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Segmentation of focal (localized) brain pathologies such as brain tumors and brain lesions caused by multiple sclerosis and ischemic strokes are necessary for medical diagnosis, surgical planning and disease development as well as other…

Computer Vision and Pattern Recognition · Computer Science 2017-01-25 Mohammad Havaei , Nicolas Guizard , Hugo Larochelle , Pierre-Marc Jodoin

Speech language models align with human brain responses to natural language to an impressive degree. However, current models rely heavily on low-level speech features, indicating they lack brain-relevant semantics which limits their utility…

Computation and Language · Computer Science 2025-03-05 Omer Moussa , Dietrich Klakow , Mariya Toneva

In recent years, the rapid development of neuroimaging technology has been providing many powerful tools for cognitive neuroscience research. Among them, the functional magnetic resonance imaging (fMRI), which has high spatial resolution,…

Human-Computer Interaction · Computer Science 2018-08-20 Yang Wang , Dongrui Wu

Inference of brain functional connectivity networks from resting-state fMRI data is a key focus in neuroimaging. This paper introduces new Bayesian approaches for inferring a functional connectivity graph from multivariate resting-state…

In this paper, we provide an extensive overview of machine learning techniques applied to structural magnetic resonance imaging (MRI) data to obtain clinical classifiers. We specifically address practical problems commonly encountered in…

Quantitative Methods · Quantitative Biology 2018-08-20 José María Mateos-Pérez , Mahsa Dadar , María Lacalle-Aurioles , Yasser Iturria-Medina , Yashar Zeighami , Alan C. Evans

This article introduces an R package to perform statistical analysis for task-based fMRI data at both individual and group levels. The analysis to detect brain activation at the individual level is based on modeling the fMRI signal using…

Applications · Statistics 2021-11-03 Johnatan Cardona Jiménez

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu

Psychiatric disorders have historically been classified using symptom information alone. With the advent of new technologies that allowed researchers to investigate brain mechanisms more directly, interest in the mechanistic rationale…

Neurons and Cognition · Quantitative Biology 2020-07-02 Lucas Miranda , Riya Paul , Benno Pütz , Bertram Müller-Myhsok

Graphical models, used to express conditional dependence between random variables observed at various nodes, are used extensively in many fields such as genetics, neuroscience, and social network analysis. While most current statistical…

Methodology · Statistics 2022-10-25 Jiajing Niu , Boyoung Hur , John Absher , D. Andrew Brown

Finding an appropriate representation of dynamic activities in the brain is crucial for many downstream applications. Due to its highly dynamic nature, temporally averaged fMRI (functional magnetic resonance imaging) can only provide a…

Machine Learning · Computer Science 2022-08-18 Sikun Lin , Shuyun Tang , Scott Grafton , Ambuj Singh

Neuroimaging data, particularly from techniques like MRI or PET, offer rich but complex information about brain structure and activity. To manage this complexity, latent representation models - such as Autoencoders, Generative Adversarial…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 C. Vázquez-García , F. J. Martínez-Murcia , F. Segovia Román , Juan M. Górriz

Multimodal magnetic resonance imaging (MRI) constitutes the first line of investigation for clinicians in the care of brain tumors, providing crucial insights for surgery planning, treatment monitoring, and biomarker identification.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Lucas Robinet , Ahmad Berjaoui , Elizabeth Cohen-Jonathan Moyal

Diffusion models have recently emerged as powerful generative models in medical imaging. However, it remains a major challenge to combine these data-driven models with domain knowledge to guide brain imaging problems. In neuroimaging,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Ana Lawry Aguila , Dina Zemlyanker , You Cheng , Sudeshna Das , Daniel C. Alexander , Oula Puonti , Annabel Sorby-Adams , W. Taylor Kimberly , Juan Eugenio Iglesias

Backpropagation is the core learning mechanism underlying deep learning. However, whether and how this algorithm is implemented in the brain remains highly debated. In particular, while forward activations of pretrained models reliably map…

The accurate assessment of neuroimaging specificity is critical for advancing our understanding of brain disorders. Current methodologies often rely on frequentist approaches and limited cross-pathology comparisons, leading to potential…

Methodology · Statistics 2025-01-07 Tommaso Costa , Franco Cauda

Neuroimaging techniques including functional magnetic resonance imaging (fMRI) and electroencephalogram (EEG) have shown promise in detecting functional abnormalities in various brain disorders. However, existing studies often focus on a…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Xinxu Wei , Kanhao Zhao , Yong Jiao , Nancy B. Carlisle , Hua Xie , Gregory A. Fonzo , Yu Zhang

This is an empirical study to investigate the impact of scanner effects when using machine learning on multi-site neuroimaging data. We utilize structural T1-weighted brain MRI obtained from two different studies, Cam-CAN and UK Biobank.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Ben Glocker , Robert Robinson , Daniel C. Castro , Qi Dou , Ender Konukoglu

A reliable foundation model of functional neuroimages is critical to promote clinical applications where the performance of current AI models is significantly impeded by a limited sample size. To that end, tremendous efforts have been made…

Machine Learning · Computer Science 2025-10-23 Ziquan Wei , Tingting Dan , Guorong Wu

In this study, we propose a neural network approach to capture the functional connectivities among anatomic brain regions. The suggested approach estimates a set of brain networks, each of which represents the connectivity patterns of a…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Baran Baris Kivilcim , Itir Onal Ertugrul , Fatos T. Yarman Vural