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We organized a workshop on the "Present and Future Frameworks of Theoretical Neuroscience", with the support of the National Science Foundation. The objective was to identify the challenges and strategies that this field will need to tackle…

Neurons and Cognition · Quantitative Biology 2020-04-06 Horacio G. Rotstein , Fidel Santamaria

In recent years, the field of neuroscience has gone through rapid experimental advances and a significant increase in the use of quantitative and computational methods. This growth has created a need for clearer analyses of the theory and…

The brain is a complex system comprising a myriad of interacting elements, posing significant challenges in understanding its structure, function, and dynamics. Network science has emerged as a powerful tool for studying such intricate…

Technological advances have dramatically expanded our ability to probe multi-neuronal dynamics and connectivity in the brain. However, our ability to extract a simple conceptual understanding from complex data is increasingly hampered by…

Neurons and Cognition · Quantitative Biology 2015-03-31 Peiran Gao , Surya Ganguli

From interacting cellular components to networks of neurons and neural systems, interconnected units comprise a fundamental organizing principle of the nervous system. Understanding how their patterns of connections and interactions give…

Neurons and Cognition · Quantitative Biology 2018-08-01 Danielle S. Bassett , Perry Zurn , Joshua I. Gold

This paper introduces several fundamental concepts in information theory from the perspective of their origins in engineering. Understanding such concepts is important in neuroscience for two reasons. Simply applying formulae from…

Information Theory · Computer Science 2016-03-29 Mark D. McDonnell , Shiro Ikeda , Jonathan H. Manton

Understanding how decision making changes across the lifespan is a central challenge for neuroscience, yet research on cognitive aging has remained largely disconnected from the theoretical and computational advances that now shape modern…

Neurons and Cognition · Quantitative Biology 2026-03-04 Michael B. Ryan , Letizia Ye , Anne K. Churchland

Finding general principles underlying brain function has been appealing to scientists. Indeed, in some branches of science like physics and chemistry (and to some degree biology) a general theory often can capture the essence of a wide…

Neurons and Cognition · Quantitative Biology 2023-12-22 Shervin Safavi

In recent years, neuroscience has made significant progress in building large-scale artificial neural network (ANN) models of brain activity and behavior. However, there is no consensus on the most efficient ways to collect data and design…

Human learning is a complex phenomenon that requires adaptive processes across a range of temporal and spacial scales. While our understanding of those processes at single scales has increased exponentially over the last few years, a…

Neurons and Cognition · Quantitative Biology 2016-09-08 Marcelo G. Mattar , Danielle S. Bassett

Neuroengineering is faced with unique challenges in repairing or replacing complex neural systems that are composed of many interacting parts. These interactions form intricate patterns over large spatiotemporal scales, and produce emergent…

Neurons and Cognition · Quantitative Biology 2016-12-26 Danielle S. Bassett , Ankit N. Khambhati , Scott T. Grafton

The brain is immensely complex, with diverse components and dynamic interactions building upon one another to orchestrate a wide range of functions and behaviors. Understanding patterns of these complex interactions and how they are…

Neurons and Cognition · Quantitative Biology 2024-08-06 Suman Kulkarni , Dani S. Bassett

Neural network models can now recognise images, understand text, translate languages, and play many human games at human or superhuman levels. These systems are highly abstracted, but are inspired by biological brains and use only…

Neurons and Cognition · Quantitative Biology 2019-03-06 Katherine R. Storrs , Nikolaus Kriegeskorte

Neural networks are a prevalent and effective machine learning component, and their application is leading to significant scientific progress in many domains. As the field of neural network systems is fast growing, it is important to…

Human-Computer Interaction · Computer Science 2022-11-22 Guy Clarke Marshall , André Freitas , Caroline Jay

The field of neuroscience is facing an unprecedented expanse in the volume and diversity of available data. Traditionally, network models have provided key insights into the structure and function of the brain. With the advent of big data…

Neurons and Cognition · Quantitative Biology 2018-02-14 Michael Vaiana , Sarah Muldoon

Deciphering the underpinnings of the dynamical processes leading to information transmission, processing, and storing in the brain is a crucial challenge in neuroscience. An inspiring but speculative theoretical idea is that such dynamics…

Statistical Mechanics · Physics 2023-07-21 Guillermo B. Morales , Serena Di Santo , Miguel A. Muñoz

Connectomics and network neuroscience offer quantitative scientific frameworks for modeling and analyzing networks of structurally and functionally interacting neurons, neuronal populations, and macroscopic brain areas. This shift in…

Neurons and Cognition · Quantitative Biology 2020-10-06 Richard Betzel

This review aims to contribute to the quest for artificial general intelligence by examining neuroscience and cognitive psychology methods for potential inspiration. Despite the impressive advancements achieved by deep learning models in…

Artificial Intelligence · Computer Science 2024-01-23 Florin Leon

In this paper, we make the case that a scientific theory of deep learning is emerging. By this we mean a theory which characterizes important properties and statistics of the training process, hidden representations, final weights, and…

Neural generative models can be used to learn complex probability distributions from data, to sample from them, and to produce probability density estimates. We propose a computational framework for developing neural generative models…

Machine Learning · Computer Science 2022-01-06 Alexander Ororbia , Daniel Kifer
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