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Advancement in digital pathology and artificial intelligence has enabled deep learning-based computer vision techniques for automated disease diagnosis and prognosis. However, WSIs present unique computational and algorithmic challenges.…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Yash Sharma , Lubaina Ehsan , Sana Syed , Donald E. Brown

Late-life depression (LLD) is a highly prevalent mood disorder occurring in older adults and is frequently accompanied by cognitive impairment (CI). Studies have shown that LLD may increase the risk of Alzheimer's disease (AD). However, the…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Lintao Zhang , Lihong Wang , Minhui Yu , Rong Wu , David C. Steffens , Guy G. Potter , Mingxia Liu

Digitized Histological diagnosis is in increasing demand. However, color variations due to various factors are imposing obstacles to the diagnosis process. The problem of stain color variations is a well-defined problem with many proposed…

Computer Vision and Pattern Recognition · Computer Science 2018-04-06 M Tarek Shaban , Christoph Baur , Nassir Navab , Shadi Albarqouni

Conventional multimodal recommender systems predominantly leverage Bayesian Personalized Ranking (BPR) optimization to learn item representations by amalgamating item identity (ID) embeddings with multimodal features. Nevertheless, our…

Information Retrieval · Computer Science 2025-05-09 Xin Zhou , Xiaoxiong Zhang , Dusit Niyato , Zhiqi Shen

Histopathology-based survival modelling has two major hurdles. Firstly, a well-performing survival model has minimal clinical application if it does not contribute to the stratification of a cancer patient cohort into different risk groups,…

Computer Vision and Pattern Recognition · Computer Science 2021-07-12 Hassan Muhammad , Chensu Xie , Carlie S. Sigel , Michael Doukas , Lindsay Alpert , William R. Jarnagin , Amber Simpson , Thomas J. Fuchs

Oculomics - the concept of predicting systemic diseases, such as cardiovascular disease and dementia, through retinal imaging - has advanced rapidly due to the data efficiency of transformer-based foundation models like RETFound.…

Machine Learning · Computer Science 2026-01-29 Hyunmin Kim , Yukun Zhou , Rahul A. Jonas , Lie Ju , Sunjin Hwang , Pearse A. Keane , Siegfried K. Wagner

The development of robust artificial intelligence models for histopathology diagnosis is severely constrained by the scarcity of expert-annotated lesion data, particularly for rare pathologies and underrepresented disease subtypes. While…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Mohamad Koohi-Moghadam , Mohammad-Ali Nikouei Mahani , Kyongtae Tyler Bae

Electronic health records (EHR) contain narrative notes that provide extensive details on the medical condition and management of patients. Natural language processing (NLP) of clinical notes can use observed frequencies of clinical terms…

Computation and Language · Computer Science 2023-07-04 Bryan Cai , Sihang Zeng , Yucong Lin , Zheng Yuan , Doudou Zhou , Lu Tian

The classification of medical images is a pivotal aspect of disease diagnosis, often enhanced by deep learning techniques. However, traditional approaches typically focus on unimodal medical image data, neglecting the integration of diverse…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Jun-En Ding , Chien-Chin Hsu , Chi-Hsiang Chu , Shuqiang Wang , Feng Liu

Multimodal molecular representation learning, which jointly models molecular graphs and their textual descriptions, enhances predictive accuracy and interpretability by enabling more robust and reliable predictions of drug toxicity,…

Machine Learning · Computer Science 2025-10-21 Yingxu Wang , Kunyu Zhang , Jiaxin Huang , Nan Yin , Siwei Liu , Eran Segal

Representation learning offers a conduit to elucidate distinctive features within the latent space and interpret the deep models. However, the randomness of lesion distribution and the complexity of low-quality factors in medical images…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Qingshan Hou , Shuai Cheng , Peng Cao , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane , Yih Chung Tham

One of the biggest challenges for applying machine learning to histopathology is weak supervision: whole-slide images have billions of pixels yet often only one global label. The state of the art therefore relies on strongly-supervised…

Image and Video Processing · Electrical Eng. & Systems 2020-12-08 Olivier Dehaene , Axel Camara , Olivier Moindrot , Axel de Lavergne , Pierre Courtiol

Annotating medical imaging datasets is costly, so fine-tuning (or transfer learning) is the most effective method for digital pathology vision applications such as disease classification and semantic segmentation. However, due to texture…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Tushar Kataria , Beatrice Knudsen , Shireen Elhabian

We present a novel LSTM cell architecture capable of learning both intra- and inter-perspective relationships available in visual sequences captured from multiple perspectives. Our architecture adopts a novel recurrent joint learning…

Computer Vision and Pattern Recognition · Computer Science 2021-05-07 Alireza Sepas-Moghaddam , Fernando Pereira , Paulo Lobato Correia , Ali Etemad

Robust generalization beyond training distributions remains a critical challenge for deep neural networks. This is especially pronounced in medical image analysis, where data is often scarce and covariate shifts arise from different…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Francesco Di Salvo , Sebastian Doerrich , Jonas Alle , Christian Ledig

Accurate diagnosis and treatment of complex diseases require integrating histological, molecular, and clinical data, yet in practice these modalities are often incomplete owing to tissue scarcity, assay cost, and workflow constraints.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Jinxi Xiang , Mingjie Li , Siyu Hou , Yijiang Chen , Xiangde Luo , Yuanfeng Ji , Xiang Zhou , Ehsan Adeli , Akshay Chaudhari , Curtis P. Langlotz , Kilian M. Pohl , Ruijiang Li

Recent advances in diffusion models have demonstrated impressive capability in generating high-quality images for simple prompts. However, when confronted with complex prompts involving multiple objects and hierarchical structures, existing…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Hongji Yang , Yucheng Zhou , Wencheng Han , Runzhou Tao , Zhongying Qiu , Jianfei Yang , Jianbing Shen

Appearance-based gaze estimation, aiming to predict accurate 3D gaze direction from a single facial image, has made promising progress in recent years. However, most methods suffer significant performance degradation in cross-domain…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Qida Tan , Hongyu Yang , Wenchao Du

Deep learning for histopathology has been successfully used for disease classification, image segmentation and more. However, combining image and text modalities using current state-of-the-art (SOTA) methods has been a challenge due to the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-18 Saurav Sengupta , Donald E. Brown

This work introduces SkinGenBench, a systematic biomedical imaging benchmark that investigates how preprocessing complexity interacts with generative model choice for synthetic dermoscopic image augmentation and downstream melanoma…

Image and Video Processing · Electrical Eng. & Systems 2026-04-03 N. A. Adarsh Pritam , Jeba Shiney O , Sanyam Jain
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