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Survival prediction is a crucial task associated with cancer diagnosis and treatment planning. This paper presents a novel approach to survival prediction by harnessing comprehensive information from CT and PET scans, along with associated…
This thesis focuses on representation learning for sequence data over time or space, aiming to improve downstream sequence prediction tasks by using the learned representations. Supervised learning has been the most dominant approach for…
Foundation models in healthcare have largely adopted self supervised pretraining objectives inherited from natural language processing and computer vision, emphasizing reconstruction and large scale representation learning prior to…
In recent years, deep learning methods have achieved great success in various fields due to their strong performance in practical applications. In this paper, we present a light-weight neural network for Parkinson's disease diagnostics, in…
Phonotactic constraints can be employed to distinguish languages by representing a speech utterance as a multinomial distribution or phone events. In the present study, we propose a new learning mechanism based on subspace-based…
Speech Sound Disorders (SSD) affect roughly five percent of children, yet speech-language pathologists face severe staffing shortages and unmanageable caseloads. We test a hierarchical approach to SSD classification on the granular…
The paper presents a novel deep learning approach, which extracts latent information from trained Deep Neural Networks (DNNs) and derives concise representations that are analyzed in an effective, unified way for prediction purposes. It is…
This thesis addresses challenges related to data and parameter efficiency in neural language models, with a focus on representation analysis and the introduction of new optimization techniques. The first part examines the properties and…
Depression commonly co-occurs with neurodegenerative disorders like Multiple Sclerosis (MS), yet the potential of speech-based Artificial Intelligence for detecting depression in such contexts remains unexplored. This study examines the…
Automatic classification of disordered speech can provide an objective tool for identifying the presence and severity of speech impairment. Classification approaches can also help identify hard-to-recognize speech samples to teach ASR…
Dysphonia is one of the early symptoms of Parkinson's disease (PD). Most existing methods use feature selection methods to find the optimal subset of voice features for all PD patients. Few have considered the heterogeneity between…
This paper addresses the problem of multi-channel multi-speech separation based on deep learning techniques. In the short time Fourier transform domain, we propose an end-to-end narrow-band network that directly takes as input the…
Recovering the masked speech frames is widely applied in speech representation learning. However, most of these models use random masking in the pre-training. In this work, we proposed two kinds of masking approaches: (1) speech-level…
Speech representation models based on the transformer architecture and trained by self-supervised learning have shown great promise for solving tasks such as speech and speaker recognition, keyword spotting, emotion detection, and more.…
Parkinson's disease (PD) is a neurodegenerative condition characterized by notable motor and non-motor manifestations. The assessment tool known as the Unified Parkinson's Disease Rating Scale (UPDRS) plays a crucial role in evaluating the…
A plethora of machine learning methods have been applied to imaging data, enabling the construction of clinically relevant imaging signatures of neurological and neuropsychiatric diseases. Oftentimes, such methods don't explicitly model the…
While current research has shown the importance of Multi-parametric MRI (mpMRI) in diagnosing prostate cancer (PCa), further investigation is needed for how to incorporate the specific structures of the mpMRI data, such as the regional…
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia, affecting memory, reasoning, communication, and daily functioning. Early diagnosis is particularly important, as timely intervention may…
Atypical Parkinsonian Disorders (APD), also known as Parkinson-plus syndrome, are a group of neurodegenerative diseases that include progressive supranuclear palsy (PSP) and multiple system atrophy (MSA). In the early stages, overlapping…
The electroencephalogram (EEG) is a powerful method to understand how the brain processes speech. Linear models have recently been replaced for this purpose with deep neural networks and yield promising results. In related EEG…