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Autism Spectrum Disorder (ASD) is a pervasive developmental disorder of the central nervous system, primarily manifesting in childhood. It is characterized by atypical and repetitive behaviors. Currently, diagnostic methods mainly rely on…

Neurons and Cognition · Quantitative Biology 2025-03-21 Yiqian Luo , Qiurong Chen , Fali Li , Liang Yi , Peng Xu , Yangsong Zhang

The multifactorial etiology of autism spectrum disorder (ASD) suggests that its study would benefit greatly from multimodal approaches that combine data from widely varying platforms, e.g., neuroimaging, genetics, and clinical…

Quantitative Methods · Quantitative Biology 2023-08-11 Nicha C. Dvornek , Catherine Sullivan , James S. Duncan , Abha R. Gupta

Traditional regression models do not generalize well when learning from small and noisy datasets. Here we propose a novel metamodel structure to improve the regression result. The metamodel is composed of multiple classification base models…

Machine Learning · Computer Science 2021-05-07 Shiyu Wang , Nicha C. Dvornek

Slow Feature Analysis (SFA) extracts slowly varying features from a quickly varying input signal. It has been successfully applied to modeling the visual receptive fields of the cortical neurons. Sufficient experimental results in…

Computer Vision and Pattern Recognition · Computer Science 2019-07-17 Zhang Zhang , Dacheng Tao

We present a self-supervised learning method to learn audio and video representations. Prior work uses the natural correspondence between audio and video to define a standard cross-modal instance discrimination task, where a model is…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Pedro Morgado , Ishan Misra , Nuno Vasconcelos

Functional Magnetic Resonance Imaging (fMRI) provides useful insights into the brain function both during task or rest. Representing fMRI data using correlation matrices is found to be a reliable method of analyzing the inherent…

Machine Learning · Computer Science 2025-01-29 Yicheng Leng , Syed Muhammad Anwar , Islem Rekik , Sen He , Eung-Joo Lee

Children with Autism Spectrum Disorder (ASD) frequently exhibit comorbid anxiety, which contributes to impairment and requires treatment. Therefore, it is critical to investigate co-occurring autism and anxiety with functional imaging tools…

Neurons and Cognition · Quantitative Biology 2024-07-02 Peiyu Duan , Nicha C. Dvornek , Jiyao Wang , Jeffrey Eilbott , Yuexi Du , Denis G. Sukhodolsky , James S. Duncan

Autism Spectrum Disorder (ASD) lacks reliable biological markers, delaying early diagnosis. Using 159 salivary samples analyzed by ATR-FTIR spectroscopy, we developed GANet, a genetic algorithm-based network optimization framework…

Machine Learning · Computer Science 2025-09-22 Janayna M. Fernandes , Robinson Sabino-Silva , Murillo G. Carneiro

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition marked by disruptions in brain connectivity. Functional MRI (fMRI) offers a non-invasive window into large-scale neural dynamics by measuring…

Machine Learning · Computer Science 2025-08-20 Mohammad Izadi , Mehran Safayani

Learning disabilities like dysgraphia, dyslexia, dyspraxia, etc. interfere with academic achievements but have also long terms consequences beyond the academic time. It is widely admitted that between 5% to 10% of the world population is…

Other Computer Science · Computer Science 2020-05-14 Gilles Richard , Mathieu Serrurier

Autism spectrum disorder (ASD) is a developmental disorder characterized by significant social communication impairments and difficulties perceiving and presenting communication cues. Machine learning techniques have been broadly adopted to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Jicheng Li , Vuthea Chheang , Pinar Kullu , Eli Brignac , Zhang Guo , Kenneth E. Barner , Anjana Bhat , Roghayeh Leila Barmaki

Unsupervised aspect detection (UAD) aims at automatically extracting interpretable aspects and identifying aspect-specific segments (such as sentences) from online reviews. However, recent deep learning-based topic models, specifically…

Computation and Language · Computer Science 2021-01-01 Tian Shi , Liuqing Li , Ping Wang , Chandan K. Reddy

Alzheimer's disease (AD) is a common form of dementia that severely impacts patient health. As AD impairs the patient's language understanding and expression ability, the speech of AD patients can serve as an indicator of this disease. This…

Audio and Speech Processing · Electrical Eng. & Systems 2023-07-07 Hongmin Cai , Xiaoke Huang , Zhengliang Liu , Wenxiong Liao , Haixing Dai , Zihao Wu , Dajiang Zhu , Hui Ren , Quanzheng Li , Tianming Liu , Xiang Li

Autism Spectrum Disorder (ASD) is characterized by an altered phenotype in social interaction and communication. Additionally, autism typically manifests differently in females as opposed to males: a phenomenon that has likely led to…

Neurons and Cognition · Quantitative Biology 2024-05-08 Michelle McCleod , Sean Borneman , Evie Malaia

Alzheimers disease (AD) is a severe neurological brain disorder. It is not curable, but earlier detection can help improve symptoms in a great deal. The machine learning based approaches are popular and well motivated models for medical…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Lilia Lazli

Cognitive decline is a sign of Alzheimer's disease (AD), and there is evidence that tracking a person's eye movement, using eye tracking devices, can be used for the automatic identification of early signs of cognitive decline. However,…

Computation and Language · Computer Science 2019-10-02 Bahman Mirheidari , Yilin Pan , Traci Walker , Markus Reuber , Annalena Venneri , Daniel Blackburn , Heidi Christensen

Speech patterns have been identified as potential diagnostic markers for neuropsychiatric conditions. However, most studies only compare a single clinical group to healthy controls, whereas clinical practice often requires differentiating…

Action classification in still images has been a popular research topic in computer vision. Labelling large scale datasets for action classification requires tremendous manual work, which is hard to scale up. Besides, the action categories…

Computer Vision and Pattern Recognition · Computer Science 2016-09-09 Jiyang Gao , Ram Nevatia

Contrastive dimension reduction methods have been developed for case-control study data to identify variation that is enriched in the foreground (case) data X relative to the background (control) data Y. Here, we develop contrastive…

Methodology · Statistics 2024-01-09 Boyang Zhang , Sarah Nyquist , Andrew Jones , Barbara E. Engelhardt , Didong Li

Caregivers of individuals with autism spectrum disorder (ASD) often find the 77-item Autism Treatment Evaluation Checklist (ATEC) burdensome, limiting its use for routine monitoring. This study introduces a generalizable machine learning…

Applications · Statistics 2025-11-03 Audrey Dong , Claire Xu , Samuel R. Guo , Kevin Yang , Xue-Jun Kong