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We have seen significant leapfrog advancement in machine learning in recent decades. The central idea of machine learnability lies on constructing learning algorithms that learn from good data. The availability of more data being made…

Computer Vision and Pattern Recognition · Computer Science 2020-08-07 Ng Hui Xian Lynnette , Henry Ng Siong Hock , Nguwi Yok Yen

Cell tracking remains a pivotal yet challenging task in biomedical research. The full potential of deep learning for this purpose is often untapped due to the limited availability of comprehensive and varied training data sets. In this…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Moritz Sturm , Lorenzo Cerrone , Fred A. Hamprecht

Analysis of microscopy images can provide insight into many biological processes. One particularly challenging problem is cell nuclear segmentation in highly anisotropic and noisy 3D image data. Manually localizing and segmenting each and…

Computer Vision and Pattern Recognition · Computer Science 2013-09-18 Christian Widmer , Philipp Drewe , Xinghua Lou , Shefali Umrania , Stephanie Heinrich , Gunnar Rätsch

Recently, researchers in Machine Learning algorithms, Computer Vision scientists, engineers and others, showed a growing interest in 3D simulators as a mean to artificially create experimental settings that are very close to those in the…

Computer Vision and Pattern Recognition · Computer Science 2022-10-18 Enrico Meloni , Luca Pasqualini , Matteo Tiezzi , Marco Gori , Stefano Melacci

Object segmentation is an important step in the workflow of computational pathology. Deep learning based models generally require large amount of labeled data for precise and reliable prediction. However, collecting labeled data is…

Computer Vision and Pattern Recognition · Computer Science 2020-07-08 Navid Alemi Koohbanani , Mostafa Jahanifar , Neda Zamani Tajadin , Nasir Rajpoot

Multimodal Large Language Models (MLLMs) have shown promise in a broad range of vision-language tasks with their strong reasoning and generalization capabilities. However, they heavily depend on high-quality data in the Supervised…

Computer Vision and Pattern Recognition · Computer Science 2024-09-23 Jing Hao , Yuxiang Zhao , Song Chen , Yanpeng Sun , Qiang Chen , Gang Zhang , Kun Yao , Errui Ding , Jingdong Wang

Fluorescent Neuronal Cells v2 is a collection of fluorescence microscopy images and the corresponding ground-truth annotations, designed to foster innovative research in the domains of Life Sciences and Deep Learning. This dataset…

Cell segmentation in microscopy is a challenging problem, since cells are often asymmetric and densely packed. This becomes particularly challenging for extremely large images, since manual intervention and processing time can make…

Image and Video Processing · Electrical Eng. & Systems 2019-06-19 Mahsa Lotfollahi , Sebastian Berisha , Leila Saadatifard , Laura Montier , Jokubas Ziburkus , David Mayerich

The emergence of multicellularity and developmental programs are among the major problems of evolutionary biology. Traditionally, research in this area has been based on the combination of data analysis and experimental work on one hand and…

Populations and Evolution · Quantitative Biology 2014-03-14 Ricard V. Solé , Salva Duran-Nebreda

We introduce altiro3D, a free extended library developed to represent reality starting from a given original RGB image or flat video. It allows to generate a light-field (or Native) image or video and get a realistic 3D experience. To…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 E. Canessa , L. Tenze

This chapter provides a brief introduction to the theory and practice of spatial stochastic simulations. It begins with an overview of different methods available for biochemical simulations highlighting their strengths and limitations.…

Quantitative Methods · Quantitative Biology 2018-10-02 Sanjana Gupta , Jacob Czech , Robert Kuczewski , Thomas M. Bartol , Terrence J. Sejnowski , Robin E. C. Lee , James R. Faeder

The accurate tracking of live cells using video microscopy recordings remains a challenging task for popular state-of-the-art image processing based object tracking methods. In recent years, several existing and new applications have…

Image and Video Processing · Electrical Eng. & Systems 2025-02-03 Gergely Szabó , Paolo Bonaiuti , Andrea Ciliberto , András Horváth

With the growth of artificial intelligence (AI), there has been an increase in the adoption of computer vision and deep learning (DL) techniques for the evaluation of microscopy images and movies. This adoption has not only addressed…

Quantitative Methods · Quantitative Biology 2023-07-21 Binghao Chai , Christoforos Efstathiou , Haoran Yue , Viji M. Draviam

Semantic segmentation is a crucial task in biomedical image processing, which recent breakthroughs in deep learning have allowed to improve. However, deep learning methods in general are not yet widely used in practice since they require…

Computer Vision and Pattern Recognition · Computer Science 2019-07-12 Melanie Lubrano di Scandalea , Christian S. Perone , Mathieu Boudreau , Julien Cohen-Adad

Instance segmentation enables the analysis of spatial and temporal properties of cells in microscopy images by identifying the pixels belonging to each cell. However, progress is constrained by the scarcity of high-quality labeled…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Kaden Stillwagon , Alexandra Dunnum VandeLoo , Benjamin Magondu , Craig R. Forest

AI models rely on annotated data to learn pattern and perform prediction. Annotation is usually a labor-intensive step that require associating labels ranging from a simple classification label to more complex tasks such as object…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Safouane El Ghazouali , Umberto Michelucci

Frontier multimodal large language models (MLLMs) have been reported to achieve over 90% accuracy on fine-grained perception benchmarks. However, such scores do not necessarily imply faithful use of visual evidence. Prior studies have…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Jingru Chen , Yiming Liu , Mingtao Chen , Sijie Chen , Richeng Xuan , Liang Yang , Zhichao Hu , Fanyang Lu

Availability of a few, large-size, annotated datasets, like ImageNet, Pascal VOC and COCO, has lead deep learning to revolutionize computer vision research by achieving astonishing results in several vision tasks.We argue that new tools to…

Computer Vision and Pattern Recognition · Computer Science 2020-10-27 Pierluigi Zama Ramirez , Claudio Paternesi , Luca De Luigi , Luigi Lella , Daniele De Gregorio , Luigi Di Stefano

In today's world of big data, computational analysis has become a key driver of biomedical research. Recent exponential growth in the volume of available omics data has reshaped the landscape of contemporary biology, creating demand for a…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-12-09 Jaqueline J. Brito , Thiago Mosqueiro , Jeremy Rotman , Victor Xue , Douglas J. Chapski , Juan De la Hoz , Paulo Matias , Lana Martin , Alex Zelikovsky , Matteo Pellegrinni , Serghei Mangul

In recent years, deep learning has become a breakthrough technique in assisting medical image diagnosis. Supervised learning using convolutional neural networks (CNN) provides state-of-the-art performance and has served as a benchmark for…

Image and Video Processing · Electrical Eng. & Systems 2023-06-30 Tao Wang , Xinlin Zhang , Yuanbo Zhou , Junlin Lan , Tao Tan , Min Du , Qinquan Gao , Tong Tong