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Objective: Assessing the appropriateness of diagnostic referrals is critical for improving healthcare efficiency and reducing unnecessary procedures. However, this task becomes challenging when referral reasons are recorded only as free…

Computation and Language · Computer Science 2025-09-05 Vittorio Torri , Annamaria Bottelli , Michele Ercolanoni , Olivia Leoni , Francesca Ieva

Clinical trials usually target average treatment effects, but treatment decisions are made for individuals. This tension motivates a common criticism of evidence-based medicine: a treatment that is beneficial on average may be inappropriate…

Applications · Statistics 2026-05-29 Zach Shahn , Mats Stensrud

Describing and analysing learner behaviour using sequential data and analysis is becoming more and more popular in Learning Analytics. Nevertheless, we found a variety of definitions of learning sequences, as well as choices regarding data…

Computers and Society · Computer Science 2023-12-13 Manuel Valle Torre , Catharine Oertel , Marcus Specht

Depression is a widespread mental disorder that affects millions worldwide. While automated depression assessment shows promise, most studies rely on limited or non-clinically validated data, and often prioritize complex model design over…

Computation and Language · Computer Science 2025-08-07 Zhuang Chen , Guanqun Bi , Wen Zhang , Jiawei Hu , Aoyun Wang , Xiyao Xiao , Kun Feng , Minlie Huang

While incorporating LLMs into systems offers significant benefits in critical application areas such as healthcare, new security challenges emerge due to the potential cyber kill chain cycles that combine adversarial model, prompt injection…

Cryptography and Security · Computer Science 2026-03-05 Neha Nagaraja , Hayretdin Bahsi

Medication adherence is a problem of widespread concern in clinical care. Poor adherence is a particular problem for patients with chronic diseases requiring long-term medication because poor adherence can result in less successful…

Methodology · Statistics 2021-04-26 Kristen B. Hunter , Mark E. Glickman , Luis F. Campos

Mental health disorders are rising worldwide. However, the availability of trained clinicians has not scaled proportionally, leaving many people without adequate or timely support. To bridge this gap, recent studies have shown the promise…

Computation and Language · Computer Science 2025-08-19 Aishik Mandal , Prottay Kumar Adhikary , Hiba Arnaout , Iryna Gurevych , Tanmoy Chakraborty

Clinical practice in psychiatry is burdened with the increased demand for healthcare services and the scarce resources available. New paradigms of health data powered with machine learning techniques could open the possibility to improve…

Artificial Intelligence · Computer Science 2023-06-08 Juan Sebastian Canas , Francisco Gomez , Omar Costilla-Reyes

In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

Quantitative Methods · Quantitative Biology 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu

While NLP typically treats documents as independent and unordered samples, in longitudinal studies, this assumption rarely holds: documents are nested within authors and ordered in time, forming person-indexed, time-ordered…

Assessing care quality and performance is essential to improve healthcare processes and population health management. However, due to bad system design and lack of access to required data, this assessment is often delayed or not done at…

Computers and Society · Computer Science 2017-11-28 Douglas Teodoro , Nils Rotgans , Lucas Oliveira , Lilian Correia

In modern dynamic constantly developing society, more and more people suffer from chronic and serious diseases and doctors and patients need special and sophisticated medical and health support. Accordingly, prominent health stakeholders…

Computers and Society · Computer Science 2022-08-10 Mirjana Ivanovic , Serge Autexier , Miltiadis Kokkonidis

This paper presents a reproducible and process-aware pipeline for predictive monitoring of clinical pathways. The approach integrates data lifting, temporal reconstruction, event log construction, prefix-based representations, and…

Machine Learning · Computer Science 2026-05-13 Pasquale Ardimento , Mario Luca Bernardi , Marta Cimitile , Samuele Latorre

A dynamic treatment regime is a sequence of decision rules in which each decision rule recommends treatment based on features of patient medical history such as past treatments and outcomes. Existing methods for estimating optimal dynamic…

Methodology · Statistics 2015-05-22 Kristin A. Linn , Eric B. Laber , Leonard A. Stefanski

Personalized predictive medicine necessitates the modeling of patient illness and care processes, which inherently have long-term temporal dependencies. Healthcare observations, recorded in electronic medical records, are episodic and…

Machine Learning · Statistics 2017-04-12 Trang Pham , Truyen Tran , Dinh Phung , Svetha Venkatesh

When faced with complex and uncertain medical conditions (e.g., cancer, mental health conditions, recovery from substance dependency), millions of patients seek online peer support. In this study, we leverage content analysis of online…

Human-Computer Interaction · Computer Science 2025-03-31 Madhusudan Basak , Omar Sharif , Jessica Hulsey , Elizabeth C. Saunders , Daisy J. Goodman , Luke J. Archibald , Sarah M. Preum

Clinical event sequences consist of hundreds of clinical events that represent records of patient care in time. Developing accurate predictive models of such sequences is of a great importance for supporting a variety of models for…

Machine Learning · Computer Science 2023-08-23 Jeong Min Lee , Milos Hauskrecht

Understanding treatment effect heterogeneity has become increasingly important in many fields. In this paper we study distributions and quantiles of individual treatment effects to provide a more comprehensive and robust understanding of…

Methodology · Statistics 2026-03-31 Zhe Chen , Xinran Li

Generative models can produce synthetic patient records for analytical tasks when real data is unavailable or limited. However, current methods struggle with adhering to domain-specific knowledge and removing invalid data. We present…

Machine Learning · Computer Science 2023-12-22 Brandon Theodorou , Shrusti Jain , Cao Xiao , Jimeng Sun

Health information technologies are transforming how mental healthcare is paid for through value-based care programs, which tie payment to data quantifying care outcomes. But, it is unclear what outcomes data these technologies should…

Human-Computer Interaction · Computer Science 2025-02-05 Daniel A. Adler , Yuewen Yang , Thalia Viranda , Anna R. Van Meter , Emma Elizabeth McGinty , Tanzeem Choudhury
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