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Exponential-family random graph models (ERGMs) are probabilistic network models that are parametrized by sufficient statistics based on structural (i.e., graph-theoretic) properties. The ergm package for the R statistical computing system…

Social and Information Networks · Computer Science 2015-06-24 Omer Nebil Yaveroglu , Sean M. Fitzhugh , Maciej Kurant , Athina Markopoulou , Carter T. Butts , Natasa Przulj

The brain is a complex system comprising a myriad of interacting elements, posing significant challenges in understanding its structure, function, and dynamics. Network science has emerged as a powerful tool for studying such intricate…

A critical mystery in neuroscience lies in determining how anatomical structure impacts the complex functional dynamics of human thought. How does large-scale brain circuitry constrain states of neuronal activity and transitions between…

Neurons and Cognition · Quantitative Biology 2016-07-08 Shi Gu , Matthew Cieslak , Benjamin Baird , Sarah F. Muldoon , Scott T. Grafton , Fabio Pasqualetti , Danielle S. Bassett

Network theory provides novel concepts that promise an improved characterization of interacting dynamical systems. Within this framework, evolving networks can be considered as being composed of nodes, representing systems, and of…

Neurons and Cognition · Quantitative Biology 2014-08-26 Klaus Lehnertz , Gerrit Ansmann , Stephan Bialonski , Henning Dickten , Christian Geier , Stephan Porz

Nowadays, exponential random graphs (ERGs) are among the most widely-studied network models. Different analytical and numerical techniques for ERG have been developed that resulted in the well-established theory with true predictive power.…

Physics and Society · Physics 2014-04-08 Agata Fronczak

Understanding the human brain remains the Holy Grail in biomedical science, and arguably in all of the sciences. Our brains represent the most complex systems in the world (and some contend the universe) comprising nearly one hundred…

Quantitative Methods · Quantitative Biology 2016-02-03 Sean L. Simpson , Paul J. Laurienti

The principle of maximum entropy provides a useful method for inferring statistical mechanics models from observations in correlated systems, and is widely used in a variety of fields where accurate data are available. While the assumptions…

Neurons and Cognition · Quantitative Biology 2017-06-02 Ulisse Ferrari , Tomoyuki Obuchi , Thierry Mora

Analysis of the structure of biological networks often uses statistical tests to establish the over-representation of motifs, which are thought to be important building blocks of such networks, related to their biological functions.…

Molecular Networks · Quantitative Biology 2021-11-24 Alex Stivala , Alessandro Lomi

In the last 15 years, statistical physics has been a very successful framework to model complex networks. On the theoretical side, this approach has brought novel insights into a variety of physical phenomena, such as self-organisation,…

Networks are mathematical structures that are universally used to describe a large variety of complex systems such as the brain or the Internet. Characterizing the geometrical properties of these networks has become increasingly relevant…

Physics and Society · Physics 2015-05-26 Zhihao Wu , Giulia Menichetti , Christoph Rahmede , Ginestra Bianconi

Exponential-family random graph models (ERGMs) provide a principled and flexible way to model and simulate features common in social networks, such as propensities for homophily, mutuality, and friend-of-a-friend triad closure, through…

Methodology · Statistics 2012-08-01 Pavel N. Krivitsky

Understanding the complex hierarchical topology of functional brain networks is a key aspect of functional connectivity research. Such topics are obscured by the widespread use of sparse binary network models which are fundamentally…

Neurons and Cognition · Quantitative Biology 2016-11-17 Keith Smith , Javier Escudero

Mining human-brain networks to discover patterns that can be used to discriminate between healthy individuals and patients affected by some neurological disorder, is a fundamental task in neuroscience. Learning simple and interpretable…

Social and Information Networks · Computer Science 2020-06-11 Tommaso Lanciano , Francesco Bonchi , Aristides Gionis

Understanding the origins of complexity is a fundamental challenge with implications for biological and technological systems. Network theory emerges as a powerful tool to model complex systems. Networks are an intuitive framework to…

Disordered Systems and Neural Networks · Physics 2024-10-22 Blai Vidiella , Salva Duran-Nebreda , Sergi Valverde

In the brain, the structure of a network of neurons defines how these neurons implement the computations that underlie the mind and the behavior of animals and humans. Provided that we can describe the network of neurons as a graph, we can…

Computer Vision and Pattern Recognition · Computer Science 2019-07-03 Gustavo Borges Moreno e Mello , Vibeke Devold Valderhaug , Sidney Pontes-Filho , Evi Zouganeli , Ioanna Sandvig , Stefano Nichele

We analyze complexity in spatial network ensembles through the lens of graph entropy. Mathematically, we model a spatial network as a soft random geometric graph, i.e., a graph with two sources of randomness, namely nodes located randomly…

Physics and Society · Physics 2018-05-02 Justin P. Coon , Carl P. Dettmann , Orestis Georgiou

Currently we routinely develop a complex neuronal network to explain observed but often paradoxical phenomena based upon biological recordings. Here we present a general approach to demonstrate how to mathematically tackle such a complex…

Quantitative Methods · Quantitative Biology 2015-06-03 Yu Wu , Wenlian Lu , Wei Lin , Gareth Leng , Jianfeng Feng

The study of probabilistic models for the analysis of complex networks represents a flourishing research field. Among the former, Exponential Random Graphs (ERGs) have gained increasing attention over the years. So far, only linear ERGs…

Physics and Society · Physics 2026-02-10 Mattia Marzi , Francesca Giuffrida , Diego Garlaschelli , Tiziano Squartini

Exponential random graph models (ERGMs) are very flexible for modeling network formation but pose difficult estimation challenges due to their intractable normalizing constant. Existing methods, such as MCMC-MLE, rely on sequential…

Social and Information Networks · Computer Science 2025-02-05 Angelo Mele

How does the information flow between different brain regions during various stimuli? This is the question we aim to address by studying complex cognitive paradigms in terms of Information Theory. To assess creativity and the emergence of…

Neurons and Cognition · Quantitative Biology 2025-07-08 Ania Mesa-Rodríguez , Ernesto Estevez-Rams , Holger Kantz