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Clinical assessments for neuromuscular disorders, such as Spinal Muscular Atrophy (SMA) and Duchenne Muscular Dystrophy (DMD), continue to rely on subjective measures to monitor treatment response and disease progression. We introduce a…

Motion-related artifacts are inevitable in Magnetic Resonance Imaging (MRI) and can bias automated neuroanatomical metrics such as cortical thickness. These biases can interfere with statistical analysis which is a major concern as motion…

Image and Video Processing · Electrical Eng. & Systems 2025-06-11 Charles Bricout , Samira Ebrahimi Kahou , Sylvain Bouix

Differences in gait patterns of children with Duchenne muscular dystrophy (DMD) and typically-developing (TD) peers are visible to the eye, but quantifications of those differences outside of the gait laboratory have been elusive. In this…

Neuromuscular diseases (NMDs) cause a significant burden for both healthcare systems and society. They can lead to severe progressive muscle weakness, muscle degeneration, contracture, deformity and progressive disability. The NMDs…

Image and Video Processing · Electrical Eng. & Systems 2022-01-28 Maja Schlereth , Daniel Stromer , Katharina Breininger , Alexandra Wagner , Lina Tan , Andreas Maier , Ferdinand Knieling

Parkinson's disease (PD) is a progressive neurological disorder primarily affecting motor function resulting in tremor at rest, rigidity, bradykinesia, and postural instability. The physical severity of PD impairments can be quantified…

Computer Vision and Pattern Recognition · Computer Science 2020-07-20 Mandy Lu , Kathleen Poston , Adolf Pfefferbaum , Edith V. Sullivan , Li Fei-Fei , Kilian M. Pohl , Juan Carlos Niebles , Ehsan Adeli

Neurological disorders, including stroke, spinal cord injuries, multiple sclerosis, and Parkinson's disease, generally lead to diminished upper extremity (UE) function, impacting individuals' independence and quality of life. Traditional…

Signal Processing · Electrical Eng. & Systems 2024-08-02 Tommaso Proietti , Andrea Bandini

Perinatal stroke (PS) is a serious condition that, if undetected and thus untreated, often leads to life-long disability, in particular Cerebral Palsy (CP). In clinical settings, Prechtl's General Movement Assessment (GMA) can be used to…

Human-Computer Interaction · Computer Science 2019-02-22 Yan Gao , Yang Long , Yu Guan , Anna Basu , Jessica Baggaley , Thomas Ploetz

Accelerometry has been extensively studied as an objective means of measuring upper limb function in patients post-stroke. The objective of this paper is to determine whether the accelerometry-derived measurements frequently used in more…

Machine Learning · Computer Science 2023-11-09 Mackenzie Wallich , Kenneth Lai , Svetlana Yanushkevich

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition associated with difficulties with social interactions, communication, and restricted or repetitive behaviors. To characterize ASD, investigators often use functional…

Methodology · Statistics 2026-05-12 Jialu Ran , Sarah Shultz , Benjamin B. Risk , David Benkeser

Strokes are a leading cause of disability, with many experiencing difficulty in recovering arm movement, particularly hand function and grasping ability. There is currently no objective measure of movement quality, and without it,…

Quantitative Methods · Quantitative Biology 2023-05-24 Khadija F. Zaidi , Michelle Harris-Love

Multivariate regression models for age estimation are a powerful tool for assessing abnormal brain morphology associated to neuropathology. Age prediction models are built on cohorts of healthy subjects and are built to reflect normal aging…

Computer Vision and Pattern Recognition · Computer Science 2018-04-05 Benjamin Gutierrez Becker , Tassilo Klein , Christian Wachinger

For the task of mobility analysis of 3D shapes, we propose joint analysis for simultaneous motion part segmentation and motion attribute estimation, taking a single 3D model as input. The problem is significantly different from those…

Computer Vision and Pattern Recognition · Computer Science 2019-03-13 Xiaogang Wang , Bin Zhou , Yahao Shi , Xiaowu Chen , Qinping Zhao , Kai Xu

Marker-based Optical Motion Capture (OMC) paired with biomechanical modeling is currently considered the most precise and accurate method for measuring human movement kinematics. However, combining differentiable biomechanical modeling with…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Tim Unger , Arash Sal Moslehian , J. D. Peiffer , Johann Ullrich , Roger Gassert , Olivier Lambercy , R. James Cotton , Chris Awai Easthope

Background: Minute-level accelerometer data capture rich diurnal physical activity (PA) patterns, but conventional summary metrics obscures clinically meaningful changes accumulated across a day. Building on Riemannian framework, we…

Upper extremity motor impairment affects about 80\% of persons after strokes. For stroke rehabilitation, upper limb kinematic assessments have increasingly been used as primary or secondary outcome measures. Studying the upper extremity…

Quantitative Methods · Quantitative Biology 2023-05-18 Khadija F. Zaidi , Michelle Harris-Love

Assessing the quality of movements for post-stroke patients during the rehabilitation phase is vital given that there is no standard stroke rehabilitation plan for all the patients. In fact, it depends basically on the patient's functional…

Signal Processing · Electrical Eng. & Systems 2023-01-02 Asma Bensalah , Alicia Fornés , Cristina Carmona-Duarte , Josep Lladós

Infants' neurological development is heavily influenced by their motor skills. Evaluating a baby's movements is key to understanding possible risks of developmental disorders in their growth. Previous research in psychology has shown that…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Bruno Tafur , Marwa Mahmoud , Staci Weiss

Smartphone applications designed to track human motion in combination with wearable sensors, e.g., during physical exercising, raised huge attention recently. Commonly, they provide quantitative services, such as personalized training…

Machine Learning · Computer Science 2017-11-23 Andre Ebert , Michael Till Beck , Andy Mattausch , Lenz Belzner , Claudia Linnhoff Popien

Hyperkinetic movement disorders (HMDs) in children, including dystonia (abnormal twisting) and chorea (irregular, random movements), pose significant diagnostic challenges due to overlapping clinical features. The prevalence of dystonia…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Nandika Ramamurthy , Dr Daniel Lumsden , Dr Rachel Sparks

Physical activity (PA) is significantly associated with many health outcomes. The wide usage of wearable accelerometer-based activity trackers in recent years has provided a unique opportunity for in-depth research on PA and its relations…

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