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Diabetic retinopathy (DR) is a leading cause of vision loss, requiring early and accurate assessment to prevent irreversible damage. Spectral Domain Optical Coherence Tomography (SD-OCT) enables high-resolution retinal imaging, but…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 S. Chen , D. Ma , M. Raviselvan , S. Sundaramoorthy , K. Popuri , M. J. Ju , M. V. Sarunic , D. Ratra , M. F. Beg

Foundation models are large-scale versatile systems trained on vast quantities of diverse data to learn generalizable representations. Their adaptability with minimal fine-tuning makes them particularly promising for medical imaging, where…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 Lucie Berger , Mathieu Lamard , Philippe Zhang , Laurent Borderie , Alexandre Le Guilcher , Pascale Massin , Béatrice Cochener , Gwenolé Quellec , Sarah Matta

Alterations in retinal layer thickness, measurable using Optical Coherence Tomography (OCT), have been associated with neurodegenerative diseases such as Alzheimer's disease (AD). While previous studies have mainly focused on segmented…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Yasemin Turkan , F. Boray Tek , M. Serdar Nazlı , Öykü Eren

Prior skin image datasets have not addressed patient-level information obtained from multiple skin lesions from the same patient. Though artificial intelligence classification algorithms have achieved expert-level performance in controlled…

Lipid droplets (LDs) are subcellular organelles with important roles in lipid storage and metabolism and involved in various diseases including cancer, obesity, and diabetes. Conventional methods, however, have limited ability to provide…

Biological Physics · Physics 2016-11-08 Kyoohyun Kim , SeoEun Lee , Jonghee Yoon , JiHan Heo , Chulhee Choi , YongKeun Park

With the advancement of deep learning techniques, an increasing number of methods have been proposed for optic disc and cup (OD/OC) segmentation from the fundus images. Clinically, OD/OC segmentation is often annotated by multiple clinical…

Image and Video Processing · Electrical Eng. & Systems 2022-09-20 Junde Wu , Huihui Fang , Dalu Yang , Zhaowei Wang , Wenshuo Zhou , Fangxin Shang , Yehui Yang , Yanwu Xu

Diabetic macular edema (DME) is a severe complication of diabetes, characterized by thickening of the central portion of the retina due to accumulation of fluid. DME is a significant and common cause of visual impairment in diabetic…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Pengyao Qin , Arun J. Thirunavukarasu , Theodoros Arvanitis , Le Zhang

Purpose: (1) To develop a deep learning algorithm to identify major tissue structures of the optic nerve head (ONH) in 3D optical coherence tomography (OCT) scans; (2) to exploit such information to robustly differentiate among healthy,…

Machine Learning (ML) is used to tackle various tasks, such as disease classification and prediction. The effectiveness of ML models relies heavily on having large amounts of complete data. However, healthcare data is often limited or…

Retinal vessel segmentation is generally grounded in image-based datasets collected with bench-top devices. The static images naturally lose the dynamic characteristics of retina fluctuation, resulting in diminished dataset richness, and…

Diabetic Retinopathy (DR) has become one of the leading causes of vision impairment in working-aged people and is a severe problem worldwide. However, most of the works ignored the ordinal information of labels. In this project, we propose…

Computer Vision and Pattern Recognition · Computer Science 2022-10-31 Chao Feng , Jui Po Hung , Aishan Li , Jieping Yang , Xinyu Zhang

Optical Coherence Tomography (OCT) layer segmentation faces challenges due to annotation scarcity and heterogeneous label granularities across datasets. While semi-supervised learning helps alleviate label scarcity, existing methods…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yizhou Fang , Jian Zhong , Li Lin , Xiaoying Tang

Multiple instance learning (MIL) is a supervised learning methodology that aims to allow models to learn instance class labels from bag class labels, where a bag is defined to contain multiple instances. MIL is gaining traction for learning…

Computer Vision and Pattern Recognition · Computer Science 2019-11-14 Samuel W. Remedios , Zihao Wu , Camilo Bermudez , Cailey I. Kerley , Snehashis Roy , Mayur B. Patel , John A. Butman , Bennett A. Landman , Dzung L. Pham

Early detection of retinal diseases is one of the most important means of preventing partial or permanent blindness in patients. In this research, a novel multi-label classification system is proposed for the detection of multiple retinal…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 M. A. Rodriguez , H. AlMarzouqi , P. Liatsis

Surgical scene perception via videos is critical for advancing robotic surgery, telesurgery, and AI-assisted surgery, particularly in ophthalmology. However, the scarcity of diverse and richly annotated video datasets has hindered the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Ming Hu , Peng Xia , Lin Wang , Siyuan Yan , Feilong Tang , Zhongxing Xu , Yimin Luo , Kaimin Song , Jurgen Leitner , Xuelian Cheng , Jun Cheng , Chi Liu , Kaijing Zhou , Zongyuan Ge

Interpretability is a key factor in the design of automatic classifiers for medical diagnosis. Deep learning models have been proven to be a very effective classification algorithm when trained in a supervised way with enough data. The main…

Machine Learning · Statistics 2018-09-25 Jordi de la Torre , Aida Valls , Domenec Puig , Pere Romero-Aroca

We present a new dataset with annotated eye movements. The dataset consists of over 800,000 gaze points recorded during a car ride in the real world and in the simulator. In total, the eye movements of 19 subjects were annotated. In this…

Computer Vision and Pattern Recognition · Computer Science 2021-01-13 Wolfgang Fuhl , Enkelejda Kasneci

Medical vision-language models (VLMs) excel at image-text understanding but typically rely on a single-pass reasoning that neglects localized visual cues. In clinical practice, however, human experts iteratively scan, focus, and refine the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Kaitao Chen , Shaohao Rui , Yankai Jiang , Jiamin Wu , Qihao Zheng , Chunfeng Song , Xiaosong Wang , Mu Zhou , Mianxin Liu

Purpose: To evaluate Pegasus-OCT, a clinical decision support software for the identification of features of retinal disease from macula OCT scans, across heterogenous populations involving varying patient demographics, device…

Image and Video Processing · Electrical Eng. & Systems 2019-07-12 Kanwal K. Bhatia , Mark S. Graham , Louise Terry , Ashley Wood , Paris Tranos , Sameer Trikha , Nicolas Jaccard

Background: Several studies indicate that the anterior visual pathway provides information about the dynamics of axonal degeneration in Multiple Sclerosis (MS). Current research in the field is focused on the quest for the most…

Image and Video Processing · Electrical Eng. & Systems 2023-02-15 Monica Hernandez , Ubaldo Ramon-Julvez , Elisa Vilades , Beatriz Cordon , Elvira Mayordomo , Elena Garcia-Martin
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