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Optimizing the mRNA codon has an essential impact on gene expression for a specific target protein. It is an NP-hard problem; thus, exact solutions to such optimization problems become computationally intractable for realistic problem sizes…

Quantum Physics · Physics 2024-05-13 Hongfeng Zhang , Aritra Sarkar , Koen Bertels

Neuroscientists face challenges in analyzing high-dimensional neural recording data of dense functional networks. Without ground-truth reference data, finding the best algorithm for recovering neurologically relevant networks remains an…

Quantum Physics · Physics 2025-08-28 Skylar Chan , Wilson Smith , Kyla Gabriel

Variational quantum algorithms constitute one of the most widespread methods for using current noisy quantum computers. However, it is unknown if these heuristic algorithms provide any quantum-computational speedup, although we cannot…

Quantum algorithms for computational linear algebra promise up to exponential speedups for applications such as simulation and regression, making them prime candidates for hardware realization. But these algorithms execute in a model that…

Programming Languages · Computer Science 2026-05-14 Charles Yuan

Quantum computing can enable a variety of breakthroughs in research and industry in the future. Although some quantum algorithms already exist that show a theoretical speedup compared to the best known classical algorithms, the…

Quantum Physics · Physics 2020-12-14 Marie Salm , Johanna Barzen , Uwe Breitenbücher , Frank Leymann , Benjamin Weder , Karoline Wild

Analytical and practical evidence indicates the advantage of quantum computing solutions over classical alternatives. Quantum-based heuristics relying on the variational quantum eigensolver (VQE) and the quantum approximate optimization…

Quantum Physics · Physics 2023-01-05 Sarthak Gupta , Vassilis Kekatos

Quantum computing is a promising paradigm that may overcome the current computational power bottlenecks. The increasing maturity of quantum processors provides more possibilities for the development and implementation of quantum algorithms.…

Quantum Physics · Physics 2025-10-15 Ge Yan , Wenjie Wu , Yuheng Chen , Kaisen Pan , Xudong Lu , Zixiang Zhou , Yuhan Wang , Ruocheng Wang , Junchi Yan

We provide algorithms for efficiently addressing quantum memory in parallel. These imply that the standard circuit model can be simulated with low overhead by the more realistic model of a distributed quantum computer. As a result, the…

Characterization of quantum systems from experimental data is a central problem in quantum science and technology. But which measurements should be used to gather data in the first place? While optimal measurement choices can be worked out…

Quantum Physics · Physics 2025-07-15 Jiaxin Huang , Yan Zhu , Giulio Chiribella , Ya-Dong Wu

With fault-tolerant quantum computing on the horizon, there is growing interest in applying quantum computational methods to data-intensive scientific fields like remote sensing. Quantum machine learning (QML) has already demonstrated…

Quantum Physics · Physics 2026-02-24 Tomasz Rybotycki , Sebastian Dziura , Piotr Gawron

Quantum computing leverages quantum effects to build algorithms that are faster then their classical variants. In machine learning, for a given model architecture, the speed of training the model is typically determined by the size of the…

Machine Learning · Computer Science 2022-04-25 Seyran Saeedi , Aliakbar Panahi , Tom Arodz

The VQE algorithm has turned out to be quite expensive to run given the way we currently access quantum processors (i.e. over the cloud). In order to alleviate this issue, we introduce Quantum Sampling Regression (QSR), an alternative…

Quantum Physics · Physics 2020-12-07 Pedro Rivero , Ian C. Cloët , Zack Sullivan

Here we explore which heuristic quantum algorithms for combinatorial optimization might be most practical to try out on a small fault-tolerant quantum computer. We compile circuits for several variants of quantum accelerated simulated…

Quantum machine learning has established as an interdisciplinary field to overcome limitations of classical machine learning and neural networks. This is a field of research which can prove that quantum computers are able to solve problems…

Quantum Physics · Physics 2023-03-13 Meghashrita Das , Tirupati Bolisetti

We propose a Quantum Machine Learning (QML) framework that leverages quantum parallelism to process entire training datasets in a single quantum operation, addressing the computational bottleneck of sequential data processing in both…

This PhD thesis explores the potential of quantum computing to address computational challenges in high-energy physics (HEP). As the Standard Model (SM) leaves key questions unanswered and no signs of new physics have emerged since the…

Quantum Physics · Physics 2025-12-02 Jorge J. Martínez de Lejarza

A cardinal obstacle to performing quantum-mechanical simulations of strongly-correlated matter is that, with the theoretical tools presently available, sufficiently-accurate computations are often too expensive to be ever feasible. Here we…

Strongly Correlated Electrons · Physics 2021-02-10 John Rogers , Tsung-Han Lee , Sahar Pakdel , Wenhu Xu , Vladimir Dobrosavljević , Yong-Xin Yao , Ove Christiansen , Nicola Lanatà

Machine learning techniques have led to broad adoption of a statistical model of computing. The statistical distributions natively available on quantum processors are a superset of those available classically. Harnessing this attribute has…

Quantum Machine Learning (QML) has emerged as a promising framework for exploring how quantum dynamics may enhance data processing tasks. Here we investigate Quantum Extreme Learning Machines (QELMs), a quantum analogue of classical Extreme…

Quantum Physics · Physics 2026-04-27 A. De Lorenzis , M. P. Casado , N. Lo Gullo , T. Lux , F. Plastina , A. Riera

Enhancing classical machine learning (ML) algorithms through quantum kernels is a rapidly growing research topic in quantum machine learning (QML). A key challenge in using kernels -- both classical and quantum -- is that ML workflows…

Quantum Physics · Physics 2021-12-17 Annie Naveh , Imogen Fitzgerald , Anna Phan , Andrew Lockwood , Travis L. Scholten