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This study investigates the application of general human motion encoders trained on large-scale human motion datasets for analyzing gait patterns in PD patients. Although these models have learned a wealth of human biomechanical knowledge,…
Current alignment-based methods for classification in geometric morphometrics do not generally address the classification of new individuals that were not part of the study sample. However, in the context of infant and child nutritional…
Health-related quality of life (Hr-QoL) scales provide crucial information on neurodegenerative disease progression, help improving patient care, and constitute a meaningful endpoint for therapeutic research. However, Hr-QoL progression is…
Knee osteoarthritis (OA) is the most common musculoskeletal disease without a cure, and current treatment options are limited to symptomatic relief. Prediction of OA progression is a very challenging and timely issue, and it could, if…
PPG based heart rate (HR) monitoring has recently attracted much attention with the advent of wearable devices such as smart watches and smart bands. However, due to severe motion artifacts (MA) caused by wristband stumbles, PPG based HR…
Currently used clinical assessments for physical function do not objectively quantify daily activities in routine living. Wearable activity monitors enable objective measurement of routine daily activities, but do not map to clinically…
Clinical methods that assess gait in Parkinson's Disease (PD) are mostly qualitative. Quantitative methods necessitate costly instrumentation or cumbersome wearable devices, which limits their usability. Only few of these methods can…
Automated quality assessment of structural brain MRI is an important prerequisite for reliable neuroimaging analysis, but yet remains challenging due to motion artifacts and poor generalization across acquisition sites. Existing approaches…
Statistical shape modeling (SSM) directly from 3D medical images is an underutilized tool for detecting pathology, diagnosing disease, and conducting population-level morphology analysis. Deep learning frameworks have increased the…
We introduce a novel state-space model (SSM)-based framework for skeleton-based human action recognition, with an anatomically-guided architecture that improves state-of-the-art performance in both clinical diagnostics and general action…
The health monitoring of chronic diseases is very important for people with movement disorders because of their limited mobility and long duration of chronic diseases. Machine learning-based processing of data collected from the human with…
Image quality of PET reconstructions is degraded by subject motion occurring during the acquisition. MR-based motion correction approaches have been studied for PET/MR scanners and have been successful at capturing regular motion patterns,…
B-mode ultrasound is commonly used to image musculoskeletal tissues, but one major bottleneck is data interpretation, and analyses of muscle thickness, pennation angle and fascicle length are often still performed manually. In this study we…
In this article, we analyze the morphometry of hippocampus in subjects with very mild dementia of Alzheimer's type (DAT) and nondemented controls and how it changes over a two-year period. Morphometric differences with respect to a template…
Surgeons' technical skill directly impacts patient outcomes. To date, the angular motion of the instruments has been largely overlooked in objective skill evaluation. To fill this gap, we have developed metrics for surgical skill evaluation…
Skeletal bone age assessment is a common clinical practice to diagnose endocrine and metabolic disorders in child development. In this paper, we describe a fully automated deep learning approach to the problem of bone age assessment using…
Parkinson's disease (PD) is a progressive neurodegenerative condition characterized by the death of dopaminergic neurons, leading to various movement disorder symptoms. Early diagnosis of PD is crucial to prevent adverse effects, yet…
The growth index $\gamma$ is a powerful trigger for detecting deviations from $\Lambda$CDM. However, its value is often determined by considering an asymptotic constant value that works for all redshift, or else following a chosen…
Parkinson's Disease (PD) is associated with gait movement disorders, such as bradykinesia, stiffness, tremors and postural instability, caused by progressive dopamine deficiency. Today, some approaches have implemented learning…
The Health State Function theory is applied to find a quantitative estimate of the Human Development Stages by defining and calculating the specific age groups and subgroups. Early and late adolescence stages, first, second and third stages…