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The trajectory of an individual's recovery after traumatic brain injury (TBI) is heterogeneous, with complete recovery in some cases but persistent disability in others. We hypothesized that changes in structural brain network abnormalities…

Prognoses of Traumatic Brain Injury (TBI) outcomes are neither easily nor accurately determined from clinical indicators. This is due in part to the heterogeneity of damage inflicted to the brain, ultimately resulting in diverse and complex…

Infants with autism were recently found to have prolonged Auditory Brainstem Response (ABR); however, at older ages, findings are contradictory. We compared ABR differences between participants with autism and controls with respect to age…

Neurons and Cognition · Quantitative Biology 2017-10-11 Oren Miron , Andrew L. Beam , Isaac S. Kohane

Veterans with mild traumatic brain injury (mTBI) have reported auditory and visual dysfunction that persists beyond the acute incident. The etiology behind these symptoms is difficult to characterize with current clinical imaging. These…

Image and Video Processing · Electrical Eng. & Systems 2020-06-24 Cailey I. Kerley , Kurt G. Schilling , Justin Blaber , Beth Miller , Allen Newton , Adam W. Anderson , Bennett A. Landman , Tonia S. Rex

The accurate prognosis for traumatic brain injury (TBI) patients is difficult yet essential to inform therapy, patient management, and long-term after-care. Patient characteristics such as age, motor and pupil responsiveness, hypoxia and…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Margherita Rosnati , Eyal Soreq , Miguel Monteiro , Lucia Li , Neil S. N. Graham , Karl Zimmerman , Carlotta Rossi , Greta Carrara , Guido Bertolini , David J. Sharp , Ben Glocker

Human behavior training in improvisational theater has shown extensive behavioral and health benefits. Improved empathy measures in medical students, improved behavior outcome in patients with autism and a reduced recidivism rate are among…

Other Quantitative Biology · Quantitative Biology 2023-12-05 Vikram Jakkamsetti , Clinton Broyles , Frank Buttafarro , Clint R. Myers , Sophia Kwong Myers

Purpose: This study evaluated whether articulatory kinematics, inferred by Articulatory Phonology speech inversion neural networks, aligned with perceptual ratings of /r/ and /s/ in the speech of children with speech sound disorders.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-07-03 Nina R. Benway , Saba Tabatabaee , Dongliang Wang , Benjamin Munson , Jonathan L. Preston , Carol Espy-Wilson

Traumatic Brain Injury (TBI) presents a broad spectrum of clinical presentations and outcomes due to its inherent heterogeneity, leading to diverse recovery trajectories and varied therapeutic responses. While many studies have delved into…

Machine Learning · Computer Science 2024-08-22 Hamid Ghaderi , Brandon Foreman , Chandan K. Reddy , Vignesh Subbian

Background: Glial fibrillary acidic protein (GFAP) is a biomarker for intracerebral hemorrhage and traumatic brain injury, but its link to acute speech disruption is untested. Speech anomalies often emerge early after injury, enabling rapid…

Neurons and Cognition · Quantitative Biology 2025-08-15 Shamaley Aravinthan , Bin Hu

Traumatic brain injury (TBI) is intrinsically heterogeneous, and typical clinical outcome measures like the Glasgow Coma Scale complicate this diversity. The large variability in severity and patient outcomes render it difficult to link…

A key desiderata for inclusive and accessible speech recognition technology is ensuring its robust performance to children's speech. Notably, this includes the rapidly advancing neural network based end-to-end speech recognition systems.…

Audio and Speech Processing · Electrical Eng. & Systems 2021-02-22 Prashanth Gurunath Shivakumar , Shrikanth Narayanan

Post-traumatic epilepsy (PTE) is a life-long complication of traumatic brain injury (TBI) and is a major public health problem that has an estimated incidence that ranges from 2%-50%, depending on the severity of the TBI. Currently, the…

Quantitative Methods · Quantitative Biology 2020-11-17 Md Navid Akbar , Marianna La Rocca , Rachael Garner , Dominique Duncan , Deniz Erdoğmuş

Traumatic brain injury (TBI) can cause cognitive, communication, and psychological challenges that profoundly limit independence in everyday life. Conversational Agents (CAs) can provide individuals with TBI with cognitive and communication…

Mild traumatic brain injury (mTBI) is a growing public health problem with an estimated incidence of one million people annually in US. Neurocognitive tests are used to both assess the patient condition and to monitor the patient progress.…

Computer Vision and Pattern Recognition · Computer Science 2018-02-16 Shervin Minaee , Siyun Wang , Yao Wang , Sohae Chung , Xiuyuan Wang , Els Fieremans , Steven Flanagan , Joseph Rath , Yvonne W. Lui

Oral narrative skills are strong predictors of later literacy development. This study examines the features of oral narratives from children who were identified by experts as requiring intervention. Using simple machine learning methods, we…

Computation and Language · Computer Science 2025-07-21 Emma Sharratt , Annelien Smith , Retief Louw , Daleen Klop , Febe de Wet , Herman Kamper

Cerebrovascular dynamics and pathomechanisms that evolve in the minutes and hours following traumatic vascular injury in the brain remain largely unknown. We investigated the pathophysiology evolution within the first three hours after…

The diffused nature of mild traumatic brain injury (mTBI) impacts brain white-matter pathways with potentially long-term consequences, even after initial symptoms have resolved. To understand post-mTBI recovery in adolescents, longitudinal…

Neurons and Cognition · Quantitative Biology 2019-12-13 Ai Wern Chung , Rebekah Mannix , Henry A. Feldman , P. Ellen Grant , Kiho Im

This paper presents a macroscopic approach to automatic detection of speech sound disorder (SSD) in child speech. Typically, SSD is manifested by persistent articulation and phonological errors on specific phonemes in the language. The…

Audio and Speech Processing · Electrical Eng. & Systems 2022-06-30 Si-Ioi Ng , Cymie Wing-Yee Ng , Jiarui Wang , Tan Lee

Naturalistic recordings capture audio in real-world environments where participants behave naturally without interference from researchers or experimental protocols. Naturalistic long-form recordings extend this concept by capturing…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-24 Jialu Li , Marvin Lavechin , Xulin Fan , Nancy L. McElwain , Alejandrina Cristia , Paola Garcia-Perera , Mark Hasegawa-Johnson

Automatic inference of important paralinguistic information such as age from speech is an important area of research with numerous spoken language technology based applications. Speaker age estimation has applications in enabling…

Audio and Speech Processing · Electrical Eng. & Systems 2024-06-19 Prashanth Gurunath Shivakumar , Somer Bishop , Catherine Lord , Shrikanth Narayanan
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