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We propose machine learning (ML) models to predict the electron density -- the fundamental unknown of a material's ground state -- across the composition space of concentrated alloys. From this, other physical properties can be inferred,…

Machine learning (ML) offers considerable promise for the design of new molecules and materials. In real-world applications, the design problem is often domain-specific, and suffers from insufficient data, particularly labeled data, for ML…

Chemical Physics · Physics 2025-02-04 Ming Han , Ge Sun , Juan J. de Pablo

Generative Flow Networks (GFlowNets), a class of generative models have recently emerged as a suitable framework for generating diverse and high-quality molecular structures by learning from unnormalized reward distributions. Previous works…

Machine Learning · Computer Science 2024-09-17 Mohit Pandey , Gopeshh Subbaraj , Emmanuel Bengio

Predicting molecular properties (e.g., atomization energy) is an essential issue in quantum chemistry, which could speed up much research progress, such as drug designing and substance discovery. Traditional studies based on density…

Computational Physics · Physics 2019-08-20 Chengqiang Lu , Qi Liu , Chao Wang , Zhenya Huang , Peize Lin , Lixin He

Active learning (AL) repeatedly trains the classifier with the minimum labeling budget to improve the current classification model. The training process is usually supervised by an uncertainty evaluation strategy. However, the uncertainty…

Machine Learning · Computer Science 2020-09-29 Xiaofeng Cao

Message passing is the core of most graph models such as Graph Convolutional Network (GCN) and Label Propagation (LP), which usually require a large number of clean labeled data to smooth out the neighborhood over the graph. However, the…

Machine Learning · Computer Science 2021-10-29 Wentao Zhang , Yexin Wang , Zhenbang You , Meng Cao , Ping Huang , Jiulong Shan , Zhi Yang , Bin Cui

Molecule representation learning (MRL) methods aim to embed molecules into a real vector space. However, existing SMILES-based (Simplified Molecular-Input Line-Entry System) or GNN-based (Graph Neural Networks) MRL methods either take…

Machine Learning · Computer Science 2021-09-23 Hongwei Wang , Weijiang Li , Xiaomeng Jin , Kyunghyun Cho , Heng Ji , Jiawei Han , Martin D. Burke

Deep generative models for graph-structured data offer a new angle on the problem of chemical synthesis: by optimizing differentiable models that directly generate molecular graphs, it is possible to side-step expensive search procedures in…

Machine Learning · Statistics 2022-09-28 Nicola De Cao , Thomas Kipf

Active learning (AL) is a promising ML paradigm that has the potential to parse through large unlabeled data and help reduce annotation cost in domains where labeling data can be prohibitive. Recently proposed neural network based AL…

Machine Learning · Computer Science 2022-06-17 Prateek Munjal , Nasir Hayat , Munawar Hayat , Jamshid Sourati , Shadab Khan

There is a lack of scalable quantitative measures of reactivity for functional groups in organic chemistry. Measuring reactivity experimentally is costly and time-consuming and does not scale to the astronomical size of chemical space. In…

Computational Physics · Physics 2021-03-29 Mohammadamin Tavakoli , Aaron Mood , David Van Vranken , Pierre Baldi

Interatomic potentials learned using machine learning methods have been successfully applied to atomistic simulations. However, accurate models require large training datasets, while generating reference calculations is computationally…

Machine Learning · Computer Science 2024-01-23 John Falk , Luigi Bonati , Pietro Novelli , Michele Parrinello , Massimiliano Pontil

Recent machine learning methods make it possible to model potential energy of atomic configurations with chemical-level accuracy (as calculated from ab-initio calculations) and at speeds suitable for molecular dynam- ics simulation. Best…

Computational Physics · Physics 2017-05-03 G. Ferré , T. Haut , K. Barros

Active learning (AL) algorithms may achieve better performance with fewer data because the model guides the data selection process. While many algorithms have been proposed, there is little study on what the optimal AL algorithm looks like,…

Machine Learning · Computer Science 2021-02-23 Yilun Zhou , Adithya Renduchintala , Xian Li , Sida Wang , Yashar Mehdad , Asish Ghoshal

Crystal-graph attention networks have emerged recently as remarkable tools for the prediction of thermodynamic stability and materials properties from unrelaxed crystal structures. Previous networks trained on two million materials…

In this study, we employ Graph Neural Networks (GNNs) to accelerate the discovery of novel 2D magnetic materials which have transformative potential in spintronics applications. Using data from the Materials Project database and the…

Disordered Systems and Neural Networks · Physics 2024-02-06 Ahmed Elrashidy , James Della-Giustina , Jia-An Yan

Gaussian process regression (GPR) or kernel ridge regression is a widely used and powerful tool for nonlinear prediction. Therefore, active learning (AL) for GPR, which actively collects data labels to achieve an accurate prediction with…

Polymers are attractive in applications like flexible electronics and thermal interface materials due to their mechanical compliance and processability. However, conventional polymers have low thermal conductivity (TC), limiting their heat…

Materials Science · Physics 2026-03-25 Yuhan Liu , Jiaxin Xu , Renzheng Zhang , Meng Jiang , Tengfei Luo

Atomistic or ab-initio molecular dynamics simulations are widely used to predict thermodynamics and kinetics and relate them to molecular structure. A common approach to go beyond the time- and length-scales accessible with such…

Building in silico models to predict chemical properties and activities is a crucial step in drug discovery. However, limited labeled data often hinders the application of deep learning in this setting. Meanwhile advances in meta-learning…

Machine Learning · Computer Science 2020-07-21 Cuong Q. Nguyen , Constantine Kreatsoulas , Kim M. Branson

Active learning (AL) aims to minimize labeling efforts for data-demanding deep neural networks (DNNs) by selecting the most representative data points for annotation. However, currently used methods are ill-equipped to deal with biased…

Computer Vision and Pattern Recognition · Computer Science 2020-03-03 Denis Gudovskiy , Alec Hodgkinson , Takuya Yamaguchi , Sotaro Tsukizawa