 Koby Hayashi , Sinan G. Aksoy , Haesun Park

Linear mixed models (LMMs) are used as an important tool in the data analysis of repeated measures and longitudinal studies. The most common form of LMMs utilize a normal distribution to model the random effects. Such assumptions can often…

Methodology · Statistics 2016-02-16 Hien D. Nguyen , Geoffrey J. McLachlan

Directed networks are broadly used to represent asymmetric relationships among units. Co-clustering aims to cluster the senders and receivers of directed networks simultaneously. In particular, the well-known spectral clustering algorithm…

Machine Learning · Statistics 2022-04-12 Xiao Guo , Yixuan Qiu , Hai Zhang , Xiangyu Chang

Co-clustering is a specific type of clustering that addresses the problem of finding groups of objects without necessarily considering all attributes. This technique has shown to have more consistent results in high-dimensional sparse data…

Machine Learning · Computer Science 2021-10-28 Yuri Santos , Jônata Tyska , Vania Bogorny

In this paper we develop a nonparametric maximum likelihood estimate of the mixing distribution of the parameters of a linear stochastic dynamical system. This includes, for example, pharmacokinetic population models with process and…

Methodology · Statistics 2015-09-16 Alona Kryshchenko , Alan Schumitzky , Mike van Guilder , Michael Neely
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