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Sequence discovery tools play a central role in several fields of computational biology. In the framework of Transcription Factor binding studies, motif finding algorithms of increasingly high performance are required to process the big…

Quantitative Methods · Quantitative Biology 2014-08-27 Nicolò Colombo , Nikos Vlassis

Network motif algorithms have been a topic of research mainly after the 2002-seminal paper from Milo \emph{et al}, that provided motifs as a way to uncover the basic building blocks of most networks. In Bioinformatics, motifs have been…

Data Structures and Algorithms · Computer Science 2013-04-22 Luis A. A. Meira , Vinicius R. Máximo , Álvaro L. Fazenda , Arlindo F. da Conceição

Hypergraph clustering is a basic algorithmic primitive for analyzing complex datasets and systems characterized by multiway interactions, such as group email conversations, groups of co-purchased retail products, and co-authorship data.…

Data Structures and Algorithms · Computer Science 2023-01-31 Nate Veldt

Many networks in real-life typically contain parts in which some nodes are more highly connected to each other than the other nodes of the network. The collection of such nodes are usually called clusters, communities, cohesive groups or…

Distributed, Parallel, and Cluster Computing · Computer Science 2008-06-20 Xiahong Lin , Lin Gao , Kefei Chen , David K. Y. Chiu

Motifs are patterns of subgraphs of complex networks. We studied the impact of such patterns of connectivity on the level of correlated, or synchronized, spiking activity among pairs of cells in a recurrent network model of integrate and…

Neurons and Cognition · Quantitative Biology 2015-06-05 Yu Hu , James Trousdale , Kresimir Josic , Eric Shea-Brown

Community detection and hierarchy extraction are usually thought of as separate inference tasks on networks. Considering only one of the two when studying real-world data can be an oversimplification. In this work, we present a generative…

Social and Information Networks · Computer Science 2022-06-03 Laura Iacovissi , Caterina De Bacco

Topological features based on persistent homology capture high-order structural information so as to augment graph neural network methods. However, computing extended persistent homology summaries remains slow for large and dense graphs and…

Machine Learning · Computer Science 2022-11-16 Zuoyu Yan , Tengfei Ma , Liangcai Gao , Zhi Tang , Yusu Wang , Chao Chen

A wide variety of complex systems are characterized by interactions of different types involving varying numbers of units. Multiplex hypergraphs serve as a tool to describe such structures, capturing distinct types of higher-order…

Physics and Society · Physics 2024-09-10 Quintino Francesco Lotito , Alberto Montresor , Federico Battiston

One of the defining features of complex networks is the connectivity properties that we observe emerging from local interactions. Recently, hypergraphs have emerged as a versatile tool to model networks with non-dyadic, higher-order…

Physics and Society · Physics 2025-09-30 Berné L. Nortier , Simon Dobson , Federico Battiston

The network reconstruction task aims to estimate a complex system's structure from various data sources such as time series, snapshots, or interaction counts. Recent work has examined this problem in networks whose relationships involve…

Social and Information Networks · Computer Science 2023-12-05 Simon Lizotte , Jean-Gabriel Young , Antoine Allard

Higher order interactions are increasingly recognised as a fundamental aspect of complex systems ranging from the brain to social contact networks. Hypergraph as well as simplicial complexes capture the higher-order interactions of complex…

Physics and Society · Physics 2021-09-23 Hanlin Sun , Ginestra Bianconi

We propose a novel sequence prediction method for sequential data capturing node traversals in graphs. Our method builds on a statistical modelling framework that combines multiple higher-order network models into a single multi-order…

Machine Learning · Computer Science 2023-10-25 Christoph Gote , Giona Casiraghi , Frank Schweitzer , Ingo Scholtes

Temporal Graph Neural Networks (TGNNs) have gained growing attention for modeling and predicting structures in temporal graphs. However, existing TGNNs primarily focus on pairwise interactions while overlooking higher-order structures that…

Machine Learning · Computer Science 2025-05-22 Jingzhe Liu , Zhigang Hua , Yan Xie , Bingheng Li , Harry Shomer , Yu Song , Kaveh Hassani , Jiliang Tang

One of the most powerful techniques to study protein structures is to look for recurrent fragments (also called substructures or spatial motifs), then use them as patterns to characterize the proteins under study. An emergent trend consists…

Computational Engineering, Finance, and Science · Computer Science 2018-03-02 Wajdi Dhifli , Rabie Saidi , Engelbert Mephu Nguifo

The problem of calculating the frequencies of network motifs on three and four nodes in large networks is considered. Telecommunications networks, cell molecular networks are investigated. The sizes of the investigated networks are hundreds…

Social and Information Networks · Computer Science 2020-01-08 M. N. Yudina , V. N. Zadorozhnyi , E. B. Yudin

Individuals interact and cooperate in structured systems. Many studies represent this structure using static networks, where each link represents a permanent connection between two nodes. However, real interactions are generally not…

Physics and Society · Physics 2025-12-23 Xiaochen Wang , Lei Zhou , Alex McAvoy , Zhenglong Tian , Aming Li

A widely-used operation on graphs is local clustering, i.e., extracting a well-characterized community around a seed node without the need to process the whole graph. Recently local motif clustering has been proposed: it looks for a local…

Social and Information Networks · Computer Science 2022-05-13 Adil Chhabra , Marcelo Fonseca Faraj , Christian Schulz

The importance of higher-order relations is widely recognized in a large number of real-world systems. However, annotating them is a tedious and sometimes impossible task. Consequently, current approaches for data modelling either ignore…

Machine Learning · Computer Science 2025-06-06 Iulia Duta , Pietro Liò

We consider the problem of distilling efficient network topologies for collective communications. We provide an algorithmic framework for constructing direct-connect topologies optimized for the latency vs. bandwidth trade-off associated…

Networking and Internet Architecture · Computer Science 2025-02-04 Liangyu Zhao , Siddharth Pal , Tapan Chugh , Weiyang Wang , Jason Fantl , Prithwish Basu , Joud Khoury , Arvind Krishnamurthy

In real-world scenarios, large graphs represent relationships among entities in complex systems. Mining these large graphs often containing millions of nodes and edges helps uncover structural patterns and meaningful insights. Dividing a…

Social and Information Networks · Computer Science 2025-09-12 Shrabani Ghosh , Erik Saule