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The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

Computation and Language · Computer Science 2023-12-08 Angeela Acharya , Sulabh Shrestha , Anyi Chen , Joseph Conte , Sanja Avramovic , Siddhartha Sikdar , Antonios Anastasopoulos , Sanmay Das

Accuracy and interpretability are two dominant features of successful predictive models. Typically, a choice must be made in favor of complex black box models such as recurrent neural networks (RNN) for accuracy versus less accurate but…

Machine Learning · Computer Science 2017-02-28 Edward Choi , Mohammad Taha Bahadori , Joshua A. Kulas , Andy Schuetz , Walter F. Stewart , Jimeng Sun

Hospital readmission prediction is considered an essential approach to decreasing readmission rates, which is a key factor in assessing the quality and efficacy of a healthcare system. Previous studies have extensively utilized three…

Machine Learning · Computer Science 2023-11-15 Yan Miao , Lequan Yu

The integration of multimodal Electronic Health Records (EHR) data has significantly improved clinical predictive capabilities. Leveraging clinical notes and multivariate time-series EHR, existing models often lack the medical context…

Artificial Intelligence · Computer Science 2024-02-13 Yinghao Zhu , Changyu Ren , Shiyun Xie , Shukai Liu , Hangyuan Ji , Zixiang Wang , Tao Sun , Long He , Zhoujun Li , Xi Zhu , Chengwei Pan

With the wide application of electronic health records (EHR) in healthcare facilities, health event prediction with deep learning has gained more and more attention. A common feature of EHR data used for deep-learning-based predictions is…

Machine Learning · Computer Science 2021-12-17 Chang Lu , Tian Han , Yue Ning

The adoption of digital systems in healthcare has resulted in the accumulation of vast electronic health records (EHRs), offering valuable data for machine learning methods to predict patient health outcomes. However, single-visit records…

Machine Learning · Computer Science 2024-11-19 Eric Yang , Pengfei Hu , Xiaoxue Han , Yue Ning

Electronic Health Records (EHR) have revolutionized healthcare by digitizing patient data, improving accessibility, and streamlining clinical workflows. However, extracting meaningful insights from these complex and multimodal datasets…

Artificial Intelligence · Computer Science 2025-10-27 Naama Kashani , Mira Cohen , Uri Shaham

Electronic Health Record (EHR) has become an essential tool in the healthcare ecosystem, providing authorized clinicians with patients' health-related information for better treatment. While most developed countries are taking advantage of…

Electronic health records (EHR) offer unprecedented opportunities for in-depth clinical phenotyping and prediction of clinical outcomes. Combining multiple data sources is crucial to generate a complete picture of disease prevalence,…

Computation and Language · Computer Science 2022-12-01 Anna Munoz-Farre , Harry Rose , Sera Aylin Cakiroglu

Large language models (LLMs) offer a generalizable approach for modeling patient trajectories, but suffer from the long and noisy nature of electronic health records (EHR) data in temporal reasoning. To address these challenges, we…

Artificial Intelligence · Computer Science 2026-05-18 Sihang Zeng , Yujuan Fu , Sitong Zhou , Zixuan Yu , Lucas Jing Liu , Jun Wen , Matthew Thompson , Ruth Etzioni , Meliha Yetisgen

Electronic Health Records (EHRs), comprising diverse clinical data such as diagnoses, medications, and laboratory results, hold great promise for translational research. EHR-derived data have advanced disease prevention, improved clinical…

Machine Learning · Statistics 2025-09-09 Yinjie Wang , Doudou Zhou , Yue Liu , Junwei Lu , Tianxi Cai

Multimodal electronic health record (EHR) data are widely used in clinical applications. Conventional methods usually assume that each sample (patient) is associated with the unified observed modalities, and all modalities are available for…

Machine Learning · Computer Science 2022-11-01 Chaohe Zhang , Xu Chu , Liantao Ma , Yinghao Zhu , Yasha Wang , Jiangtao Wang , Junfeng Zhao

In this paper we study the problem of predicting clinical diagnoses from textual Electronic Health Records (EHR) data. We show the importance of this problem in medical community and present comprehensive historical review of the problem…

Computation and Language · Computer Science 2020-09-29 Pavel Blinov , Manvel Avetisian , Vladimir Kokh , Dmitry Umerenkov , Alexander Tuzhilin

Recent deep learning research based on Transformer model architectures has demonstrated state-of-the-art performance across a variety of domains and tasks, mostly within the computer vision and natural language processing domains. While…

Machine Learning · Computer Science 2021-11-11 Benjamin Shickel , Patrick J. Tighe , Azra Bihorac , Parisa Rashidi

In recent years, healthcare professionals are increasingly emphasizing on personalized and evidence-based patient care through the exploration of prognostic pathways. To study this, structured clinical variables from Electronic Health…

Computation and Language · Computer Science 2025-09-16 Sudeshna Jana , Tirthankar Dasgupta , Lipika Dey

Electronic health records (EHRs) linked with familial relationship data offer a unique opportunity to investigate the genetic architecture of complex phenotypes at scale. However, existing heritability and coheritability estimation methods…

Methodology · Statistics 2025-11-12 Yinjun Zhao , Nicholas Tatonetti , Yuanjia Wang

With the proliferation of Electronic Health Records (EHRs), a critical challenge in building predictive models is determining the optimal historical data time window to maximize accuracy. This study investigates the impact of various…

Machine Learning · Computer Science 2026-05-04 Ramin Mohammadi , Vahab vahdat , Sarthak Jain , Amir T. Namin , Ramya Palacholla , Sagar Kamarthi

Learning from longitudinal electronic health records is limited if it does not capture the temporal trajectories of the patient's state in a clinical setting. Graph models allow us to capture the hidden dependencies of the multivariate…

Machine Learning · Computer Science 2025-03-31 Munib Mesinovic , Soheila Molaei , Peter Watkinson , Tingting Zhu

Health data is a sensitive category of personal data. It might result in a high risk to individual and health information handling rights and opportunities unless there is a palatable defense. Reasonable security standards are needed to…

Cryptography and Security · Computer Science 2020-10-21 Ayan Chatterjee , Ali Shahaab , Martin W. Gerdes , Santiago Martinez , Pankaj Khatiwada

Electronic health records (EHR) consist of longitudinal clinical observations portrayed with sparsity, irregularity, and high-dimensionality, which become major obstacles in drawing reliable downstream clinical outcomes. Although there…

Machine Learning · Computer Science 2020-11-17 Ahmad Wisnu Mulyadi , Eunji Jun , Heung-Il Suk