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Bilestones are solid masses found in the gallbladder or biliary tract, which block the normal bile flow and eventually result in severe life-threatening complications. Studies have shown that bilestone formation may be related to bile flow…

Precise segmentation of bladder walls and tumor regions is an essential step towards non-invasive identification of tumor stage and grade, which is critical for treatment decision and prognosis of patients with bladder cancer (BC). However,…

Computer Vision and Pattern Recognition · Computer Science 2019-03-06 Jose Dolz , Xiaopan Xu , Jerome Rony , Jing Yuan , Yang Liu , Eric Granger , Christian Desrosiers , Xi Zhang , Ismail Ben Ayed , Hongbing Lu

Primary tumors have a high likelihood of developing metastases in the liver and early detection of these metastases is crucial for patient outcome. We propose a method based on convolutional neural networks (CNN) to detect liver metastases.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-16 Mariëlle J. A. Jansen , Hugo J. Kuijf , Maarten Niekel , Wouter B. Veldhuis , Frank J. Wessels , Max A. Viergever , Josien P. W. Pluim

Surgical assessment of liver cancer patients requires identification of the vessel trees from medical images. Specifically, the venous trees - the portal (perfusing) and the hepatic (draining) trees are important for understanding the liver…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 Yassine Machta , Omar Ali , Kevin Hakkakian , Ana Vlasceanu , Amaury Facque , Nicolas Golse , Irene Vignon-Clementel

Bile, the central metabolic product of the liver, is secreted by hepatocytes into bile canaliculi (BC), tubular subcellular structures of 0.5-2 $\mu$m diameter which are formed by the apical membranes of juxtaposed hepatocytes. BC…

Tissues and Organs · Quantitative Biology 2020-12-24 Lutz Brusch , Yannis Kalaidzidis , Kirstin Meyer , Ivo F. Sbalzarini , Marino Zerial

This study introduces a new method of visualizing complex tree structured objects. The usefulness of this method is illustrated in the context of detecting unexpected features in a data set of very large trees. The major contribution is a…

Applications · Statistics 2012-02-14 Burcu Aydin , Gabor Pataki , Haonan Wang , Alim Ladha , Elizabeth Bullitt , J. S. Marron

Medical imaging is the most important tool for detecting complications in the inner body of medicine. Nowadays, with the development of image processing technology as well as changing the size of photos to higher resolution images in the…

Image and Video Processing · Electrical Eng. & Systems 2022-07-19 Mahmoudreza Moghimhanjani , Ali Taghavirashidizadeh

This research aims to develop an efficient system for screening of diabetic retinopathy. Diabetic retinopathy is the major cause of blindness. Severity of diabetic retinopathy is recognized by some features, such as blood vessel area,…

Image and Video Processing · Electrical Eng. & Systems 2020-01-08 Faisal Ghaffar , Sarwar Khan , Bunyarit Uyyanonvara , Chanjira Sinthanayothin , Hirohiko Kaneko

Stereotactic Body Radiation Therapy (SBRT) can be a precise, minimally invasive treatment method for liver cancer and liver metastases. However, the effectiveness of SBRT relies on the accurate delivery of the dose to the tumor while…

Medical Physics · Physics 2024-11-26 Sugandima Weragoda , Ping Xia , Kevin Stephans , Neil Woody , Michael Martens , Robert Brown , Bingqi Guo

Background: The aim of this study was to develop and evaluate a deep learning-based automated segmentation method for hepatic anatomy (i.e., parenchyma, tumors, portal vein, hepatic vein and biliary tree) from the hepatobiliary phase of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-21 Karin A. Olthof , Matteo Fusagli , Bianca Güttner , Tiziano Natali , Bram Westerink , Stefanie Speidel , Theo J. M. Ruers , Koert F. D. Kuhlmann , Andrey Zhylka

Tubular structure segmentation in medical images, e.g., segmenting vessels in CT scans, serves as a vital step in the use of computers to aid in screening early stages of related diseases. But automatic tubular structure segmentation in CT…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yan Wang , Xu Wei , Fengze Liu , Jieneng Chen , Yuyin Zhou , Wei Shen , Elliot K. Fishman , Alan L. Yuille

Liver cirrhosis represents the end stage of chronic liver disease, characterized by extensive fibrosis and nodular regeneration that significantly increases mortality risk. While magnetic resonance imaging (MRI) offers a non-invasive…

Various structures in human physiology follow a treelike morphology, which often expresses complexity at very fine scales. Examples of such structures are intrathoracic airways, retinal blood vessels, and hepatic blood vessels. Large…

Image and Video Processing · Electrical Eng. & Systems 2022-09-23 Hao Li , Zeyu Tang , Yang Nan , Guang Yang

The liver is one of the most critical metabolic organs in vertebrates due to its vital functions in the human body, such as detoxification of the blood from waste products and medications. Liver diseases due to liver tumors are one of the…

Image and Video Processing · Electrical Eng. & Systems 2022-08-30 Khaled Humady , Yasmeen Al-Saeed , Nabila Eladawi , Ahmed Elgarayhi , Mohammed Elmogy , Mohammed Sallah

Cilia are hairlike structures protruding from nearly every cell in the body. Diseases known as ciliopathies, where cilia function is disrupted, can result in a wide spectrum of disorders. However, most techniques for assessing ciliary…

Machine Learning · Computer Science 2018-03-21 Charles Lu , M. Marx , M. Zahid , C. W. Lo , C. Chennubhotla , S. P. Quinn

The reliable segmentation of retinal vasculature can provide the means to diagnose and monitor the progression of a variety of diseases affecting the blood vessel network, including diabetes and hypertension. We leverage the power of…

Image and Video Processing · Electrical Eng. & Systems 2019-07-23 Ali Hatamizadeh , Hamid Hosseini , Zhengyuan Liu , Steven D. Schwartz , Demetri Terzopoulos

The aortic vessel tree is composed of the aorta and its branching arteries, and plays a key role in supplying the whole body with blood. Aortic diseases, like aneurysms or dissections, can lead to an aortic rupture, whose treatment with…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Yuan Jin , Antonio Pepe , Jianning Li , Christina Gsaxner , Fen-hua Zhao , Kelsey L. Pomykala , Jens Kleesiek , Alejandro F. Frangi , Jan Egger

Advances in computing technology have allowed researchers across many fields of endeavor to collect and maintain vast amounts of observational statistical data such as clinical data,biological patient data,data regarding access of web…

Computer Vision and Pattern Recognition · Computer Science 2014-12-10 Narkhede Sachin , Deven Shah , Vaishali Khairnar , Sujata Kadu

Pancreatic duct dilation indicates a high risk of various pancreatic diseases. Segmentation of dilated pancreatic ducts on computed tomography (CT) images shows the potential to assist the early diagnosis, surgical planning and prognosis.…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Liwen Zou , Zhenghua Cai , Yudong Qiu , Luying Gui , Liang Mao , Xiaoping Yang

The human spine is a complex structure composed of 33 vertebrae. It holds the body and is important for leading a healthy life. The spine is vulnerable to age-related degenerations that can be identified through magnetic resonance imaging…

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