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Ontologies in the biomedical domain are numerous, highly specialized and very expensive to develop. Thus, a crucial prerequisite for ontology adoption and reuse is effective support for exploring and finding existing ontologies. Towards…

Social and Information Networks · Computer Science 2022-05-17 Simon Walk , Lisette Espín-Noboa , Denis Helic , Markus Strohmaier , Mark Musen

Biomedical ontologies, which comprehensively define concepts and relations for biomedical entities, are crucial for structuring and formalizing domain-specific information representations. Biomedical code mapping identifies similarity or…

Information Retrieval · Computer Science 2025-02-27 Hui Feng , Yuntzu Yin , Emiliano Reynares , Jay Nanavati

The healthcare industry is moving towards a patient-centric paradigm that requires advanced methods for managing and representing patient data. This paper presents a Patient Journey Ontology (PJO), a framework that aims to capture the…

Databases · Computer Science 2025-06-25 Hassan S. Al Khatib , Subash Neupane , Sudip Mittal , Shahram Rahimi , Nina Marhamati , Sean Bozorgzad

Many platforms for benchmarking optimization algorithms offer users the possibility of sharing their experimental data with the purpose of promoting reproducible and reusable research. However, different platforms use different data models…

Neural and Evolutionary Computing · Computer Science 2021-04-27 Ana Kostovska , Diederick Vermetten , Carola Doerr , Sašo Džeroski , Panče Panov , Tome Eftimov

Poor data quality has become a pervasive issue due to the increasing complexity and size of modern datasets. Constraint based data cleaning techniques rely on integrity constraints as a benchmark to identify and correct errors. Data values…

Databases · Computer Science 2017-05-25 Sridevi Baskaran , Alexander Keller , Fei Chiang , Golab Lukasz , Jaroslaw Szlichta

Personalized oncology aims to tailor treatment strategies to the unique molecular and clinical profiles of individual patients, moving beyond the traditional paradigm of treating the disease not the patient. Achieving this vision requires…

Electronic health records (EHRs) contain vast amounts of complex data, but harmonizing and processing this information remains a challenging and costly task requiring significant clinical expertise. While large language models (LLMs) have…

Computation and Language · Computer Science 2024-07-02 João Matos , Jack Gallifant , Jian Pei , A. Ian Wong

Ontology alignment is the task of identifying semantically equivalent entities from two given ontologies. Different ontologies have different representations of the same entity, resulting in a need to de-duplicate entities when merging…

Computation and Language · Computer Science 2018-06-22 Lucy Lu Wang , Chandra Bhagavatula , Mark Neumann , Kyle Lo , Chris Wilhelm , Waleed Ammar

There is a growing need to semantically process and integrate clinical data from different sources for clinical research. This paper presents an approach to integrate EHRs from heterogeneous resources and generate integrated data in…

Ontology-based approaches for predicting gene-disease associations include the more classical semantic similarity methods and more recently knowledge graph embeddings. While semantic similarity is typically restricted to hierarchical…

Machine Learning · Computer Science 2021-06-01 Susana Nunes , Rita T. Sousa , Catia Pesquita

Computational phenotyping has emerged as a practical solution to the incomplete collection of data on gender in electronic health records (EHRs). This approach relies on algorithms to infer a patient's gender using the available data in…

Traditional object detection models in medical imaging operate within a closed-set paradigm, limiting their ability to detect objects of novel labels. Open-vocabulary object detection (OVOD) addresses this limitation but remains…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Tooba Tehreem Sheikh , Jean Lahoud , Rao Muhammad Anwer , Fahad Shahbaz Khan , Salman Khan , Hisham Cholakkal

This paper studies the role that ontologies can play in establishing conceptual data models during the process of information systems development. A mapping algorithm has been proposed and embedded in a special purpose Transformation-Engine…

Software Engineering · Computer Science 2007-05-23 Haya El-Ghalayini , Mohammed Odeh , Richard McClatchey

HONeYBEE (Harmonized ONcologY Biomedical Embedding Encoder) is an open-source framework that integrates multimodal biomedical data for oncology applications. It processes clinical data (structured and unstructured), whole-slide images,…

Machine Learning · Computer Science 2025-08-28 Aakash Tripathi , Asim Waqas , Matthew B. Schabath , Yasin Yilmaz , Ghulam Rasool

With the rapid advancements in cancer research, the information that is useful for characterizing disease, staging tumors, and creating treatment and survivorship plans has been changing at a pace that creates challenges when physicians try…

In recent years, following FAIR and open data principles, the number of available big data including biomedical data has been increased exponentially. In order to extract knowledge, these data should be curated, integrated, and semantically…

Databases · Computer Science 2018-11-06 Samaneh Jozashoori , Tatiana Novikova , Maria-Esther Vidal

High-throughput omics profiling advancements have greatly enhanced cancer patient stratification. However, incomplete data in multi-omics integration presents a significant challenge, as traditional methods like sample exclusion or…

Genomics · Quantitative Biology 2024-01-17 Shihao Ma , Andy G. X. Zeng , Benjamin Haibe-Kains , Anna Goldenberg , John E Dick , Bo Wang

Social determinants of health are societal factors, such as where a person was born, grew up, works, lives, etc, along with socioeconomic and community factors that affect individual health. Social Determinants of Health are correlated with…

Information Retrieval · Computer Science 2022-11-16 Navya Martin Kollapally , Yan Chen , Julia Xu , James Geller

There is a large number of online documents data sources available nowadays. The lack of structure and the differences between formats are the main difficulties to automatically extract information from them, which also has a negative…

SNOMED CT is a biomedical ontology with a hierarchical representation, modelling terminological concepts at a large scale. Knowledge retrieval in SNOMED CT is critical for its application but often proves challenging due to linguistic…

Computation and Language · Computer Science 2026-04-21 Jonathon Dilworth , Hui Yang , Jiaoyan Chen , Yongsheng Gao , Ernesto Jimenez-Ruiz