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Deep learning-based automated contouring and treatment planning has been proven to improve the efficiency and accuracy of radiotherapy. However, conventional radiotherapy treatment planning process has the automated contouring and treatment…

Medical Physics · Physics 2024-12-02 Sangwook Kim , Aly Khalifa , Thomas G. Purdie , Chris McIntosh

Purpose: Accurate prediction of beam delivery time (BDT) is essential for operational efficiency, 4D dose calculations, and advanced proton therapy techniques. Despite its importance, no machine-specific BDT model exists for Mevion systems.…

Medical Physics · Physics 2026-02-12 Giorgio Cartechini , Francesco Giuseppe Cordoni , Mirko Unipan , Ilaria Rinaldi

This paper introduces ITA-MDT, the Image-Timestep-Adaptive Masked Diffusion Transformer Framework for Image-Based Virtual Try-On (IVTON), designed to overcome the limitations of previous approaches by leveraging the Masked Diffusion…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Ji Woo Hong , Tri Ton , Trung X. Pham , Gwanhyeong Koo , Sunjae Yoon , Chang D. Yoo

The use of neural networks to directly predict three-dimensional dose distributions for automatic planning is becoming popular. However, the existing methods only use patient anatomy as input and assume consistent beam configuration for all…

Protoacoustic imaging showed great promise in providing real-time 3D dose verification of proton therapy. However, the limited acquisition angle in protoacoustic imaging induces severe artifacts, which significantly impairs its accuracy for…

Medical Physics · Physics 2023-08-14 Yankun Lang , Zhuoran Jiang , Leshan Sun , Liangzhong Xiang , Lei Ren

Dose-Volume Histogram (DVH) prediction is fundamental in radiation therapy that facilitate treatment planning, dose evaluation, plan comparison and etc. It helps to increase the ability to deliver precise and effective radiation treatments…

Machine Learning · Computer Science 2024-02-05 Zehao Dong , Yixin Chen , Tianyu Zhao

Applying diffusion models to image-to-image translation (I2I) has recently received increasing attention due to its practical applications. Previous attempts inject information from the source image into each denoising step for an iterative…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Mengfei Xia , Yu Zhou , Ran Yi , Yong-Jin Liu , Wenping Wang

Purpose: We present a framework for robust automated treatment planning using machine learning, comprising scenario-specific dose prediction and robust dose mimicking. Methods: The scenario dose prediction pipeline is divided into the…

Medical Physics · Physics 2022-10-12 Oskar Eriksson , Tianfang Zhang

This study investigates the applicability of 3D dose predictions from a model trained on one modality to a cross-modality automated planning workflow. Additionally, we explore the impact of integrating a multi-criteria optimizer on adapting…

Medical Physics · Physics 2024-02-26 Gregory Szalkowski , Xuanang Xu , Shiva Das , Pew-Thian Yap , Jun Lian

The development of a digital twin (DT) framework for fast online adaptive proton therapy planning in prostate stereotactic body radiation therapy (SBRT) with dominant intraprostatic lesion (DIL) boost represents a significant advancement in…

Radiotherapy treatment planning often relies on time-consuming, trial-and-error adjustments that heavily depend on the expertise of specialists, while existing deep learning methods face limitations in generalization, prediction accuracy,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Hui Xie , Haiqin Hu , Lijuan Ding , Qing Li , Yue Sun , Tao Tan

Dose volume histogram (DVH) metrics are widely accepted evaluation criteria in the clinic. However, incorporating these metrics into deep learning dose prediction models is challenging due to their non-convexity and non-differentiability.…

Computer Vision and Pattern Recognition · Computer Science 2022-09-07 Gourav Jhanwar , Navdeep Dahiya , Parmida Ghahremani , Masoud Zarepisheh , Saad Nadeem

Despite its success in image synthesis, we observe that diffusion probabilistic models (DPMs) often lack contextual reasoning ability to learn the relations among object parts in an image, leading to a slow learning process. To solve this…

Computer Vision and Pattern Recognition · Computer Science 2024-02-22 Shanghua Gao , Pan Zhou , Ming-Ming Cheng , Shuicheng Yan

The field of Radiation Oncology is uniquely positioned to benefit from the use of artificial intelligence to fully automate the creation of radiation treatment plans for cancer therapy. This time-consuming and specialized task combines…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Kuancheng Wang , Hai Siong Tan , Rafe Mcbeth

Diffusion tensor imaging (DTI) holds significant importance in clinical diagnosis and neuroscience research. However, conventional model-based fitting methods often suffer from sensitivity to noise, leading to decreased accuracy in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Jialong Li , Zhicheng Zhang , Yunwei Chen , Qiqi Lu , Ye Wu , Xiaoming Liu , QianJin Feng , Yanqiu Feng , Xinyuan Zhang

Background: Accurate and fast dose calculation is essential for optimizing carbon ion therapy. Existing machine learning (ML) models have been developed for other radiotherapy modalities. They use patient data with uniform CT imaging…

Novel radiotherapy techniques like synchrotron X-ray microbeam radiation therapy (MRT), require fast dose distribution predictions that are accurate at the sub-mm level, especially close to tissue/bone/air interfaces. Monte Carlo physics…

A novel dose calculation approach was designed based on the application of LSTM network that processes the 3D patient/phantom geometry as a sequence of 2D computed tomography input slices yielding a corresponding sequence of 2D slices that…

Medical Physics · Physics 2021-06-09 Ahmad Neishabouri , Niklas Wahl , Ulrich Köthe , Mark Bangert

Radiation therapy is the primary method used to treat cancer in the clinic. Its goal is to deliver a precise dose to the planning target volume (PTV) while protecting the surrounding organs at risk (OARs). However, the traditional workflow…

Image and Video Processing · Electrical Eng. & Systems 2024-04-10 Tara Gheshlaghi , Shahabedin Nabavi , Samire Shirzadikia , Mohsen Ebrahimi Moghaddam , Nima Rostampour

Model-assisted designs have garnered significant attention in recent years due to their high accuracy in identifying the maximum tolerated dose (MTD) and their operational simplicity. To identify the MTD, they employ estimated dose limiting…

Applications · Statistics 2025-08-19 Rentaro Wakayama , Tomotaka Momozaki , Shuji Ando