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Deep Learning neural networks are pervasive, but traditional computer architectures are reaching the limits of being able to efficiently execute them for the large workloads of today. They are limited by the von Neumann bottleneck: the high…

Emerging Technologies · Computer Science 2022-06-22 Wilfried Haensch , Anand Raghunathan , Kaushik Roy , Bhaswar Chakrabarti , Charudatta M. Phatak , Cheng Wang , Supratik Guha

Most normative models in computational neuroscience describe the task of learning as the optimisation of a cost function with respect to a set of parameters. However, learning as optimisation fails to account for a time varying environment…

Neurons and Cognition · Quantitative Biology 2020-08-10 Jannes Jegminat , Jean-Pascal Pfister

While deep learning has led to remarkable advances across diverse applications, it struggles in domains where the data distribution changes over the course of learning. In stark contrast, biological neural networks continually adapt to…

Machine Learning · Computer Science 2017-06-14 Friedemann Zenke , Ben Poole , Surya Ganguli

The advent of comprehensive synaptic wiring diagrams of large neural circuits has created the field of connectomics and given rise to a number of open research questions. One such question is whether it is possible to reconstruct the…

Neurons and Cognition · Quantitative Biology 2023-02-20 Sebastian Goldt , Florent Krzakala , Lenka Zdeborová , Nicolas Brunel

To learn useful dynamics on long time scales, neurons must use plasticity rules that account for long-term, circuit-wide effects of synaptic changes. In other words, neural circuits must solve a credit assignment problem to appropriately…

Neurons and Cognition · Quantitative Biology 2019-05-30 Owen Marschall , Kyunghyun Cho , Cristina Savin

Self-sustained, elevated neuronal activity persisting on time scales of ten seconds or longer is thought to be vital for aspects of working memory, including brain representations of real space. Continuous-attractor neural networks, one of…

Neurons and Cognition · Quantitative Biology 2020-08-19 Joseph L. Natale , H. George E. Hentschel , Ilya Nemenman

Memory networks are neural networks with an explicit memory component that can be both read and written to by the network. The memory is often addressed in a soft way using a softmax function, making end-to-end training with backpropagation…

Machine Learning · Statistics 2016-05-25 Sarath Chandar , Sungjin Ahn , Hugo Larochelle , Pascal Vincent , Gerald Tesauro , Yoshua Bengio

We consider a fully-connected network of leaky integrate-and-fire neurons with spike-timing-dependent plasticity. The plasticity is controlled by a parameter representing the expected weight of a synapse between neurons that are firing…

Neurons and Cognition · Quantitative Biology 2011-09-23 Chun-Chung Chen , David Jasnow

Physical reservoir computing is a computational framework that implements spatiotemporal information processing directly within physical systems. By exciting nonlinear dynamical systems and creating linear models from their state, we can…

Machine Learning · Computer Science 2025-07-08 Jake Love , Jeroen Mulkers , Robin Msiska , George Bourianoff , Jonathan Leliaert , Karin Everschor-Sitte

The spiking activity of principal cells in mammalian hippocampus encodes an internalized neuronal representation of the ambient space---a cognitive map. Once learned, such a map enables the animal to navigate a given environment for a long…

Neurons and Cognition · Quantitative Biology 2017-10-10 Andrey Babichev , Dmitriy Morozov , Yuri Dabaghian

There is increasing realization in neuroscience that information is represented in the brain, e.g., neocortex, hippocampus, in the form sparse distributed codes (SDCs), a kind of cell assembly. Two essential questions are: a) how are such…

Machine Learning · Computer Science 2020-10-22 Rod Rinkus

The brain is a nonlinear and highly Recurrent Neural Network (RNN). This RNN is surprisingly plastic and supports our astonishing ability to learn and execute complex tasks. However, learning is incredibly complicated due to the brain's…

Neural and Evolutionary Computing · Computer Science 2023-03-14 Mohammad Modiri

A hallmark of biological intelligence is neural reuse,the ability to preserve past learning and repurpose it for new tasks and changing environments. Photonic neural hardware offers high-bandwidth, low-latency computation, but current…

This paper describes a framework for modeling the interface between perception and memory on the algorithmic level of analysis. It is consistent with phenomena associated with many different brain regions. These include view-dependence (and…

Neural and Evolutionary Computing · Computer Science 2015-12-29 Joel Z. Leibo , Julien Cornebise , Sergio Gómez , Demis Hassabis

Synaptic plasticity is widely accepted to be the mechanism behind learning in the brain's neural networks. A central question is how synapses, with access to only local information about the network, can still organize collectively and…

Neural and Evolutionary Computing · Computer Science 2019-12-06 Dina Obeid , Hugo Ramambason , Cengiz Pehlevan

In this paper, we investigated the neural spikes synchronisation in a neural network with synaptic plasticity and external perturbation. In the simulations the neural dynamics is described by the Hodgkin Huxley model considering chemical…

A biomolecular system representing the first realization of associative memory based on enzymatic reactions in vitro has been designed. The system demonstrated "training" and "forgetting" features characteristic of memory in biological…

Molecular Networks · Quantitative Biology 2013-11-05 Kevin MacVittie , Jan Halamek , Vladimir Privman , Evgeny Katz

A number of studies have concluded that dreaming is mostly caused by randomly arriving internal signals because "dream contents are random impulses", and argued that dream sleep is unlikely to play an important part in our intellectual…

Neurons and Cognition · Quantitative Biology 2026-02-05 Qi Zhang

The quest for energy-efficient, scalable neuromorphic computing has elevated compute-in-memory (CIM) architectures to the forefront of hardware innovation. While memristive memories have been extensively explored for synaptic implementation…

Materials Science · Physics 2025-08-20 Kapil Bhardwaj , Ella Paasio , Sayani Majumdar

Codifying memories is one of the fundamental problems of modern Neuroscience. The functional mechanisms behind this phenomenon remain largely unknown. Experimental evidence suggests that some of the memory functions are performed by…

Neurons and Cognition · Quantitative Biology 2022-05-17 Ivan Y. Tyukin , Alexander N. Gorban , Carlos Calvo , Julia Makarova , Valeri A. Makarov
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