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We consider the edge-based compartmental models for infectious disease spread introduced in Part I. These models allow us to consider standard SIR diseases spreading in random populations. In this paper we show how to handle deviations of…

Populations and Evolution · Quantitative Biology 2015-09-03 Joel C. Miller , Erik M. Volz

Effective containment of spreading processes such as epidemics requires accurate knowledge of several key parameters that govern their dynamics. In this work, we first show that the problem of identifying the underlying parameters of…

Systems and Control · Electrical Eng. & Systems 2023-11-03 Chi Ho Leung , William E. Retnaraj , Ashish R. Hota , Philip E. Paré

As global living standards improve and medical technology advances, many infectious diseases have been effectively controlled. However, certain diseases, such as the recent COVID-19 pandemic, continue to pose significant threats to public…

Numerical Analysis · Mathematics 2025-02-24 Ayesha Baig , Li Zhouxin

In this work we performed a numerical study of an epidemic model that mimics the endemic state of whooping cough in the pre-vaccine era. We considered a stochastic SIR model on dynamical networks that involve local and global contacts among…

Physics and Society · Physics 2015-06-09 Martin Dottori , Gabriel Fabricius

Compartmental models like the Susceptible-Infected-Recovered (SIR)\cite{Kermack1927} and its extensions such as the Susceptible-Exposed-Infected-Recovered (SEIRS)\cite{Ottar2020,Ignazio2021,Grimm2021,Paoluzzi2021} are commonly used to model…

Populations and Evolution · Quantitative Biology 2025-07-14 Kasturi Banerjee , Subhankar Ray , Jayalakshmi Shamanna

We introduce an interacting particle system that models the spread of an epidemic in terms of heterogeneous diffusive dynamics, rather than exogenous contact and transmission rates at the population level as in classical compartmental…

Probability · Mathematics 2026-05-20 Eliana Fausti , Andreas Sojmark

HIV/AIDS spread depends upon complex patterns of interaction among various sub-sets emerging at population level. This added complexity makes it difficult to study and model AIDS and its dynamics. AIDS is therefore a natural candidate to be…

Multiagent Systems · Computer Science 2017-08-11 Amnah Siddiqa , Muaz A. Niazi

Risk management resulting from the actions and states of the different elements making up a operating room is a major concern during a surgical procedure. Agent-based simulation shows an interest through its interaction concepts,…

Artificial Intelligence · Computer Science 2020-07-23 Bruno Perez , Julien Henriet , Christophe Lang , Laurent Philippe

Mathematical models are formal and simplified representations of the knowledge related to a phenomenon. In classical epidemic models, a neglected aspect is the heterogeneity of disease transmission and progression linked to the viral load…

Physics and Society · Physics 2022-05-10 Rossella Della Marca , Nadia Loy , Andrea Tosin

Many advances in research regarding immuno-interactions with cancer were developed with the help of ordinary differential equation (ODE) models. These models, however, are not effectively capable of representing problems involving…

Computational Engineering, Finance, and Science · Computer Science 2013-06-03 Grazziela P. Figueredo , Peer-Olaf Siebers , Uwe Aickelin

A new dimension reduction method based on Gaussian finite mixtures is proposed as an extension to sliced inverse regression (SIR). The model-based SIR (MSIR) approach allows the main limitation of SIR to be overcome, i.e., failure in the…

Methodology · Statistics 2015-08-11 Luca Scrucca

Agent-based simulators provide granular representations of complex intelligent systems by directly modelling the interactions of the system's constituent agents. Their high-fidelity nature enables hyper-local policy evaluation and testing…

This paper presents a novel time-space SIR (Susceptible-Infected-Recovered) model for simulating infectious disease dynamics in two interconnected regions. The model is formulated as a coupled reaction-diffusion system with boundary…

Analysis of PDEs · Mathematics 2026-05-13 Omar Elamraoui , Jawad Salhi , Abderrahim Zafrar

The contact process is an emblematic model of a non-equilibrium system, containing a phase transition between inactive and active dynamical regimes. In the epidemiological context, the model is known as the susceptible-infected-susceptible…

Statistical Mechanics · Physics 2023-05-12 Wout Merbis , Clélia de Mulatier , Philippe Corboz

Mexico's National Institute of Geriatrics (INGER) is the national research center of reference for matters related to human aging. INGER scientists perform basic, clinical and demographic research which may imply different scientific…

The SIR model is the cornerstone model for mathematical epidemiology, explaining key epidemic features such as the second-order transition between disease-free and epidemic states, the initial exponential growth of outbreaks or the…

Populations and Evolution · Quantitative Biology 2026-03-20 Santiago Lamata-Otín , Alex Arenas , Jesús Gómez-Gardeñes , David Soriano-Paños

Since December 2019, A novel coronavirus (2019-nCoV) has been breaking out in China, which can cause respiratory diseases and severe pneumonia. Mathematical and empirical models relying on the epidemic situation scale for forecasting…

Populations and Evolution · Quantitative Biology 2021-01-05 Jingyuan Wang , Xin Lin , Yuxi Liu , Qilegeri , Kai Feng , Hui Lin

We consider the edge-based compartmental models for epidemic spread developed in Part I. We show conditions under which simpler models may be substituted for more detailed models, and in so doing we define a hierarchy of epidemic models. In…

Populations and Evolution · Quantitative Biology 2015-09-03 Joel C. Miller , Erik M. Volz

In this paper, we study the effectiveness of the modelling approach on the pandemic due to the spreading of the novel COVID-19 disease and develop a susceptible-infected-removed (SIR) model that provides a theoretical framework to…

Populations and Evolution · Quantitative Biology 2020-08-26 Ian Cooper , Argha Mondal , Chris G. Antonopoulos

We introduce a stochastic SIR-type partial differential equation model incorporating random diffusion, reinfection, vital dynamics, and a randomly varying transmission rate. For the associated random dynamical system, we prove the existence…