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The increased availability of electronic health records (EHRs) have spearheaded the initiative for precision medicine using data driven approaches. Essential to this effort is the ability to identify patients with certain medical conditions…

Electronic Health Records are electronic data generated during or as a byproduct of routine patient care. Structured, semi-structured and unstructured EHR offer researchers unprecedented phenotypic breadth and depth and have the potential…

Artificial Intelligence · Computer Science 2017-07-26 Vaclav Papez , Spiros Denaxas , Harry Hemingway

Computational phenotyping has emerged as a practical solution to the incomplete collection of data on gender in electronic health records (EHRs). This approach relies on algorithms to infer a patient's gender using the available data in…

Tensor factorization has been demonstrated as an efficient approach for computational phenotyping, where massive electronic health records (EHRs) are converted to concise and meaningful clinical concepts. While distributing the tensor…

Machine Learning · Computer Science 2019-11-04 Jing Ma , Qiuchen Zhang , Jian Lou , Joyce C. Ho , Li Xiong , Xiaoqian Jiang

Understanding patterns of diagnoses, medications, procedures, and laboratory tests from electronic health records (EHRs) and health insurer claims is important for understanding disease risk and for efficient clinical development, which…

Machine Learning · Computer Science 2022-11-16 Ying Xu , Romane Gauriau , Anna Decker , Jacob Oppenheim

Non-negative tensor factorization has been shown a practical solution to automatically discover phenotypes from the electronic health records (EHR) with minimal human supervision. Such methods generally require an input tensor describing…

Machine Learning · Computer Science 2020-11-13 Kejing Yin , William K. Cheung , Benjamin C. M. Fung , Jonathan Poon

Electronic Health Records (EHR) are data generated during routine clinical care. EHR offer researchers unprecedented phenotypic breadth and depth and have the potential to accelerate the pace of precision medicine at scale. A main EHR…

Quantitative Methods · Quantitative Biology 2017-04-28 Vaclav Papez , Spiros Denaxas , Harry Hemingway

Phenotyping electronic health records (EHR) focuses on defining meaningful patient groups (e.g., heart failure group and diabetes group) and identifying the temporal evolution of patients in those groups. Tensor factorization has been an…

Machine Learning · Computer Science 2019-11-15 Ardavan Afshar , Ioakeim Perros , Haesun Park , Christopher deFilippi , Xiaowei Yan , Walter Stewart , Joyce Ho , Jimeng Sun

Background: The increasing adoption of electronic health records (EHR) across the US has created troves of computable data, to which machine learning methods have been applied to extract useful insights. EHR data, represented as a…

Machine Learning · Computer Science 2021-12-28 Francisco Y Cai , Chengsheng Mao , Yuan Luo

Visual summarization of clinical data collected on patients contained within the electronic health record (EHR) may enable precise and rapid triage at the time of patient presentation to an emergency department (ED). The triage process is…

Human-Computer Interaction · Computer Science 2019-07-26 Nathan C. Hurley , Adrian D. Haimovich , R. Andrew Taylor , Bobak J. Mortazavi

The extraction of phenotype information which is naturally contained in electronic health records (EHRs) has been found to be useful in various clinical informatics applications such as disease diagnosis. However, due to imprecise…

Computation and Language · Computer Science 2019-11-12 Jingqing Zhang , Xiaoyu Zhang , Kai Sun , Xian Yang , Chengliang Dai , Yike Guo

The recent adoption of Electronic Health Records (EHRs) by health care providers has introduced an important source of data that provides detailed and highly specific insights into patient phenotypes over large cohorts. These datasets, in…

This article reviews recent advances in applying natural language processing (NLP) to Electronic Health Records (EHRs) for computational phenotyping. NLP-based computational phenotyping has numerous applications including diagnosis…

Computation and Language · Computer Science 2018-06-18 Zexian Zeng , Yu Deng , Xiaoyu Li , Tristan Naumann , Yuan Luo

This work proposes a new algorithm for automated and simultaneous phenotyping of multiple co-occurring medical conditions, also referred as comorbidities, using clinical notes from the electronic health records (EHRs). A basic latent factor…

Machine Learning · Statistics 2016-09-21 Shalmali Joshi , Suriya Gunasekar , David Sontag , Joydeep Ghosh

It has been recently shown that sparse, nonnegative tensor factorization of multi-modal electronic health record data is a promising approach to high-throughput computational phenotyping. However, such approaches typically do not leverage…

Machine Learning · Computer Science 2018-08-09 Jette Henderson , Bradley A. Malin , Joyce C. Ho , Joydeep Ghosh

Tensor decomposition is an effective tool for learning multi-way structures and heterogeneous features from high-dimensional data, such as the multi-view images and multichannel electroencephalography (EEG) signals, are often represented by…

Machine Learning · Computer Science 2022-06-29 Wanguang Yin , Youzhi Qu , Zhengming Ma , Quanying Liu

Electronic phenotyping is the task of ascertaining whether an individual has a medical condition of interest by analyzing their medical record and is foundational in clinical informatics. Increasingly, electronic phenotyping is performed…

Machine Learning · Statistics 2019-01-08 Daisy Yi Ding , Chloé Simpson , Stephen Pfohl , Dave C. Kale , Kenneth Jung , Nigam H. Shah

With large volumes of health care data comes the research area of computational phenotyping, making use of techniques such as machine learning to describe illnesses and other clinical concepts from the data itself. The "traditional"…

Machine Learning · Statistics 2016-12-30 Chris Hodapp

The paper presents a systematic review of state-of-the-art approaches to identify patient cohorts using electronic health records. It gives a comprehensive overview of the most commonly de-tected phenotypes and its underlying data sets.…

Machine Learning · Statistics 2017-07-25 Norman Hiob , Stefan Lessmann

Electronic Health Records (EHRs) contain extensive patient information that can inform downstream clinical decisions, such as mortality prediction, disease phenotyping, and disease onset prediction. A key challenge in EHR data analysis is…

Applications · Statistics 2026-01-01 Xin Gai , Shiyi Jiang , Anru R. Zhang
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