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Related papers: MLT-LE: predicting drug-target binding affinity wi…

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A multi-task learning (MTL) system aims at solving multiple related tasks at the same time. With a fixed model capacity, the tasks would be conflicted with each other, and the system usually has to make a trade-off among learning all of…

Machine Learning · Computer Science 2021-02-16 Xi Lin , Zhiyuan Yang , Qingfu Zhang , Sam Kwong

The work for predicting drug and target affinity(DTA) is crucial for drug development and repurposing. In this work, we propose a novel method called GDGRU-DTA to predict the binding affinity between drugs and targets, which is based on…

Quantitative Methods · Quantitative Biology 2022-04-27 Lyu Zhijian , Jiang Shaohua , Liang Yigao , Gao Min

Prediction of molecular properties, including physico-chemical properties, is a challenging task in chemistry. Herein we present a new state-of-the-art multitask prediction method based on existing graph neural network models. We have used…

Machine Learning · Computer Science 2019-10-31 Fabio Capela , Vincent Nouchi , Ruud Van Deursen , Igor V. Tetko , Guillaume Godin

This paper targets the problem of multi-task dense prediction which aims to achieve simultaneous learning and inference on a bunch of multiple dense prediction tasks in a single framework. A core objective in design is how to effectively…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Siwei Yang , Hanrong Ye , Dan Xu

Self-supervised representation learning (SSL) on biomedical networks provides new opportunities for drug discovery. However, how to effectively combine multiple SSL models is still challenging and has been rarely explored. Therefore, we…

Machine Learning · Computer Science 2022-12-20 Xiaoqi Wang , Yingjie Cheng , Yaning Yang , Yue Yu , Fei Li , Shaoliang Peng

Drug-target binding affinity prediction is a fundamental task for drug discovery. It has been extensively explored in literature and promising results are reported. However, in this paper, we demonstrate that the results may be misleading…

Machine Learning · Computer Science 2025-04-15 Chenbin Zhang , Zhiqiang Hu , Chuchu Jiang , Wen Chen , Jie Xu , Shaoting Zhang

In recent years, Multi-task Learning (MTL) has yielded immense success in Recommender System (RS) applications. However, current MTL-based recommendation models tend to disregard the session-wise patterns of user-item interactions because…

Information Retrieval · Computer Science 2023-03-13 Ziru Liu , Jiejie Tian , Qingpeng Cai , Xiangyu Zhao , Jingtong Gao , Shuchang Liu , Dayou Chen , Tonghao He , Dong Zheng , Peng Jiang , Kun Gai

Protein-ligand binding is the process by which a small molecule (drug or inhibitor) attaches to a target protein. Binding affinity, which characterizes the strength of biomolecular interactions, is essential for tackling diverse challenges…

Multi-task learning (MTL) is an important subject in machine learning and artificial intelligence. Its applications to computer vision, signal processing, and speech recognition are ubiquitous. Although this subject has attracted…

Machine Learning · Computer Science 2021-03-02 Weizhu Qian , Bowei Chen , Yichao Zhang , Guanghui Wen , Franck Gechter

Multitask learning aims at solving a set of related tasks simultaneously, by exploiting the shared knowledge for improving the performance on individual tasks. Hence, an important aspect of multitask learning is to understand the…

Machine Learning · Computer Science 2019-10-22 Changjian Shui , Mahdieh Abbasi , Louis-Émile Robitaille , Boyu Wang , Christian Gagné

We study three general multi-task learning (MTL) approaches on 11 sequence tagging tasks. Our extensive empirical results show that in about 50% of the cases, jointly learning all 11 tasks improves upon either independent or pairwise…

Computation and Language · Computer Science 2018-08-14 Soravit Changpinyo , Hexiang Hu , Fei Sha

Sharing knowledge between tasks is vital for efficient learning in a multi-task setting. However, most research so far has focused on the easier case where knowledge transfer is not harmful, i.e., where knowledge from one task cannot…

Machine Learning · Computer Science 2019-07-08 Timo Bram , Gino Brunner , Oliver Richter , Roger Wattenhofer

The drug discovery stage is a vital aspect of the drug development process and forms part of the initial stages of the development pipeline. In recent times, machine learning-based methods are actively being used to model drug-target…

Machine Learning · Computer Science 2020-09-02 Brighter Agyemang , Wei-Ping Wu , Michael Yelpengne Kpiebaareh , Zhihua Lei , Ebenezer Nanor , Lei Chen

We introduce initial groundwork for estimating suicide risk and mental health in a deep learning framework. By modeling multiple conditions, the system learns to make predictions about suicide risk and mental health at a low false positive…

Computation and Language · Computer Science 2017-12-12 Adrian Benton , Margaret Mitchell , Dirk Hovy

Intelligent agents should have the ability to leverage knowledge from previously learned tasks in order to learn new ones quickly and efficiently. Meta-learning approaches have emerged as a popular solution to achieve this. However,…

Machine Learning · Computer Science 2023-02-17 Zhao Mandi , Pieter Abbeel , Stephen James

Deep learning models are known to function like the human brain. Due to their functional mechanism, they are frequently utilized to accomplish tasks that require human intelligence. Multi-target tracking (MTT) for video surveillance is one…

Computer Vision and Pattern Recognition · Computer Science 2021-11-01 Sanam Nisar Mangi

Multi-task learning (MTL) is a powerful approach in deep learning that leverages the information from multiple tasks during training to improve model performance. In medical imaging, MTL has shown great potential to solve various tasks.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Sangwook Kim , Thomas G. Purdie , Chris McIntosh

Multi-Task Learning is a learning paradigm that uses correlated tasks to improve performance generalization. A common way to learn multiple tasks is through the hard parameter sharing approach, in which a single architecture is used to…

Machine Learning · Computer Science 2022-04-15 Angelica Tiemi Mizuno Nakamura , Denis Fernando Wolf , Valdir Grassi

Multi-task learning (MTL) aims to improve the generalization of several related tasks by learning them jointly. As a comparison, in addition to the joint training scheme, modern meta-learning allows unseen tasks with limited labels during…

Machine Learning · Computer Science 2021-06-17 Haoxiang Wang , Han Zhao , Bo Li

A fundamental problem in multi-task learning (MTL) is identifying groups of tasks that should be learned together. Since training MTL models for all possible combinations of tasks is prohibitively expensive for large task sets, a crucial…

Machine Learning · Computer Science 2026-02-24 Afiya Ayman , Ayan Mukhopadhyay , Aron Laszka