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We present a novel method for fabricating highly customizable three-dimensional structures hosting quantum sensors based on Nitrogen Vacancy (NV) centers using two-photon polymerization. This approach overcomes challenges associated with…

Vertical optofluidic biosensors based on refractive index sensing promise highest sensitivities at smallest area foot-print. Nevertheless, when it comes to large scale fabrication and application of such sensors, cheap and robust platforms…

Nanodiamonds containing nitrogen-vacancy (NV) centers are promising quantum sensors for biological applications thanks to their sub-micron spatial resolution, biocompatibility, and versatile multi-modal responses. However, the optically…

Applied Physics · Physics 2026-03-23 Shuo Wang , Ming-Zhong Ai , Jing-Wei Fan , Junchen Ye , Chao Lin , Quan Li , Ren-Bao Liu

Laser cooled atoms have proven transformative for precision metrology, playing a pivotal role in state-of-the-art clocks and interferometers, and having the potential to provide a step-change in our modern technological capabilities. To…

Atomic Physics · Physics 2022-10-12 J. P. McGilligan , K. Gallacher , P. F. Griffin , D. J. Paul , A. S. Arnold , E. Riis

Droplet microfluidics offers a versatile platform for analyzing liquid samples. Despite its potential, there is a lack of techniques that allow to reliably probe individual circulating droplets. The prospect of combining droplet…

Quantitative Methods · Quantitative Biology 2024-03-08 Marc Sulliger , Jaime Ortega Arroyo , Romain Quidant

Analysis of nanoscale liquids, including wetting and flow phenomena, is a scientific challenge with far reaching implications for industrial technologies. We report the conception, development, and application of an integrated platform for…

Instrumentation and Detectors · Physics 2017-11-27 M. Engel , P. W. Bryant , R. F. Neumann , R. Giro , C. Feger , P. Avouris , M. Steiner

Atomic vapors, manipulated and probed by light and other electromagnetic fields, constitute versatile and powerful quantum systems for sensing applications. Atoms are identical, isolatable, interfaceable, and intelligible. These features,…

Quantum Physics · Physics 2025-07-18 Justin M. Brown , Thad G. Walker

Quantum sensing using optically addressable atomic-scale defects, such as the nitrogen--vacancy (NV) center in diamond, provides new opportunities for sensitive and highly localized characterization of chemical functionality. Notably,…

The miniaturization and integration of electronic circuitry has not only made the enormous increase in performance of semiconductor devices possible but also spawned a myriad of new products and applications ranging from a cellular phone to…

Fluid Dynamics · Physics 2011-03-16 A. Rathgeber , C. Strobl , H. -J. Kutschera , A. Wixforth

Quantum multiparameter estimation promises to extend quantum advantage to the simultaneous high-precision measurements of multiple physical quantities. However, realizing this capability in practical quantum sensors under realistic…

Single nitrogen vacancy (NV) centers in diamond have been used extensively for high-sensitivity nanoscale sensing, but conventional approaches use confocal microscopy to measure individual centers sequentially, limiting throughput and…

Optical techniques are finding widespread use in analytical chemistry for chemical and bio-chemical analysis. During the past decade, there has been an increasing emphasis on miniaturization of chemical analysis systems and naturally this…

Optics · Physics 2007-11-22 Niels Asger Mortensen , Sanshui Xiao , Jesper Pedersen

Quantum sensors based on nitrogen-vacancy centers in diamond have emerged as a promising detection modality for nuclear magnetic resonance (NMR) spectroscopy owing to their micron-scale detection volume and non-inductive based detection. A…

We demonstrate quantum logic enhanced sensitivity for a macroscopic ensemble of solid-state, hybrid two-qubit sensors. We achieve a factor of 30 improvement in signal-to-noise ratio, translating to a sensitivity enhancement exceeding an…

Quantum technologies have seen a rapid developmental surge over the last couple of years. Though often overshadowed by quantum computation, quantum sensors show tremendous potential for widespread applications in chemistry and biology. One…

Quantum Physics · Physics 2022-05-30 Robin D. Allert , Karl D. Briegel , Dominik B. Bucher

Advances in molecular biology are enabling rapid and efficient analyses for effective intervention in domains such as biology research, infectious disease management, food safety, and biodefense. The emergence of microfluidics and…

Quantitative Methods · Quantitative Biology 2017-03-28 Harikrishnan Jayamohan , Valentin Romanov , Huizhong Li , Jiyoung Son , Raheel Samuel , John Nelson , Bruce Gale

Quantum sensing with nitrogen-vacancy (NV) centers in diamond promises to revolutionize biological research and medical diagnostics. Thanks to their high sensitivity, NV sensors could, in principle, detect specific binding events with…

We report progress toward a CMOS-integrated quantum diamond biosensing platform that combines nitrogen-vacancy (NV) centers in diamond with a custom 40 nm CMOS Single-Photon Avalanche Diode (SPAD) array. The system integrates on-chip active…

Over the years, an enormous effort has been made to establish nitrogen vacancy (NV) centers in diamond as easily accessible and precise magnetic field sensors. However, most of their sensing protocols rely on the application of bias…

Nitrogen-vacancy centers in diamond allow measurement of environment properties such as temperature, magnetic and electric fields at nanoscale level, of utmost relevance for several research fields, ranging from nanotechnologies to…