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Alzheimer's disease (AD) diagnosis is complex, requiring the integration of imaging and clinical data for accurate assessment. While deep learning has shown promise in brain MRI analysis, it often functions as a black box, limiting…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Yexiao He , Ziyao Wang , Yuning Zhang , Tingting Dan , Tianlong Chen , Guorong Wu , Ang Li

Automated methods for Alzheimer's disease (AD) classification have the potential for great clinical benefits and may provide insight for combating the disease. Machine learning, and more specifically deep neural networks, have been shown to…

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

Understanding the complex neural activity dynamics is crucial for the development of the field of neuroscience. Although current functional MRI classification approaches tend to be based on static functional connectivity or cannot capture…

Machine Learning · Computer Science 2025-08-20 Amirali Arbab , Zeinab Davarani , Mehran Safayani

Alzheimer's disease (AD) is a progressive brain disorder that causes memory and functional impairments. The advances in machine learning and publicly available medical datasets initiated multiple studies in AD diagnosis. In this work, we…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Aidana Massalimova , Huseyin Atakan Varol

Over the last years, increasing evidence has fuelled the hypothesis that Autism Spectrum Disorder (ASD) is a condition of altered brain functional connectivity. The great majority of these empirical studies rely on functional magnetic…

Neurons and Cognition · Quantitative Biology 2010-08-02 Pablo Barttfeld , Bruno Wicker , Sebastián Cukier , Silvana Navarta , Sergio Lew , Mariano Sigman

A plethora of deep learning models have been developed for the task of Alzheimer's disease classification from brain MRI scans. Many of these models report high performance, achieving three-class classification accuracy of up to 95%.…

Computer Vision and Pattern Recognition · Computer Science 2019-04-18 Ziqiang Guan , Ritesh Kumar , Yi Ren Fung , Yeahuay Wu , Madalina Fiterau

In open data sets of functional magnetic resonance imaging (fMRI), the heterogeneity of the data is typically attributed to a combination of factors, including differences in scanning procedures, the presence of confounding effects, and…

Machine Learning · Computer Science 2026-04-17 Xin Wen , Shijie Guo , Wenbo Ning , Rui Cao , Yan Niu , Bin Wan , Peng Wei , Xiaobo Liu , Jie Xiang

Speech patterns have been identified as potential diagnostic markers for neuropsychiatric conditions. However, most studies only compare a single clinical group to healthy controls, whereas clinical practice often requires differentiating…

Autism Spectrum Disorders (ASDs) are often associated with specific atypical postural or motor behaviors, of which Stereotypical Motor Movements (SMMs) have a specific visibility. While the identification and the quantification of SMM…

Neural and Evolutionary Computing · Computer Science 2016-06-08 Nastaran Mohammadian Rad , Andrea Bizzego , Seyed Mostafa Kia , Giuseppe Jurman , Paola Venuti , Cesare Furlanello

Neuroimaging datasets keep growing in size to address increasingly complex medical questions. However, even the largest datasets today alone are too small for training complex models or for finding genome wide associations. A solution is to…

Computer Vision and Pattern Recognition · Computer Science 2018-05-01 Christian Wachinger , Benjamin Gutierrez Becker , Anna Rieckmann

Attention Deficit Hyperactive Disorder (ADHD) is a common behavioral problem affecting children. In this work, we investigate the automatic classification of ADHD subjects using the resting state Functional Magnetic Resonance Imaging (fMRI)…

Neurons and Cognition · Quantitative Biology 2023-06-16 Soumyabrata Dey , Ravishankar Rao , Mubarak Shah

Introduction: Fetal resting-state functional magnetic resonance imaging (rs-fMRI) is a rapidly evolving field that provides valuable insight into brain development before birth. Accurate segmentation of the fetal brain from the surrounding…

Structural magnetic resonance imaging (sMRI) can identify subtle brain changes due to its high contrast for soft tissues and high spatial resolution. It has been widely used in diagnosing neurological brain diseases, such as Alzheimer…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Xin Zhang , Liangxiu Han , Lianghao Han , Haoming Chen , Darren Dancey , Daoqiang Zhang

We present two multimodal fusion-based deep learning models that consume ASR transcribed speech and acoustic data simultaneously to classify whether a speaker in a structured diagnostic task has Alzheimer's Disease and to what degree,…

Computation and Language · Computer Science 2021-07-01 Morteza Rohanian , Julian Hough , Matthew Purver

Magnetic Resonance Imaging (MRI) is a principal diagnostic approach used in the field of radiology to create images of the anatomical and physiological structure of patients. MRI is the prevalent medical imaging practice to find…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Yusuf Brima , Mossadek Hossain Kamal Tushar , Upama Kabir , Tariqul Islam

Autism Spectrum Disorder (ASD) is a pervasive developmental disorder of the central nervous system, primarily manifesting in childhood. It is characterized by atypical and repetitive behaviors. Currently, diagnostic methods mainly rely on…

Neurons and Cognition · Quantitative Biology 2025-03-21 Yiqian Luo , Qiurong Chen , Fali Li , Liang Yi , Peng Xu , Yangsong Zhang

In this article, we introduce a novel problem of audio-visual autism behavior recognition, which includes social behavior recognition, an essential aspect previously omitted in AI-assisted autism screening research. We define the task at…

Mobile digital therapeutics for autism spectrum disorder (ASD) often target emotion recognition and evocation, which is a challenge for children with ASD. While such mobile applications often use computer vision machine learning (ML) models…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Ali Kargarandehkordi , Matti Kaisti , Peter Washington

Theories for autism spectrum disorder (ASD) have been formulated at different levels: ranging from physiological observations to perceptual and behavioral descriptions. Understanding the physiological underpinnings of perceptual traits in…

Neurons and Cognition · Quantitative Biology 2021-12-03 Rodrigo Echeveste , Enzo Ferrante , Diego H. Milone , Inés Samengo