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Related papers: Improving Mitosis Detection Via UNet-based Adversa…

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The proliferative activity of breast tumors, which is routinely estimated by counting of mitotic figures in hematoxylin and eosin stained histology sections, is considered to be one of the most important prognostic markers. However, mitosis…

For the MIDOG mitosis detection challenge, we created a cascade algorithm consisting of a Mask-RCNN detector, followed by a classification ensemble consisting of ResNet50 and DenseNet201 to refine detected mitotic candidates. The MIDOG…

Computer Vision and Pattern Recognition · Computer Science 2021-09-30 Gauthier Roy , Jules Dedieu , Capucine Bertrand , Alireza Moshayedi , Ali Mammadov , Stéphanie Petit , Saima Ben Hadj , Rutger H. J. Fick

Learning-based image dehazing methods are essential to assist autonomous systems in enhancing reliability. Due to the domain gap between synthetic and real domains, the internal information learned from synthesized images is usually…

Computer Vision and Pattern Recognition · Computer Science 2022-11-15 Wenqi Ren , Qiyu Sun , Chaoqiang Zhao , Yang Tang

Identification and counting of cells and mitotic figures is a standard task in diagnostic histopathology. Due to the large overall cell count on histological slides and the potential sparse prevalence of some relevant cell types or mitotic…

Computer Vision and Pattern Recognition · Computer Science 2017-09-08 Marc Aubreville , Maximilian Krappmann , Christof Bertram , Robert Klopfleisch , Andreas Maier

Accurate detection of mitosis plays a critical role in breast cancer histopathology. Manual detection and counting of mitosis is tedious and subject to considerable inter- and intra-reader variations. Multispectral imaging is a recent…

Computer Vision and Pattern Recognition · Computer Science 2013-04-16 H. Irshad , A. Gouaillard , L. Roux , D. Racoceanu

The variation in histologic staining between different medical centers is one of the most profound challenges in the field of computer-aided diagnosis. The appearance disparity of pathological whole slide images causes algorithms to become…

Image and Video Processing · Electrical Eng. & Systems 2024-04-05 Martin J. Hetz , Tabea-Clara Bucher , Titus J. Brinker

For histopathological tumor assessment, the count of mitotic figures per area is an important part of prognostication. Algorithmic approaches - such as for mitotic figure identification - have significantly improved in recent times,…

Computer Vision and Pattern Recognition · Computer Science 2020-02-20 Marc Aubreville , Christof A. Bertram , Samir Jabari , Christian Marzahl , Robert Klopfleisch , Andreas Maier

An organ segmentation method that can generalize to unseen contrasts and scanner settings can significantly reduce the need for retraining of deep learning models. Domain Generalization (DG) aims to achieve this goal. However, most DG…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Yanwu Xu , Shaoan Xie , Maxwell Reynolds , Matthew Ragoza , Mingming Gong , Kayhan Batmanghelich

This report details our submission to the Mitotic Domain Generalization (MIDOG) 2025 challenge, which addresses the critical task of mitotic figure detection in histopathology for cancer prognostication. Following the "Bitter…

Image and Video Processing · Electrical Eng. & Systems 2025-09-04 Zhuoyan Shen , Esther Bär , Maria Hawkins , Konstantin Bräutigam , Charles-Antoine Collins-Fekete

This work presents a mitosis detection method with only one vanilla Convolutional Neural Network (CNN). Our method consists of two steps: given an image, we first apply a CNN using a sliding window technique to extract patches that have…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Hongyan Gu , Mohammad Haeri , Shuo Ni , Christopher Kazu Williams , Neda Zarrin-Khameh , Shino Magaki , Xiang 'Anthony' Chen

Mitotic figure (MF) detection in histopathology images is challenging due to large variations in slide scanners, staining protocols, tissue types, and the presence of artifacts. This paper presents a collection of training techniques - a…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Christian Marzahl , Brian Napora

The problem of domain generalization is to take knowledge acquired from a number of related domains where training data is available, and to then successfully apply it to previously unseen domains. We propose a new feature learning…

Computer Vision and Pattern Recognition · Computer Science 2016-07-28 Muhammad Ghifary , W. Bastiaan Kleijn , Mengjie Zhang , David Balduzzi

This paper describes our contribution to the MIDOG 2022 challenge for detecting mitotic cells. One of the major problems to be addressed in the MIDOG 2022 challenge is the robustness under the natural variance that appears for real-life…

Computer Vision and Pattern Recognition · Computer Science 2023-09-14 Jonas Annuscheit , Christian Krumnow

Domain shift, the mismatch between training and testing data characteristics, causes significant degradation in the predictive performance in multi-source imaging scenarios. In medical imaging, the heterogeneity of population, scanners and…

Machine Learning · Computer Science 2021-12-21 Rongguang Wang , Pratik Chaudhari , Christos Davatzikos

Domain shift between medical images from multicentres is still an open question for the community, which degrades the generalization performance of deep learning models. Generative adversarial network (GAN), which synthesize plausible…

Image and Video Processing · Electrical Eng. & Systems 2020-07-31 Xinpeng Xie , Jiawei Chen , Yuexiang Li , Linlin Shen , Kai Ma , Yefeng Zheng

Recent advances in computer-aided diagnosis for histopathology have been largely driven by the use of deep learning models for automated image analysis. While these networks can perform on par with medical experts, their performance can be…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Frauke Wilm , Mathias Öttl , Marc Aubreville , Katharina Breininger

In this paper, we tackle the domain adaptive object detection problem, where the main challenge lies in significant domain gaps between source and target domains. Previous work seeks to plainly align image-level and instance-level shifts to…

Computer Vision and Pattern Recognition · Computer Science 2020-03-23 Chang-Dong Xu , Xing-Ran Zhao , Xin Jin , Xiu-Shen Wei

Deep learning models perform best when tested on target (test) data domains whose distribution is similar to the set of source (train) domains. However, model generalization can be hindered when there is significant difference in the…

Computer Vision and Pattern Recognition · Computer Science 2020-08-19 Pulkit Khandelwal , Paul Yushkevich

Generalization capabilities of learning-based medical image segmentation across domains are currently limited by the performance degradation caused by the domain shift, particularly for ultrasound (US) imaging. The quality of US images…

Image and Video Processing · Electrical Eng. & Systems 2024-02-07 Yuan Bi , Zhongliang Jiang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab

$\bf{Purpose:}$ The goal of this study was (i) to use artificial intelligence to automate the traditionally labor-intensive process of manual segmentation of tumor regions in pathology slides performed by a pathologist and (ii) to validate…